Patents by Inventor Mindy M. Steiniger-White

Mindy M. Steiniger-White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tn5 transposase mutants and the use thereof
    Patent number: 7083980
    Abstract: Tn5 transposase (Tnp) mutants that have higher transposase activities than the wild-type Tnp are disclosed. The Tn5 Tnp mutants differ from the wild-type Tnp at amino acid positions 54, 242, and 372 and have greater avidity than the wild-type Tnp for at least one of a wild-type Tn5 outside end sequence as defined by SEQ ID NO:3 and a modified Tn5 outside end sequence as defined by SEQ ID NO:5. Also disclosed are various systems and methods of using the Tnp mutants for in vitro or in vivo transposition.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: August 1, 2006
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: William S. Reznikoff, Mindy M. Steiniger-White, Jeremy D. Metzler
  • Tn5 transposase mutants and the use thereof
    Publication number: 20040235103
    Abstract: Tn5 transposase (Tnp) mutants that have higher transposase activities than the wild-type Tnp are disclosed. The Tn5 Tnp mutants differ from the wild-type Tnp at amino acid positions 54, 242, and 372 and have greater avidity than the wild-type Tnp for at least one of a wild-type Tn5 outside end sequence as defined by SEQ ID NO:3 and a modified Tn5 outside end sequence as defined by SEQ ID NO:5. Also disclosed are various systems and methods of using the Tnp mutants for in vitro or in vivo transposition.
    Type: Application
    Filed: April 16, 2004
    Publication date: November 25, 2004
    Inventors: William S. Reznikoff, Mindy M. Steiniger-White, Jeremy D. Metzler