Patents by Inventor Mindy Simon

Mindy Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Real-time, label-free detection of nucleic acid amplification in droplets using impedance spectroscopy and solid-phase substrate
    Patent number: 9030215
    Abstract: A method for detecting presence of nucleic acid amplification in a test droplet. A set of detection electrodes are provided in contact with a fluidic channel. The test droplet is provided in vicinity of the detection electrodes through the fluidic channel. An alternate current (AC) power at a first frequency is applied across the set of detection electrodes. A first measurement value that reflects electrical impedance of the test droplet at the first frequency is obtained. This value is compared with a corresponding reference value, wherein the corresponding reference value is obtained by measuring a reference droplet containing known amplified nucleic acid or known unamplified nucleic acid at the first frequency. The presence of amplified nucleic acid in the test droplet is thus determined based on the comparison.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: May 12, 2015
    Assignee: The Regents of the University of California Corporation
    Inventors: Abraham P. Lee, Javier Lopez-Prieto, Robert Lin, Mindy Simon, Nick Martin
  • Real-time, label-free detection of nucleic acid amplification in droplets using impedance spectroscopy and solid-phase substrate
    Publication number: 20130154671
    Abstract: A method for detecting presence of nucleic acid amplification in a test droplet. A set of detection electrodes are provided in contact with a fluidic channel. The test droplet is provided in vicinity of the detection electrodes through the fluidic channel. An alternate current (AC) power at a first frequency is applied across the set of detection electrodes. A first measurement value that reflects electrical impedance of the test droplet at the first frequency is obtained. This value is compared with a corresponding reference value, wherein the corresponding reference value is obtained by measuring a reference droplet containing known amplified nucleic acid or known unamplified nucleic acid at the first frequency. The presence of amplified nucleic acid in the test droplet is thus determined based on the comparison.
    Type: Application
    Filed: October 3, 2012
    Publication date: June 20, 2013
    Inventors: Abraham P. Lee, Javier Lopez-Prieto, Robert Lin, Mindy Simon, Nick Martin