Abstract: An electronic device is provided. The electronic device includes a first substrate, an insulating layer, a first conductive layer and a second conductive layer. The insulating layer is overlapped with the first substrate. The second conductive layer contacts with the first conductive layer. The first conductive layer and the second conductive layer are disposed between the first substrate and the insulating layer. The second conductive layer is disposed between the first conductive layer and the insulating layer. Moreover, a thermal expansion coefficient of the second conductive layer is between a thermal expansion coefficient of the first conductive layer and a thermal expansion coefficient of the insulating layer.

Abstract: Described herein are compositions (e.g. cells and transgenic animals) and methods relating to engineered Ig loci that permit expression of particular antibodies or antibody segments while still permitting recombination and/or maturation process for antibody optimization.

Abstract: A probiotic composition for improving an effect of a chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is disclosed in the present disclosure. The probiotic composition comprises an effective amount of Lactobacillus paracasei GMNL-133, an effective amount of Lactobacillus reuteri GMNL-89, and a pharmaceutically acceptable carrier, wherein the Lactobacillus paracasei GMNL-133 was deposited in the China Center for Type Culture Collection on Sep. 26, 2011 under an accession number CCTCC NO. M 2011331, and the Lactobacillus reuteri GMNL-89 was deposited in the China Center for Type Culture Collection on Nov. 19, 2007 under an accession number CCTCC NO. M 207154. A method for improving the effect of the chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is further disclosed in the present disclosure.

Abstract: The present invention belongs to the field of mechanical transmission technology, and proposes a non-orthogonal elliptical toroidal worm gear pair, including an involute cylindrical gear and an elliptical toroidal worm formed by a primary envelope of the involute cylindrical gear; both adopt spatial non-orthogonal transmission, and the shaft angle satisfies the self-locking condition and the restriction condition of minimum tooth top width; the toroidal generatrix of the elliptical toroidal worm is elliptical, which can increase the number of meshing teeth and the total length of instantaneous contact line. A non-orthogonal elliptical toroidal worm gear pair proposed in this invention has the characteristics of toroidal worm drive and can realize the whole facewidth of the gear to participate in the meshing drive.

Abstract: The present disclosure provides a method for preparing a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors, the composition prepared by the method, and use of the composition for treating arthritis. The composition of the present disclosure achieves the effect of treating arthritis through various efficacy experiments.

Abstract: The present invention relates to a method for preparing a modified stem cell, including the following steps: a cell culture step: culturing stem cells in a first culture medium of a culture dish at a predetermined cell density, and removing the first culture medium after a first culture time to obtain a first cell intermediate; an activity stimulation step: preserving the first cell intermediate in a freezing container having a cell cryopreservation solution, and performing a constant temperature stimulation treatment or a variable temperature stimulation treatment for at least more than 1 day; and a product collection step: after completing the activity stimulation step, placing the freezing container in an environment at a thawing temperature for thawing, and then removing the cell cryopreservation solution to obtain the modified stem cell. The modified stem cell can release at least one or more of IL-4, IL-5, IL-13, G-CSF, Fractalkine, and EGF.

Abstract: The present disclosure provides a method for treating liver cirrhosis by using a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors. The composition of the present disclosure achieves the effect of treating liver cirrhosis through various efficacy experiments.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing conversion path performance measures and reports. In one aspect, user interaction data are obtained, were the user interaction data specify user interactions for a plurality of conversions. User interactions that are associated with each conversion are selected from the user interaction data, where the associated user interactions for each conversion are user interactions with a converting user during the conversion cycle for the conversion. Using the user interaction data for the selected user interactions, a quantity of user interactions that are associated with each conversion and occurred during the conversion cycle for the conversion are determined. In turn, conversion path performance measures are computed and reports specifying the conversion path performance measures are generated.

Abstract: The present disclosure provides a bracewear for spinal correction and a system for posture training. The system for posture training involves both active and passive corrective forces by using the bracewear and a biofeedback system to address the spinal correction, which can eliminate the adversity of conventional hard braces and reduce the psychological and physiological barriers to treatment.

Abstract: A liquid-cooling device includes multiple water blocks and at least one connection tube. Each of the water blocks has a water incoming end, a water outgoing end and a water-receiving space in communication with the water incoming end and the water outgoing end. The connection tube is disposed between each two water blocks. Two ends of the connection tube are respectively connected with the water incoming end of one of the two water blocks and the water outgoing end of the other water block, whereby the water-receiving spaces of the two water blocks communicate with each other via the connection tube. The connection tube has at least one bellows section between two ends of the connection tube. The liquid-cooling device solves the problems of the conventional liquid-cooling device that when the water block is welded, thermal deformation is produced to cause tolerance and the manufacturing cost is higher.

Abstract: A semiconductor device includes a substrate, a dielectric layer disposed over the substrate, and an interconnect structure extending through the dielectric layer. The dielectric layer includes a low-k dielectric material which includes silicon carbonitride having a carbon content ranging from about 30 atomic % to about 45 atomic %. The semiconductor device further includes a thermal dissipation feature extending through the dielectric layer and disposed to be spaced apart from the interconnect structure.

