Abstract: An information processing device including a calculation unit that calculates an evaluation function using a visibility threshold of a test subject obtained by performing a visual acuity examination on the test subject and using a parameter related to a visual object, and a spectral transmittance optimization unit that optimizes a spectral transmittance of a filter having a spectral transmittance to light from the visual object using the evaluation function when passed through the filter.

Abstract: A reactor comprises a main body having a flow path substrate and a crystal substrate chemically bonded to the flow path substrate to form a flow path for running a sample to be measured and a reactor tank connected to the flow path. An adsorption film is disposed in the reactor tank for adsorbing a specific substance contained in the sample to be measured. A measuring device measures a physical quantity of the specific substance contained in the sample and adsorbed by the adsorption film.

Abstract: A blood rheology measuring apparatus has a measuring portion for measuring a flow velocity of the blood flowing in a blood vessel of a person in a mode of a Doppler shift signal by transmitting and receiving a wave to and from a surface of the person's skin. An information processing portion calculates an intensity at each of frequency components of the Doppler shift signal, extracts a maximum frequency in a signal at an intensity level equal to or larger than a threshold in the histogram or a maximum frequency when an integrated value from a low frequency component reaches a predetermined rate of a total thereof in the histogram, and provides a temporal change waveform of the extracted frequency. The blood rheology is analyzed by an area value of a portion at and above a line connecting a minimum value of one pulse waveform and a minimum value of a successive pulse waveform of the frequency waveform.

Abstract: A blood rheology measuring apparatus has a measuring portion for measuring a flow velocity of the blood flowing in a blood vessel of a person in a mode of a Doppler shift signal by transmitting and receiving a wave to and from a surface of the person's skin. An information processing portion calculates an intensity at each of frequency components of the Doppler shift signal, extracts a maximum frequency in a signal at an intensity level equal to or larger than a threshold in the histogram or a maximum frequency when an integrated value from a low frequency component reaches a predetermined rate of a total thereof in the histogram, and provides a temporal change waveform of the extracted frequency. The blood rheology is analyzed based on the maximum frequency in the frequency waveform.

Abstract: A microchip has a substrate on which there are formed a reaction bath section, a first flow channel to which are connected a supply channel that supplies a buffer solution and the reaction bath section, a second flow channel to which are connected a supply channel that supplies a sample solution containing a first substance and a channel that discharges the sample and buffer solutions to an exterior of the substrate, and a connecting channel connecting the first flow channel to the second flow channel. The reaction bath section receives the first and second substances so that the first and second substances react in the reaction bath section.

Abstract: In a method of calculating circulation dynamics of a living body, a resistance component corresponding to a shape of a blood vessel in the living body is derived using previously obtained values of viscosity, pressure and flow rate of blood flowing in the blood vessel. Information corresponding to the viscosity of the blood is calculated using the derived resistance component.

Abstract: To provide a noninvasive type blood rheology measuring apparatus capable of simply and conveniently measuring blood rheology information without sampling blood from a subject in measuring the blood rheology and a small-sized and portable apparatus, a blood rheology measuring apparatus of the invention is on a basis of a constitution including means form on invasively detecting a flow velocity of the blood flowing in the blood vessel as a Doppler shift signal by transmitting and receiving a wave from the face of the skin and means for analyzing blood rheology by a temporal change of the flow velocity value of the blood detected by the means.

Abstract: A blood rheology measuring apparatus has a measuring portion for measuring a flow velocity of the blood flowing in a blood vessel of a person in a mode of a Doppler shift signal by transmitting and receiving a wave to and from a surface of the person's skin. An information processing portion calculates an intensity at each of frequency components of the Doppler shift signal, extracts a maximum frequency in a signal at an intensity level equal to or larger than a threshold in the histogram or a maximum frequency when an integrated value from a low frequency component reaches a predetermined rate of a total thereof in the histogram, and provides a temporal change waveform of the extracted frequency. The blood rheology is analyzed based on the maximum frequency in the frequency waveform.

Abstract: A blood rheology measuring apparatus has a measuring portion for measuring blood circulation information inside of a living body from outside of the living body. The blood circulation information is a maximum blood flow velocity for one pulse. An information processing portion processes the measured information from the measuring portion to obtain information concerning a blood rheology of the living body.

