Patents by Inventor Ming-Jer Tsai
Ming-Jer Tsai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8768619Abstract: A road side data exchange net and method thereof is provided. The road side data exchange net includes a plurality of road side data exchange devices set on neighboring roads separately. The road side data exchange device includes a positioning system for receiving satellite data regularly, a calculator for calculating a calibration value of the satellite data to generate an analyzed result data, and a database for storing the analyzed result data. Further, each of the road side data exchange devices broadcasts the analyzed result data from its database to all of neighboring road side data exchange devices to provide the analyzed result data to an electronic device.Type: GrantFiled: June 7, 2012Date of Patent: July 1, 2014Assignee: National Tsing Hua UniversityInventors: Yu-Tsen Hsieh, Chih-Wei Hsu, Yuan-Po Cheng, Ming-Jer Tsai
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Publication number: 20130261963Abstract: A road side data exchange net and method thereof is provided in an embodiment of the present invention. The road side data exchange net includes a plurality of road side data exchange devices. The road side data exchange devices are set on neighboring roads separately. The road side data exchange device includes a positioning system for receiving satellite data regularly; a calculator for calculating a calibration value of the satellite data to generate an analyzed result data; a database for storing the analyzed result data. Further each of the road side data exchange devices broadcasts the analyzed result data from its database to all of neighboring road side data exchange devices to provide the analyzed result data to an electronic device.Type: ApplicationFiled: June 7, 2012Publication date: October 3, 2013Inventors: Yu-Tsen HSIEH, Chih-Wei HSU, Yuan-Po CHENG, Ming-Jer TSAI
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Patent number: 7969951Abstract: A power-saving wireless network, a packet transmitting method for use in the wireless network, and computer readable medium therefor are provided. The wireless network comprises a PAN coordinator, a receiving node and a transferring node. When the transmitting node has a packet planed to be transmitted to the receiving node which is in a sleep mode, the packet is alternatively transmitted to the PAN coordinator. As soon as the receiving node wakes from the sleep mode, all packets are transmitted to the receiving node from the PAN coordinator. After the packets are all successfully transmitted, the receiving node turns back to the sleep mode subsequently. Thereby, the performance of the wireless network would not be restricted to the sleep period and memory capacity. Thus, the nodes in the wireless network would greatly facilitate saving power.Type: GrantFiled: June 30, 2006Date of Patent: June 28, 2011Assignee: Institute for Information IndustryInventors: Yung-Chih Liu, Shih-Hung Liu, Ming-Jer Tsai
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Patent number: 7829333Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: GrantFiled: May 22, 2006Date of Patent: November 9, 2010Assignees: The Johns Hopkins University School of Medicine, Baylor College of MedicineInventors: Philip A. Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
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Publication number: 20070237122Abstract: A power-saving wireless network, a packet transmitting method for use in the wireless network, and computer readable medium therefor are provided. The wireless network comprises a PAN coordinator, a receiving node and a transferring node. When the transmitting node has a packet planed to be transmitted to the receiving node which is in a sleep mode, the packet is alternatively transmitted to the PAN coordinator. As soon as the receiving node wakes from the sleep mode, all packets are transmitted to the receiving node from the PAN coordinator. After the packets are all successfully transmitted, the receiving node turns back to the sleep mode subsequently. Thereby, the performance of the wireless network would not be restricted to the sleep period and memory capacity. Thus, the nodes in the wireless network would greatly facilitate saving power.Type: ApplicationFiled: June 30, 2006Publication date: October 11, 2007Applicant: INSTITUTE FOR INFORMATION INDUSTRYInventors: Yung-Chih Liu, Shih-Hung Liu, Ming-Jer Tsai
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Publication number: 20060211114Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: ApplicationFiled: May 22, 2006Publication date: September 21, 2006Inventors: Philip Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
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Patent number: 7049090Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: GrantFiled: October 1, 2003Date of Patent: May 23, 2006Assignees: The Johns Hopkins University School of Medicine, Baylor College of MedicineInventors: Philip A. Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
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Patent number: 6733971Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: GrantFiled: August 21, 2001Date of Patent: May 11, 2004Assignees: Baylor College of Medicine, The Johns Hopkins University School of MedicineInventors: Philip A. Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
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Publication number: 20040082036Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: ApplicationFiled: October 1, 2003Publication date: April 29, 2004Applicants: THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE, BAYLOR COLLEGE OF MEDICINEInventors: Philip A. Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
