Patents by Inventor Min Goo Hur
Min Goo Hur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230219054Abstract: The present invention relates to a chitosan-titanium composite, a preparation method and use thereof, and more particularly, a chitosan-titanium composite capable of effectively adsorbing and desorbing 68Ge/68Ga by combining small molecular chitosan with titanium metal oxide to increase adsorption reactivity to 68Ge and 68Ga desorption reactivity, and a preparation method and use thereof.Type: ApplicationFiled: May 26, 2021Publication date: July 13, 2023Inventors: Jun Young Lee, Jeong Hoon Park, Min Goo HUR, Seung Dae YANG
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Patent number: 10675365Abstract: The present invention relates to a curcumin derivative, a method for producing same, and a photo-acoustic imaging agent comprising the curcumin derivative for detecting beta-amyloid plaque. The curcumin derivative, expressed by chemical formula 1, according to the present invention exhibits superb selective bonding with beta-amyloid, thereby allowing beta-amyloid to be detected by means of an optical or photo-acoustic imaging methods, and, particularly, the curcumin derivative can highly effectively detect photo-acoustic signals with almost no noise by reacting to irradiation of light having a particular wavelength range, and thus can be useful as a composition for detecting beta-amyloid and for diagnosing diseases caused by excessive production of beta-amyloid.Type: GrantFiled: September 29, 2016Date of Patent: June 9, 2020Assignee: Korea Atomic Energy Research InstituteInventors: Yong-Dae Park, Jung-Joon Min, Seung-Dae Yang, Min-Goo Hur, Seung-Jin Jung, Yeong-Jin Hong, Seung-Hwan Park
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Publication number: 20190224344Abstract: The present invention relates to a curcumin derivative, a method for producing same, and a photo-acoustic imaging agent comprising the curcumin derivative for detecting beta-amyloid plaque. The curcumin derivative, expressed by chemical formula 1, according to the present invention exhibits superb selective bonding with beta-amyloid, thereby allowing beta-amyloid to be detected by means of an optical or photo-acoustic imaging methods, and, particularly, the curcumin derivative can highly effectively detect photo-acoustic signals with almost no noise by reacting to irradiation of light having a particular wavelength range, and thus can be useful as a composition for detecting beta-amyloid and for diagnosing diseases caused by excessive production of beta-amyloid.Type: ApplicationFiled: September 29, 2016Publication date: July 25, 2019Applicant: Korea Atomic Energy Research InstituteInventors: Yong-Dae Park, Jung-Joon Min, Seung-Dae Yang, Min-Goo Hur, Seung-Jin Jung, Yeong-Jin Hong, Seung-Hwan Park
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Patent number: 8961937Abstract: The present invention relates to a composition for detecting beta amyloid aggregates and a composition for diagnosing beta amyloid aggregation disease, comprising a 2-styrilpyridizine-3(2H)-one derivative or its pharmaceutically acceptable salt, to a diagnostic kit for diagnosing beta amyloid aggregation disease comprising said composition and to a method for detecting beta amyloid aggregates using said compositions to provide information for beta amyloid aggregation disease diagnosis.Type: GrantFiled: March 13, 2013Date of Patent: February 24, 2015Assignee: Korea Atomic Energy Research InstituteInventors: Yong Dae Park, Jeong Hoon Park, Yong Jin Yoon, Seung Tae Yang, Min Goo Hur
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Patent number: 8867686Abstract: Disclosed herein is a high current solid target for radioisotope production at a cyclotron using a metal foam, and more specifically, a high current solid target for isotope production, which attaches a metal foam to the rear surface of the solid target plate. A high current solid target for isotope production including a metal foam according to the present invention may exhibit excellent cooling performances to increase the amount of proton beam current irradiated on the solid target compared to conventional planar-type solid targets. Because the irradiation of the increased proton beam current may increase the amount of an isotope produced per unit time and even an irradiation of proton beam in a short time may allow for production of a desired amount of an isotope, the solid target may be usefully used for production of medical cyclotron nuclides.Type: GrantFiled: June 23, 2010Date of Patent: October 21, 2014Assignee: Korea Atomic Energy Research InstituteInventors: Min Goo Hur, Seung Dae Yang, Sang Wook Kim, In Jong Kim, Sang Mu Choi
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Publication number: 20140134109Abstract: The present invention relates to a composition for detecting beta amyloid aggregates and a composition for diagnosing beta amyloid aggregation disease, comprising a 2-styrilpyridizine-3(2H)-one derivative or its pharmaceutically acceptable salt, to a diagnostic kit for diagnosing beta amyloid aggregation disease comprising said composition and to a method for detecting beta amyloid aggregates using said compositions to provide information for beta amyloid aggregation disease diagnosis.Type: ApplicationFiled: March 13, 2013Publication date: May 15, 2014Inventors: Yong Dae PARK, Jeong Hoon PARK, Yong Jin YOON, Seung Tae YANG, Min Goo HUR
