Abstract: Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I? and I?? or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduces the excessive activation of complement.

Abstract: The present teaching relates to obtaining a model for identifying content matching a query. Training data are received which include queries, advertisements, and hyperlinks. A plurality of subwords are identified from each of the queries and a plurality of input vectors for the plurality of subwords of each of the queries are obtained and an input vector for each of the queries is derived based on a plurality of input vectors of a plurality of subwords of the query. A query/ads model is optimized with respect to an objective function via training an input vector for each of the plurality of subwords associated with each of the queries, an input vector for each of the advertisements and links, and a matrix.

Abstract: A syringe having an enteral collar with a vent is disclosed. The syringe may also include a plug which reversibly covers the vent. Other embodiments relate to the use of the syringe. The vent allows fluid within the region between the enteral collar and the tip to be removed.

Abstract: A syringe having an enteral collar with a vent is disclosed. The syringe may also include a plug which reversibly covers the vent. Other embodiments relate to the use of the syringe. The vent allows fluid within the region between the enteral collar and the tip to be removed.

Abstract: The present teaching relates to obtaining a model for identifying content matching a query. Training data are received which include queries, advertisements, and hyperlinks. A plurality of subwords are identified from each of the queries and a plurality of vectors for the plurality of subwords of each of the queries are obtained. Via a neural network, a vector for each of the queries is derived based on a plurality of vectors for the plurality of subwords of the query. A query/ads model is obtained via optimization with respect to an objective function, based on vectors associated with the plurality of subwords of each of the queries and vectors for the queries obtained from the neural network.

Abstract: The present teaching relates to identifying content that matches a query. Train data include queries, advertisement, and hyperlinks associated with query sessions. A plurality of subwords for each of the queries in the training data are identified. A query/ads model is then trained by optimizing vectors associated the plurality of subwords for each of the queries, advertisements, and hyperlinks in the training data with respect to an objective function. At least one vector associated with each of the queries is derived based on the plurality of subword vectors in the query/ads model that represent the plurality of subwords of the query.

Abstract: The present teaching relates to obtaining a model for identifying content matching a query. Training data are received which include queries, advertisements, and hyperlinks. A plurality of subwords are identified from each of the queries and a plurality of input vectors for the plurality of subwords of each of the queries are obtained and an input vector for each of the queries is derived based on a plurality of input vectors of a plurality of subwords of the query. A query/ads model is optimized with respect to an objective function via training an input vector for each of the plurality of subwords associated with each of the queries, an input vector for each of the advertisements and links, and a matrix.