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Patent number: 6599698Abstract: The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch for regulating expression in gene therapy and methods of employing the molecular switch in humans, animals, transgenic animals and plants.Type: GrantFiled: December 9, 1998Date of Patent: July 29, 2003Assignee: Baylor College of MedicineInventors: Elisabetta Vegeto, Donald P. McDonnell, Bert W. O'Malley, William T. Schrader, Ming-Jer Tsai
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Publication number: 20030109683Abstract: The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch protein for regulating expression in gene therapy.Type: ApplicationFiled: April 16, 2002Publication date: June 12, 2003Applicants: Baylor College of Medicine, Valentis, Inc.Inventors: Bert W. O'Malley, Ming-Jer Tsai, Sophia Y. Tsai, Harry C. Ledebur, Yaolin Wang, Joseph D. Kittle
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Publication number: 20020182698Abstract: The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch protein for regulating expression in gene therapy.Type: ApplicationFiled: April 16, 2002Publication date: December 5, 2002Applicant: Baylor College of MedicineInventors: Bert W. O'Malley, Ming-Jer Tsai, Sophia Y. Tsai, Harry C. Ledebur, Yaolin Wang, Joseph D. Kittle
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Publication number: 20020147327Abstract: The present invention provides modified proteins of steroid hormone receptors. These mutated proteins are useful as gene medicines. In particular, these mutated proteins are useful for regulating expression of genes in gene therapy. In addition, the present invention provides plasmids encoding for the desired mutated steroid hormone receptor proteins, as well as cells transfected with those plasmids.Type: ApplicationFiled: July 25, 2001Publication date: October 10, 2002Inventors: Bert W. O'Malley, Ming-Jer Tsai, Sophia Y. Tsai, Harry C. Ledebur, Yaolin Wang, Joseph D. Kittle
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Publication number: 20020102646Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: ApplicationFiled: August 21, 2001Publication date: August 1, 2002Applicant: Baylor College of MedicineInventors: Philip A. Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
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Patent number: 6416998Abstract: The present invention provides mutated proteins of steroid hormone receptors. These mutated proteins are useful as gene medicines. In particular, these mutated proteins are useful for regulating expression of genes in gene therapy. In addition, the present invention provides plasmids encoding for the desired mutated steroid hormone receptor proteins, as well as cells transfected with those plasmids.Type: GrantFiled: June 7, 1995Date of Patent: July 9, 2002Assignees: Baylor College of Medicine, Valentis, Inc.Inventors: Bert W. O'Malley, Ming-Jer Tsai, Harry C. Ledebur, Jr., Joseph D. Kittle, Jr.
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Patent number: 6380373Abstract: The present invention relates to SRC-1 polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for enhancing and inhibiting transcription by providing SRC-1 polypeptides or fragments thereof to a cell.Type: GrantFiled: August 21, 1996Date of Patent: April 30, 2002Assignee: Baylor College of MedicineInventors: Bert O'Malley, Ming-Jer Tsai, Sophia Y. Tsai, Sergio Onate
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Patent number: 6277566Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.Type: GrantFiled: February 13, 1998Date of Patent: August 21, 2001Inventors: Phillip A. Beachy, Ming-Jer Tsai, Sophia Y. Tsai, Venkatesh Krishnan, Chen-Huan Chen
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Patent number: 5935934Abstract: The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch for regulating expression in gene therapy and methods of employing the molecular switch in humans, animals, transgenic animals and plants.Type: GrantFiled: May 30, 1995Date of Patent: August 10, 1999Assignee: Baylor College of MedicineInventors: Elisabetta Vegeto, Donald P. McDonnell, Bert W. O'Malley, William T. Schrader, Ming-Jer Tsai
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Patent number: 5874534Abstract: The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch for regulating expression in gene therapy and methods of employing the molecular switch in humans, animals, transgenic animals and plants.Type: GrantFiled: June 6, 1995Date of Patent: February 23, 1999Assignee: Baylor College of MedicineInventors: Elisabetta Vegeto, Donald P. McDonnell, Bert W. O'Malley, William T. Schrader, Ming-Jer Tsai
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Patent number: 5849477Abstract: Multiple methods for measuring the COUP-TF system, including: a method to measure the level of COUP-TF by combining antibodies with biological samples and measuring the resultant antibody/COUP-TF complex; the binding of COUP-TF to promoters by combining biological samples with COUP-TF binding oligonucleotides and measuring the resultant complex or gene synthesis; and a method to measure COUP-TF inducable promoters by combining native COUP-TF with nuclear extracts of biological samples and measuring the resultant complexes. The methods when applied to human biological samples can detect diabetes due to COUP-TF or promoter defects. In addition to the methods for measuring the COUP-TF system and associated diseases, there are also the polyclonal and monoclonal antibodies necessary for the methods. These bind to at least one immunoreactive site on COUP-TF. Furthermore, there is a DNA clone containing the genetic coding regions of the COUP-TF protein.Type: GrantFiled: March 16, 1992Date of Patent: December 15, 1998Assignee: Baylor College of MedicineInventors: Bert William O'Malley, Ming-Jer Tsai, Lee-Ho Wang, Sophia Yang Tsai