Abstract: Disclosed are methods for testing the presence and/or activity of glutathione system components and thioredoxin system components during the manufacturing process of disulfide bond-containing proteins. Also disclosed are methods for mitigating reduction of disulfide bonds during the manufacturing process, and for lowering the reduction potential of disulfide bond-containing proteins. Provided are compositions, kits, and methods for mitigating reduction and diminishing reduction potential of disulfide bond-containing proteins during protein manufacturing processes.

Abstract: A task allocating method for a reconfigurable processing system is provided by the present disclosure. The method includes determining a use status of a hardware processing resource of the reconfigurable processing system. The hardware processing resource includes m task channels and a reconfigurable computing array, and one task channel controls at least one operator in the reconfigurable computing array at a time to process one task. The number m is a positive integer and allocating a first task in n tasks to be processed according to the use status of the hardware processing resource, so that at least one task channel in the m task channels controls the reconfigurable computing array to process simultaneously at least one task which includes the first task, where the number n is a positive integer. A task allocating system for a reconfigurable processing system is also provided by the present disclosure.

Abstract: A computer-executable method, computer program product, and system for parsing a data log from a device, the computer-executable method comprising receiving the data log from the device, sampling the data log to create a sampled portion of data, wherein the sampled portion of data includes each attribute in the data log, constructing a metadata table based on the sampled portion of data, constructing data dictionaries based on the sampled portion of data, and parsing the data log using the metadata table and the data dictionaries to create a data field mapping table.

Abstract: Provided are a CaMg2-based alloy hydride material for hydrolysis production of hydrogen, a preparation method therefor and a use thereof. The material has a general formula of CaMgxMyHz, wherein M is Ni, Co or Fe, 1.5?x<2.0, 0<y?0.5, and 3?z<6. The preparation method for the material comprises the following steps: (1) stacking three pure metal block materials in a crucible, wherein a metal block material M is placed at the top; (2) installing the crucible in a high-frequency induction melting furnace, evacuating and introducing an argon gas; (3) starting the high-frequency induction melting furnace to heat at a low power first, then increasing the power to uniformly fuse same; and thereafter cooling with the furnace to obtain an alloy ingot, and hammer-milling to obtain a hydrogen storage alloy based on CaMg2; and (4) hydrogenating the hammer-milled hydrogen storage alloy to obtain the material for hydrolysis production of hydrogen. The preparation method is simple and low in cost.

Abstract: Provided is a cardiac virtualization test tank and testing system and method. A test tank is provided that includes a physical heart model representing the structure of the heart and a plurality of electrodes that output simulated biopotential signals based on an EP model representing the electrophysiological activity of the heart. The test system can be used for training, teaching, or validating a cardiac mapping, diagnosis, and/or treatment system, as examples.

Abstract: According to one aspect, a portable electronic device having a base portion having a keypad, and a sliding portion. The sliding portion is coupled to the base portion and slideable relative thereto between a closed position wherein the keypad is covered by the sliding portion, and an open position wherein the keypad is exposed. The keypad includes a plurality of keys, at least some of the plurality of keys having a ridge that extends upwardly from the top surface of the key. Each ridge extends between a lower edge of the key and an upper edge of the key and is curved therebetween. Each ridge is offset from a midline of each key.

Abstract: The invention discloses a novel four-direction headrest, which comprises a headrest housing, a U-shaped headrest bar, a Z-direction sliding fixing socket, an unlocking mechanism bracket, a tab, a tab return spring, an X-direction sliding fixing socket, an X-direction sliding guide, an unlocking steel wire, an unlocking button, wherein the locking and unlocking among the X-direction sliding fixing socket, the unlocking mechanism bracket, and the U-shaped headrest bar is realized by the unlocking steel wire, and the locking and unlocking between the tab and the X-direction sliding guide is realized by the tab movement driven by the unlocking steel wire. The locking and unlocking mechanism of the invention is simple, efficient and controllable.

Abstract: Docetaxel and doxorubicin can be formulated in liposomal pharmaceutical compositions. In various embodiments, the pharmaceutical compositions include (i) a first liposome type comprising a first lipid layer comprising an unsaturated phospholipid, cholesterol or a cholesterol derivative, DC-cholesterol, a cationic lipid, and preferably a pegylated phospholipid, and a first active pharmaceutical ingredient (API) comprising docetaxel in the first lipid layer; and (ii) a second liposome type comprising a second lipid layer, an aqueous interior, and a second API comprising doxorubicin crystallized in the aqueous interior, (iii) where the first liposome type does not comprise doxorubicin and the second liposome type does not comprise docetaxel. The pharmaceutical composition can be used to treat a subject, for example, a human subject having cancer.

Abstract: Disclosed is a method for data analyzing and processing, comprising: entering a pre-established new data analysis and processing project; accessing a functional node in the new data analysis and processing project; reading a target file and importing data; generating a data calculation and processing script according to a requirement information; and calling the data calculation and processing script, and analyzing and processing the data at the functional node.

Abstract: This disclosure provides an emergency handling method, comprising: receiving, by an emergency support function (ESF) entity, an emergency indicator indicating an emergency event from a network application server; handling the emergency indictor to derive related parameters including impacted network elements in a network; and triggering the impacted network elements to switch into a network emergency mode by sending an emergency command based on the related parameters. An emergency handling apparatus in a network is also provided. This improves efficiency of emergency handling in a network.

Abstract: Exemplary embodiments allocate network traffic among multiple paths in a network, which may include one or more preferred paths (e.g. shortest paths) and one or more alternative paths (e.g., non-shortest paths). In one embodiment, network traffic in form of flows may be allocated to the preferred paths until the allocation of additional network traffic would exceed a predetermined data rate. Additional flows may then be sent over the alternative paths, which may be longer than the preferred path. The paths to which each flow is assigned may be dynamically updated, and in some embodiments the path assignment for a particular flow may time out after a predetermined time. Accordingly, the flow traffic of each path may be balanced based on real-time traffic information.