Abstract: In order to provide a reactor, a micro reactor chip, and a micro reactor system which can maintain high sensitivity without residual stresses on a crystal oscillator and unwanted oscillation modes, both surfaces of an AT-cut crystal plate 100 is deposited or sputtered with gold to prepare a detection electrode 601, an opposite electrode 602, and wiring to both electrodes. A resist is then formed on a cleaned silicon wafer. Polydimethylsiloxane (PDMS) is then poured onto the silicon wafer and allowed to cure. The PDMS is then peeled from the silicon wafer to form a groove 500 in the PDMS. The PDMS is then laid on the crystal plate. When the crystal substrate side is then irradiate with ultraviolet light the silicon-carbon bond between the crystal and the PDMS is cut, thus causing the crystal and the PDMS to bond to each other by means of a siloxane bond. The liquid introduction port and the liquid discharge port are then cut to form the reactor.

Abstract: In order to make it possible to predict a dissociation constant at an initial stage of reaction, a concentration sensor for a sample is provided on a downstream side of a mass sensor. This makes it possible to learn concentration of a sample solution at the time when a mass is detected by the mass sensor. When the concentration and the mass are substituted in a predetermined logical expression, it is possible to obtain a predicted value of a dissociation constant. The concentration sensor is a capacitor constituted by electrodes opposed to each other. Since a dielectric constant changes when analytes are present between the electrodes, it is possible to detect analyte concentration according to the dielectric constant. Since it is possible to reduce a size of the capacitor, it is possible to keep a size of a micro-reactor small. Note that the mass sensor outputs a resonance frequency of a quartz resonator. A measuring apparatus can calculate a mass from transition of this frequency.

Abstract: It is a problem to provide a microchip for analysis which is miniaturized, is disposable for ease to use, and does not have a risk of contamination in flow channels. On a substrate 2, a first flow channel having a buffer solution supply channel 6 and a reaction bath section 3, a second flow channel having a sample solution supply channel 5 and a waste solution channel 7, and a connecting channel 9 connecting both the flow channels upstream of the reaction bath section 3 are provided. The waste solution channel 7 and the reaction bath section 3 are connected to a waste solution tank 8 and a pump 11. After a ligand is modified in the reaction bath section 3, a sample solution is allowed to flow in the sample solution supply channel 5 and the waste solution channel 7, and a buffer solution is allowed to flow in the buffer solution supply channel 6, the connecting channel 9 and the waste solution channel 7, subsequently to flow in the buffer solution supply channel 6 and the reaction bath section 3.

Abstract: When a wave is noninvasively inputted through a surface of a living body to be reflected by a body fluid flowing through the living body, and the state of blood and the like is analyzed on the basis of the motion and the position to obtain circulation information in order to evaluate the health state, the circulation information can be accurately measured irrespective of the degree of strain of a blood vessel of a part to be measured in the living body. In a circulation dynamics measuring apparatus having a circulation sensor portion for transmitting/receiving a wave to/from the inside of the living body through a surface of the living body, and a processing portion for calculating a circulation dynamics from the received wave, the circulation sensor portion has a portion for measuring a blood pressure and a portion for measuring a blood flow rate, and information concerned with viscosity of blood is calculated by the processing portion.

Abstract: To provide a noninvasive type blood rheology measuring apparatus capable of simply and conveniently measuring blood rheology information without sampling blood from a subject in measuring the blood rheology and a small-sized and portable apparatus, a blood rheology measuring apparatus of the invention is on a basis of a constitution including means for noninvasively detecting a flow velocity of the blood flowing in the blood vessel as a Doppler shift signal by transmitting and receiving a wave from the face of the skin and means for analyzing blood rheology by a temporal change of the flow velocity value of the blood detected by the means.

Abstract: A cooling unit is structured such that a temperature sensor is formed on at least one of the substrates that form a thermoelectric conversion device to which thermoelectric elements are connected, an input/output electrode extending from the temperature sensor and an electrode formed on the other surface opposed to the substrate on which the temperature sensor is formed are connected to each other by electrically conductive material, and a control circuit for controlling a current supplied to the thermoelectric conversion device according to an output of the temperature sensor is connected thereto. By this structure, only one surface of the substrate is subjected to a manufacturing process, and there is no need for a temperature sensor such as a thermistor to be supplied as a discrete component for mounting on a substrate of the thermoelectric conversion device.

Abstract: A .pi.-type thermoelectric conversion component detects and controls temperature and at the same time exhibits a cooling performance inherently possessed by the thermoelectric conversion component without the need for mounting a discrete temperature detecting unit. To achieve this, a temperature detecting unit, such as a thin film thermistor or doped semiconductor region, is directly integrated on a surface of a substrate forming the thermoelectric component. In one embodiment, a monocrystalline silicon wafer is used as at least one of the opposing substrates of the thermoelectric conversion component, a temperature detecting unit having a diffused resistor is formed therein. An electrode of the temperature detecting unit is connected to an electrode formed on the opposing substrate to reduce the thermal load.