Abstract: A TEE system that includes a first platform that runs a first TEE, a second platform that runs a second TEE, and a merging unit that is adapted to merge a first output from the first TEE of the first platform, with a second output from the second TEE of the second platform, so as to form an output of the TEE system. The first TEE and the second TEE are based on different implementations. In this way, the security of the system is improved, as a malicious actor even be able to access “t” machines, still would not be able to retrieve the secret unless there are multiple exploitable TEE vulnerabilities on all executing TEE platforms at the same time.

Abstract: Disclosed in the present invention is an optimized cell transplant. The optimized cell transplant is formed by performing gene induction and modification on a mesenchymal stem cell in the form of a small molecule and protein composition. The expression levels of CD200 gene, Galectin-9 gene and VISTA gene can be increased synchronously after cell culture. Vector virus infection and plasmid transfection are not required in the cell preparation process, so that high biological safety and great clinical application value of cells are achieved.

Abstract: A light source module includes a first light source and a second light source. The first light source is configured for emitting a first light having a first wavelength, and the first light includes a first part and a second part. The second light source is configured for emitting a second light having a second wavelength. The second light source includes a first wavelength conversion layer, and the first wavelength conversion layer is configured for converting the first light into the second light. One of the first part and the second part is incident to the first wavelength conversion layer, and the other of the first part and the second part is not incident to the first wavelength conversion layer.

Abstract: A ferroelectric memory device and a semiconductor die are provided. The ferroelectric memory device includes a gate electrode; a channel layer, overlapped with the gate electrode; source/drain contacts, in contact with separate ends of the channel layer; a ferroelectric layer, lying between the gate electrode and the channel layer; and a first insertion layer, extending in between the ferroelectric layer and the channel layer, and comprising a metal carbonitride or a metal nitride.

Abstract: The present disclosure relates to chimeric antigen receptors (CARs), which bind to Globo series antigens (e.g. Globo H, SSEA-3 or SSEA-4), including an antigen-binding fragment (Fab) or a single-chain variable fragment (scFv). Further, the present methods are also provided for administering CARs to a subject in an amount effective to inhibit cancer cells.

Abstract: Devices and methods for forming a chip package structure including a package substrate, a first adhesive layer attached to a top surface of the package substrate, and a beveled stiffener structure attached to the package substrate. The beveled stiffener structure may include a bottom portion including a tapered top surface, in which a bottom surface of the bottom portion is in contact with the first adhesive layer, a second adhesive layer attached to the tapered top surface, and a top portion including a tapered bottom surface, in which the tapered bottom surface is in contact with the second adhesive layer. The tapered top surface and the tapered bottom surface have a taper angle between 5 degrees and 60 degrees with respect to a top surface of the package substrate.

Abstract: A large gear involute artifact assembled with mandrel used as physical datum of precision traceability and measurement transmission for large gear involute is proposed. The artifact comprises a large gear involute artifact stripe, a mandrel, a backing plate, a counterweight shaft, an adjustable counterweight ring, the adjustable screws of counterweight, the connecting screws for backing plate, the connecting screws for artifact and an eccentric multi-ball bearing. The structure and the rolled length of the large gear involute artifact assembled with mandrel fit the basic requirements of class-1 accuracy in the national standard of gear involute artifact GB/T 6467-2010 in China. It has advantages of long rolled length, adjustable center of mass, uniform datum, compact structure, and portability. It adopts lightweight design, which can be installed and transported by one person manually, and is suitable for the structural design of large gear involute artifact with base-circle diameter greater than 500 mm.

Abstract: A pure-rolling generating measurement method and device for gear helix artifact is proposed, which use a dividing table to accurately control the linear rail slide block assembly component to rotate according to the helix angle of different base circle. The height of the measuring point is the installation height of the working plane of generating rails, so as to ensure that the measuring point is always located on the dividing cylindrical surface of the gear helix artifact. When the gear helix artifact does pure-rolling motion, the slide block performs high-precision linear motion on the working surface of two fixed rails; the pure-rolling motion is proportional to the high-precision linear motion, so that the inductor micro-displacement probe can complete the measurement of the helix deviations of the gear helix artifact with different base circle helix angle.

Abstract: A generating device based on friction drive for gear involute artifact with long-rolled path length by rolling method is proposes. The device includes a roller component, rail component and friction-driven component, wherein the roller component consists of a gear involute artifact with long rolled length, a mandrel, a multi-ball bearing for gear involute artifact, the base-circle plates, the parallel sleeves, a multi-ball bearing, the plain washers, the cross washers, and the locking nuts; the rail component consists of a foundation, a location baffle for base-circle plates, rails, the baffles, a location baffle for rail, copper washers, the connecting screws and the set screws of the rail; and the friction-driven component consists of a friction block, a motorized linear sliding table, a vertical sliding table, a vertical foundation and an adapter. It has good market application prospect and popularization value.