Patents by Inventor Milos Miljkovic

Milos Miljkovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240012022
    Abstract: A method comprises using an atomic-force microscope, acquiring a set of images associated with surfaces, and, using a machine-learning algorithm applied to the images, classifying the surfaces. As a particular example, the classification can be done in a way that relies on surface parameters derived from the images rather than using the images directly.
    Type: Application
    Filed: September 21, 2023
    Publication date: January 11, 2024
    Inventors: Igor Sokolov, Milos Miljkovic
  • Patent number: 11796564
    Abstract: A method comprises using an atomic-force microscope, acquiring a set of images associated with surfaces, and, using a machine-learning algorithm applied to the images, classifying the surfaces. As a particular example, the classification can be done in a way that relies on surface parameters derived from the images rather than using the images directly.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: October 24, 2023
    Assignee: Trustees of Tufts College
    Inventors: Igor Sokolov, Milos Miljkovic
  • Publication number: 20230058610
    Abstract: A method comprises using an atomic-force microscope, acquiring a set of images associated with surfaces, and, using a machine-learning algorithm applied to the images, classifying the surfaces. As a particular example, the classification can be done in a way that relies on surface parameters derived from the images rather than using the images directly.
    Type: Application
    Filed: November 4, 2022
    Publication date: February 23, 2023
    Inventors: Igor Sokolov, Milos Miljkovic
  • Patent number: 11506683
    Abstract: A method comprises using an atomic-force microscope, acquiring a set of images associated with surfaces, and, using a machine-learning algorithm applied to the images, classifying the surfaces. As a particular example, the classification can be done in a way that relies on surface parameters derived from the images rather than using the images directly.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: November 22, 2022
    Assignee: Trustees of Tufts College
    Inventors: Igor Sokolov, Milos Miljkovic
  • Publication number: 20220003798
    Abstract: A method comprises using an atomic-force microscope, acquiring a set of images associated with surfaces, and, using a machine-learning algorithm applied to the images, classifying the surfaces. As a particular example, the classification can be done in a way that relies on surface parameters derived from the images rather than using the images directly.
    Type: Application
    Filed: November 7, 2019
    Publication date: January 6, 2022
    Applicant: Trustees of Tufts College
    Inventors: Igor Sokolov, Milos Miljkovic
  • Patent number: 10067051
    Abstract: A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. In addition, a method for correcting confounding spectral contributions that are frequently observed in microscopically acquired infrared spectra of cells and tissue includes performing a phase correction on the spectral data. This phase correction method may be used to correct various types of absorption spectra that are contaminated by reflective components.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: September 4, 2018
    Assignees: CIRECA THERANOSTICS, LLC, NORTHEASTERN UNIVERSITY
    Inventors: Max Diem, Benjamin Bird, Milos Miljkovic, Stanley H. Remiszewski, Clay M. Thompson
  • Patent number: 9939370
    Abstract: Disclosed herein is a process and system to correct reflective distortions of an optical spectrum. In addition, a spectroscopy system that compensates for reflective distortions is disclosed.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: April 10, 2018
    Assignee: Northeastern University
    Inventors: Max Diem, Benjamin Bird, Milos Miljkovic
  • Patent number: 9436992
    Abstract: Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: September 6, 2016
    Assignee: Northeastern University
    Inventors: Max Diem, Milos Miljkovic, Melissa Romeo, Benjamin Bird, Jennifer Schubert, Kostas Papamarkakis
  • Publication number: 20150213601
    Abstract: Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.
    Type: Application
    Filed: April 3, 2015
    Publication date: July 30, 2015
    Inventors: Max DIEM, Milos MILJKOVIC, Melissa ROMEO, Benjamin BIRD, Jennifer SCHUBERT, Kostas PAPAMARKAKIS
  • Patent number: 9047662
    Abstract: Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: June 2, 2015
    Assignee: Northeastern University
    Inventors: Max Diem, Milos Miljkovic, Melissa Romeo, Benjamin Bird, Jennifer Schubert, Kostas Papamarkakis
  • Publication number: 20150142333
    Abstract: A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. In addition, a method for correcting confounding spectral contributions that are frequently observed in microscopically acquired infrared spectra of cells and tissue includes performing a phase correction on the spectral data. This phase correction method may be used to correct various types of absorption spectra that are contaminated by reflective components.
    Type: Application
    Filed: January 27, 2015
    Publication date: May 21, 2015
    Inventors: Max DIEM, Benjamin BIRD, Milos MILJKOVIC, Stanley H. REMISZEWSKI, Clay M. THOMPSON
  • Patent number: 9025850
    Abstract: A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. In addition, a method for correcting confounding spectral contributions that are frequently observed in microscopically acquired infrared spectra of cells and tissue includes performing a phase correction on the spectral data. This phase correction method may be used to correct various types of absorption spectra that are contaminated by reflective components.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: May 5, 2015
    Assignees: Cireca Theranostics, LLC, Northeastern University
    Inventors: Max Diem, Benjamin Bird, Milos Miljkovic, Stanley H. Remiszewski, Clay M. Thompson
  • Publication number: 20150019155
    Abstract: Disclosed herein is a process and system to correct reflective distortions of an optical spectrum. In addition, a spectroscopy system that compensates for reflective distortions is disclosed.
    Type: Application
    Filed: June 25, 2012
    Publication date: January 15, 2015
    Applicant: NORTHEASTERN UNIVERSITY
    Inventors: Max Diem, Benjamin Bird, Milos Miljkovic
  • Patent number: 8428320
    Abstract: Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: April 23, 2013
    Assignee: Northeastern University
    Inventors: Max Diem, Milos Miljkovic, Melissa Romeo, Benjamin Bird, Jennifer Schubert, Kostas Papamarkakis
  • Publication number: 20120082362
    Abstract: A method for analyzing biological specimens by spectral imaging to provide a medical diagnosis includes obtaining spectral and visual images of biological specimens and registering the images to detect cell abnormalities, pre-cancerous cells, and cancerous cells. This method eliminates the bias and unreliability of diagnoses that is inherent in standard histopathological and other spectral methods. In addition, a method for correcting confounding spectral contributions that are frequently observed in microscopically acquired infrared spectra of cells and tissue includes performing a phase correction on the spectral data. This phase correction method may be used to correct various types of absorption spectra that are contaminated by reflective components.
    Type: Application
    Filed: June 24, 2011
    Publication date: April 5, 2012
    Applicants: Northeastern University, Cellmark Theranostics, LLC
    Inventors: Max Diem, Benjamin Bird, Milos Miljkovic, Stanley H. Remiszewski
  • Publication number: 20110142324
    Abstract: Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.
    Type: Application
    Filed: May 29, 2009
    Publication date: June 16, 2011
    Inventors: Max Diem, Milos Miljkovic, Melissa Romeo, Benjamin Bird, Jennifer Schubert, Kostas Papamarkakis