Abstract: Docetaxel and doxorubicin can be formulated in liposomal pharmaceutical compositions. In various embodiments, the pharmaceutical compositions include (i) a first liposome type comprising a first lipid layer comprising an unsaturated phospholipid, cholesterol or a cholesterol derivative, DC-cholesterol, a cationic lipid, and preferably a pegylated phospholipid, and a first active pharmaceutical ingredient (API) comprising docetaxel in the first lipid layer; and (ii) a second liposome type comprising a second lipid layer, an aqueous interior, and a second API comprising doxorubicin crystallized in the aqueous interior, (iii) where the first liposome type does not comprise doxorubicin and the second liposome type does not comprise docetaxel. The pharmaceutical composition can be used to treat a subject, for example, a human subject having cancer.

Abstract: Disclosed is a nonwoven fabric formed from (i) a nonwoven fabric substrate and (ii) a fluorine-containing polymer adhering to the nonwoven fabric substrate, wherein the fluorine-containing polymer contains: (a) repeating units formed from a fluorine-containing monomer which is alpha-chloro acrylate or alpha-chloro acrylamide containing a fluoroalkyl group, and (b) repeating units formed from a halogenated olefin monomer, and the fluorine-containing polymer is free from repeating units formed from a (meth)acrylate containing a linear or branched hydrocarbon group having at least 18 carbon atoms.

Abstract: The present invention provides for a process for preparing liposomes, lipid discs, and other lipid nanoparticles using a multi-port manifold, wherein the lipid solution stream, containing an organic solvent, is mixed with two or more streams of aqueous solution (e.g., buffer). In some aspects, at least some of the streams of the lipid and aqueous solutions are not directly opposite of each other. Thus, the process does not require dilution of the organic solvent as an additional step. In some embodiments, one of the solutions may also contain an active pharmaceutical ingredient (API). This invention provides a robust process of liposome manufacturing with different lipid formulations and different payloads. Particle size, morphology, and the manufacturing scale can be controlled by altering the port size and number of the manifold ports, and by selecting the flow rate or flow velocity of the lipid and aqueous solutions.

Abstract: Provided are a CaMg2-based alloy hydride material for hydrolysis production of hydrogen, a preparation method therefor and a use thereof. The material has a general formula of CaMgxMyHz, wherein M is Ni, Co or Fe, 1.5?x<2.0, 0<y?0.5, and 3?z<6. The preparation method for the material comprises the following steps: (1) stacking three pure metal block materials in a crucible, wherein a metal block material M is placed at the top; (2) installing the crucible in a high-frequency induction melting furnace, evacuating and introducing an argon gas; (3) starting the high-frequency induction melting furnace to heat at a low power first, then increasing the power to uniformly fuse same; and thereafter cooling with the furnace to obtain an alloy ingot, and hammer-milling to obtain a hydrogen storage alloy based on CaMg2; and (4) hydrogenating the hammer-milled hydrogen storage alloy to obtain the material for hydrolysis production of hydrogen. The preparation method is simple and low in cost.

Abstract: The present invention provides an application method for cold field plasma discharge assisted high energy ball milled powder and a plasma assisted high energy ball milling device using the method for cold field plasma high energy ball milled powder. The present invention generates plasma by using dielectric barrier discharge and introducing a dielectric barrier discharge electrode bar into a high-speed vibrating ball milling tank, which requires that, on one hand, a solid insulation medium on the outer layer of the electrode bar can simultaneously bear high-voltage discharge and mechanical shock failure of the grinding ball, and on the other hand, the high-speed vibrating ball milling device can uniformly process the powder.

Abstract: Adipose derived regenerative cells are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells, e.g., stem and/or progenitor cells, obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, adipose derived regenerative cells are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.

Abstract: A method for preparing a magnesium-based hydrogen storage material, includes: a Mg—Ce—Ni family amorphous alloy is prepared by a rapid cooling process; the amorphous alloy is pulverized, so as to obtain a amorphous powder; the amorphous alloy is activated, so as to obtain a MgH2—Mg2NiH4—CeH2.73 family nanocrystalline composite; the abovementioned composite is carried out a hydrogen absorption and desorption cycle, then the composite is placed in a pure Ar atmosphere for passivation, finally, the passivated composite is oxidized, so as to obtain a MgH2—Mg2NiH4—CeH2.73—CeO2 family nanocrystalline composite.

Abstract: In one embodiment, a method includes receiving at a location related failure identification device, failure data for a plurality of components within a system, mapping at the device, the failure data to location data comprising a location of each of the components within the system, identifying at the device, location related failures based on the mapping, and outputting from the device, information on the location related failures. An apparatus and logic are also disclosed herein.

Abstract: A magnetic currency verification head may include a magnetoresistive sensor chip, and a magnetic bias unit disposed on the side of the magnetoresistive sensor chip away from the detection surface of the magnetic currency verification head, and separated from the magnetoresistive sensor chip; the magnetoresistive sensor chip comprises a gradiometric bridge circuit that includes magnetic sensor elements; the sensitive direction of the magnetic sensor elements is parallel to the detection surface of the magnetic currency verification head; and the magnetic bias unit has a recessed magnetic structure configured such that the magnetic field generated by the magnetic bias unit only has a small magnetic field component in the direction parallel to the detection surface, thereby enabling the magnetic sensor elements to operate in their linear range. As a result, the magnetic currency verification head has high sensitivity and signal-to-noise ratio.