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Patent number: 8111801Abstract: A radioisotope production gas target for producing gas isotopes such as C-11. The radioisotope production gas target includes a target chamber that is in the shape of a hollow cylinder and has a plurality of inner fins protruding from an inner surface thereof along a length thereof, and a body that is shaped of a hollow cylinder enclosing the target chamber, and has a target gas inlet for feeding target gas to a hollow region of the target chamber, a target gas outlet for collecting the target gas after a nuclear reaction occurs, and a first coolant inlet and a first coolant outlet respectively feeding and discharging a coolant flowing along an outer surface of the target chamber, and includes a thin metal sheet in front thereof through which a beam of protons passes.Type: GrantFiled: October 21, 2008Date of Patent: February 7, 2012Assignee: Korea Atomic Energy Research InstituteInventors: Min Goo Hur, Sang Wook Kim, Seung Dae Yang
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Patent number: 8073095Abstract: An F-18 production target system having an internal support produces F-18 by means of a nuclear reaction of protons and H218O, and reduces the deformation of thin sheets to thus increase the durability of the thin sheets. The F-18 production target system includes a frame, which has the shape of a cylinder the central portion of which is bored, holds H218O in the central portion, and includes through-holes bored from the central portion to the outer circumference thereof, thin sheets, which are installed on opposite sides of the frame so as to seal the central portion, and a support, which is installed in the central portion so as to prevent the thin sheets from being deformed.Type: GrantFiled: July 11, 2008Date of Patent: December 6, 2011Assignee: Korea Atomic Energy Research InstituteInventors: Min Goo Hur, Seung Dae Yang, Sang Wook Kim
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Publication number: 20110091001Abstract: Disclosed herein is a high current solid target for radioisotope production at a cyclotron using a metal foam, and more specifically, a high current solid target for isotope production, which attaches a metal foam to the rear surface of the solid target plate. A high current solid target for isotope production including a metal foam according to the present invention may exhibit excellent cooling performances to increase the amount of proton beam current irradiated on the solid target compared to conventional planar-type solid targets. Because the irradiation of the increased proton beam current may increase the amount of an isotope produced per unit time and even an irradiation of proton beam in a short time may allow for production of a desired amount of an isotope, the solid target may be usefully used for production of medical cyclotron nuclides.Type: ApplicationFiled: June 23, 2010Publication date: April 21, 2011Applicant: Korea Atomic Energy Research InstituteInventors: Min Goo Hur, Seung Dae Yang, Sang Wook Kim, In Jong Kim, Sang Mu Choi
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Publication number: 20090274259Abstract: A radioisotope production gas target for producing gas isotopes such as C-11. The radioisotope production gas target includes a target chamber that is in the shape of a hollow cylinder and has a plurality of inner fins protruding from an inner surface thereof along a length thereof, and a body that is shaped of a hollow cylinder enclosing the target chamber, and has a target gas inlet for feeding target gas to a hollow region of the target chamber, a target gas outlet for collecting the target gas after a nuclear reaction occurs, and a first coolant inlet and a first coolant outlet respectively feeding and discharging a coolant flowing along an outer surface of the target chamber, and includes a thin metal sheet in front thereof through which a beam of protons passes.Type: ApplicationFiled: October 21, 2008Publication date: November 5, 2009Applicant: Korea Atomic Energy Research InstituteInventors: Min Goo Hur, Sang Wook Kim, Seung Dae Yang
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Publication number: 20090260971Abstract: Disclosed herein is a method of preparing a fluoroalkyl compound using radiation, including: mixing an alkyl compound having a leaving group with tetrabutylammonium fluoride (TBAF) in the presence of a reaction solvent at room temperature to form a mixed solution (step 1); and applying radiation to the mixed solution while stirring it to prepare a fluoroalkyl compound (step 2). The method of preparing a fluoroalkyl compound using radiation is advantageous in that fluoroalkyl compounds can be easily prepared in a short reaction time at room temperature, in that the method is safe because it is not required to use fluorine gas, which is harmful to the human body, in that the method can be usefully used to prepare fluoroalkyl compounds because the yield of fluoroalkyl compounds obtained using the method is higher than when using conventional SN2 reaction methods, and in that fluorine 18F, which is a radioactive isotope, can be easily introduced into alkyl compounds.Type: ApplicationFiled: October 2, 2008Publication date: October 22, 2009Applicant: Korea Atomic Energy Research InstituteInventors: Sang Wook Kim, Min Goo Hur, Seung Dae Yang, Kook Hyun Yu
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Publication number: 20090016478Abstract: An F-18 production target system having an internal support produces F-18 by means of a nuclear reaction of protons and H218O, and reduces the deformation of thin sheets to thus increase the durability of the thin sheets. The F-18 production target system includes a frame, which has the shape of a cylinder the central portion of which is bored, holds H218O in the central portion, and includes through-holes bored from the central portion to the outer circumference thereof, thin sheets, which are installed on opposite sides of the frame so as to seal the central portion, and a support, which is installed in the central portion so as to prevent the thin sheets from being deformed.Type: ApplicationFiled: July 11, 2008Publication date: January 15, 2009Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Min Goo Hur, Seung Dae Yang, Sang Wook Kim