Abstract: Antimicotically active 2-aminothiazoles have been found having the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl andR.sup.2 represents optionally substituted cyclohexyl or phenyl which is substituted by halogen, alkyl, halogenoalkyl, halogenoalkoxy, dioxyhalogenoalkyl or halogenoalkylthio,and their physiologically tolerable acid addition salts,with the exception of the compounds 4-(4-chlorophenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]thiazole and 4-(2,4-dichlorophenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]-thiazol e and 4-(4-chloro-2-methylphenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]-th iazole and with the exception of the physiologically tolerable acid addition salts of these compoundshave been found.

Abstract: A 2-aminothiazole of the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl andR.sup.2 represents a radical of the formula ##STR2## where R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently of one another in each case represent hydrogen, halogen, nitro, alkyl, alkoxy, alkoxycarbonyl, dialkylamino, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, halogenoalkylsulphinyl or halogenoalkylsulphonyl,X represents oxygen, sulphur, sulphinyl or sulphonyl andAr represents an unsubstituted aryl or a substituted aryl radical,and their physiologically tolerable acid addition salts.

Abstract: A medicinal plaster comprising a covering layer, a reservior layer for an active compound and a detachable protective layer is disclosed. The covering is a substantially impermeable material comprising a textile sheet-like structure which is longitudinally and transversely elastic and is impregnated or coated with a polymer. Disposed on such a covering layer is a reservior layer comprising 1 to 30% by weight of active compound is an elastomeric mixture comprising a polyisobutylene polymer, a carrier such as a polybutadiene oil or liquid paraffin and a resin such as a polybutadiene oil or liquid paraffin and a resin such as a adhesion-conferring resin. Methods for the formation of such medicinal plaster and the use of such medicinal plaster, especially to apply large dosages of antiinflammatory materials are disclosed.

Abstract: The present disclosure is concerned with self-adhesive sheet-like structures made by adhering an adhesive polyurethane gel material to a supporting substrate and the utilization of such structures in the medical field to adhere materials such as plasters, wound dressings and appliances to the human body, and in other fields to connect articles, such as the parts of a fractured or cracked object, to one another by means of an adhesive bond. The gel is formed by immobilizing a high molecular weight polymeric polyol in the matrix of a covalently crosslinked polyurethane which is prepared by reacting polyisocyanates having an isocyanate functionality of at least 2 with higher molecular weight polyhydroxyl compounds having a hydroxyl functionality of at least 3. These reactants are selected in accordance with the following formula which relates the isocyanate number, K, (isocyanate to hydroxyl equivalents ratio times 100) to the average functionalities of the polyisocyanates (F.sub.

Abstract: In a therapeutic system such as a plaster for administration of an active compound through the skin and comprising a covering layer which is essentially impermeable to the active compound, an active compound reservoir layer and a protective layer which can be pulled off and which is essentially impermeable to the active compound, the improvement wherein the reservoir layer contain about 1-30% of active compound in an elastomer mixture comprising a predominantly amorphous olefinic (co)polymer with a glass transition temperature of <20.degree. C., mixed with from 0 up to about 50% by weight of a polyisobutylene, polybutadiene oil and/or paraffin oil, and a tackifying resin. Thereby the active compound can be released in regulated relatively large quantity over a prolonged period of time.

Abstract: In a therapeutic system such as a plaster for administration of an active compound through the skin and comprising a covering layer which is essentially impermeable to the active compound, an active coupound reservoir layer and a protective layer which can be pulled off and which is essentially impermeable to the active compound, the improvement wherein the reservoir layer contains about 1-30% of active compound in an elastomer mixture comprising a diene rubber which can optionally be copolymerized with an .alpha.-olefin, mixed with from 0 up to about 70% by weight of a polyisobutylene, polybutadiene oil and/or paraffin oil, and a tackifying resin. Thereby the active compound can be released in regulated relatively large quantity over a prolonged period of time.

Abstract: In a therapeutic system such as a plaster for administration of an active compound through the skin and comprising a covering layer which is essentially impermeable to the active compound an active compound reservoir layer and a protective layer which can be pulled off and which is essentially impermeable to the active compound, the improvement wherein the reservoir layer contains about 1-30% of active compound in an elastomer mixture comprising at least one of polyisobutylene, polybutadiene oil and paraffin oil, and a tackifying resin. Thereby the active compound can be released in regulated relatively large quantity over a prolonged period of time.

Abstract: The invention relates to a process for production of tampons containing novel formulations of antimycotic azole derivatives which provide a higher release of active compounds and make short-term therapy possible. The tampon formulations of the invention contain active antimycotic azole derivatives in impregnated form, only melting at body temperature, or dissolved form, such as, for example, in suppository bases or their combinations with emulsifiers and/or spreading agents and/or solubilisers.

Abstract: The invention relates to ectoparasiticide-containing polyurethanes which contain spreading agents and ectoparasiticides or mixtures of ectoparasiticides and to said ectoparasiticide-containing polyurethanes in the form of sheets, films, shaped articles, coatings or impregnations. Also included in the invention is the use of said polyurethane compositions for combating ectoparasiticides.

Abstract: The invention relates to ectoparasiticide-containing polyurethane collars for animals containing spreading agents and ectoparasiticides as well as methods for their manufacture.

Abstract: The invention relates to stick formulations of antimycotic azole derivatives containing, in addition to the antimycotic azole derivatives, 3 to 5% by weight relative to the formulation, of benzyl alcohol, 2.5 to 10% by weight, relative to the formulation of spreading agent and one or more auxiliaries.

Abstract: The invention relates to the provision of medicated animal feeds comprising one or more pharmaceutically active compounds and liver meal as a formulation auxiliary. Also included in the invention are methods for the use of said animal feeds of the invention.

Abstract: The instant invention relates to new ectoparasiticidally (especially insecticidally and acaricidally) active animal collars, which are prepared by impregnating suitable carriers with certain ectoparasiticides, and to a process for their preparation.

Abstract: The instant invention relates to plastic compositions having ectoparasiticidal activity, and, in particular, insecticidal and acaricidal, which contain particular ectoparasiticides and polyurethanes, and to animal collars comprising such plastics compositions.