Patents by Inventor Minenobu Okayama

Minenobu Okayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9683006
    Abstract: The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: June 20, 2017
    Assignee: Sumitomo Bakelite Co., Ltd.
    Inventors: Shinichiro Nishimura, Kenichi Niikura, Hiroaki Nakagawa, Minenobu Okayama
  • Patent number: 9139607
    Abstract: The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated.
    Type: Grant
    Filed: December 25, 2003
    Date of Patent: September 22, 2015
    Assignee: Sumitomo Bakelite Co., Ltd.
    Inventors: Shinichiro Nishimura, Kenichi Niikura, Hiroaki Nakagawa, Minenobu Okayama
  • Publication number: 20150175652
    Abstract: The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated.
    Type: Application
    Filed: December 23, 2014
    Publication date: June 25, 2015
    Inventors: Shinichiro Nishimura, Kenichi Niikura, Hiroaki Nakagawa, Minenobu Okayama
  • Publication number: 20090155316
    Abstract: An oral wash comprising an aqueous dispersion of transition metal fineparticles such as platinum colloid. The wash is capable of conveniently and quickly eliminating active oxygen species which causes damages of mucosa in the oral cavity, periodontium, and the like.
    Type: Application
    Filed: December 13, 2005
    Publication date: June 18, 2009
    Applicants: APT CO., LTD., DENTALARROW CO., LTD.
    Inventors: Minenobu Okayama, Kenichi Koshiro
  • Publication number: 20060188996
    Abstract: The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated.
    Type: Application
    Filed: December 25, 2003
    Publication date: August 24, 2006
    Applicant: Shionogi Co., Ltd.
    Inventors: Shinichiro Nishimura, Kenichi Niikura, Hiroaki Nakagawa, Minenobu Okayama
  • Patent number: 5912300
    Abstract: The present invention provides a poly-amino acidic oligonucleotide-carrier comprising a poly-lysine:serine random copolymer.This carrier is bonded with oligonucleotide without causing precipitation, and smoothly releases the bonded oligonucleotide within cells. It is therefore useful as an in vivo transport carrier of an oligonucleotide drug against various genetic diseases and viral diseases such as AIDS. It also makes a great contribution to creation of various useful animals and plants by genetic engineering technique, including virus-resistant plants.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: June 15, 1999
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Minenobu Okayama, Yosuke Suzuki, Akira Wada
  • Patent number: 5800809
    Abstract: The present invention provides a non-crosslinked acrylic polymer and a non-crosslinked anionic exchange resin consisting of polyacryloyloxyethyl-N,N-dimethylbenzyl ammonium salt.
    Type: Grant
    Filed: March 13, 1997
    Date of Patent: September 1, 1998
    Assignee: Hisamitsu Pharmaceutical Co, Inc
    Inventors: Minenobu Okayama, Shuji Sato
  • Patent number: 5665348
    Abstract: A cholesterol-lowering drug which comprises, as the main ingredient, a non-crosslinked anion exchange resin consisting of structural units represented by the general formula (I): ##STR1## wherein R.sub.1 represents a benzyl group or an alkyl group having 1 to 20 carbon atoms, R.sub.2 and R.sub.3 may be identical with, or different from, each other and each represent a lower alkyl group having 1 to 4 carbon atoms, R.sub.4 represents a hydrogen atom or a lower alkyl group, X represents a physiologically acceptable counter ion, n is an integer of from 1 to 3, and p is an average degree of polymerization ranging from 10 to 10,000.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: September 9, 1997
    Assignee: Hisamitsu Pharmaceutical Co, Inc.
    Inventors: Minenobu Okayama, Shuji Sato
  • Patent number: 5654004
    Abstract: An oral pharmaceutical preparation releasable in the lower digestive tract, characterized by having a double-coated structure wherein a solid drug having a core containing an active ingredient is covered with both an inner coat made of a cationic polymer and an outer coat made of an anionic polymer.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: August 5, 1997
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Minenobu Okayama, Masaru Nakanishi