Patents by Inventor Mingda Bi

Mingda Bi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compounds and their uses
    Patent number: 11884630
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Grant
    Filed: June 8, 2022
    Date of Patent: January 30, 2024
    Assignee: CYTOKINETICS, INC.
    Inventors: Mingda Bi, Robert Kuehl
  • OMECAMTIV MECARBIL TABLET
    Publication number: 20230090391
    Abstract: Provided herein are tablet formulations comprising a core comprising omecamtiv mecarbil, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable hydrate of a pharmaceutically acceptable salt thereof; a filler; a binder; a glidant; and a lubricant; and a film coating on the core, the film coating comprising a modified-release polymer and a pore former. Also provided is a process for making a tablet formulation and a method of treating cardiovascular conditions, such as heart failure, using the tablet formulation.
    Type: Application
    Filed: February 10, 2021
    Publication date: March 23, 2023
    Inventors: Mingda BI, Yuan-Hon KIANG, Hao LOU
  • HETEROCYCLIC COMPOUNDS AND THEIR USES
    Publication number: 20220298114
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Application
    Filed: June 8, 2022
    Publication date: September 22, 2022
    Inventors: Mingda BI, Robert KUEHL
  • Heterocyclic compounds and their uses
    Patent number: 11384053
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: July 12, 2022
    Assignee: CYTOKINETICS, INC.
    Inventors: Mingda Bi, Robert Kuehl
  • HETEROCYCLIC COMPOUNDS AND THEIR USES
    Publication number: 20200277261
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Application
    Filed: September 23, 2019
    Publication date: September 3, 2020
    Inventors: Mingda Bi, Robert Kuehl
  • Heterocyclic compounds and their uses
    Patent number: 10421726
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: September 24, 2019
    Assignee: AMGEN INC.
    Inventors: Mingda Bi, Robert Kuehl
  • PEDIATRIC FORMULATION
    Publication number: 20190216737
    Abstract: The present invention is directed to pediatric formulation of (R)—N-[-1-(1-naphthyl)-ethyl]-343-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride (hereinafter referred to as Cinacalcet HCl) and method of administering the same.
    Type: Application
    Filed: September 7, 2018
    Publication date: July 18, 2019
    Inventors: Mingda Bi, Fernando Alvarez-Nunez, Francisco Javier Alvarez
  • Method and apparatus for accessing demilitarized zone host on local area network
    Patent number: 10171418
    Abstract: A method for accessing a demilitarized zone (DMZ) host in a local access network (LAN) includes: configuring a mapping relationship between public IP addresses obtained from a wide area network (WAN) side and private IP addresses of demilitarized zone hosts at a LAN side; after receiving an access request sent by a client at the WAN side, modifying a destination IP address in the access request to the private IP address of a corresponding demilitarized zone host at the LAN side according to the configured mapping relationship, and sending the modified access request to the demilitarized zone host; receiving a reply message returned by the demilitarized zone host, modifying a source IP address contained in the reply message to a public IP address of a client at the WAN side, and sending the modified reply message to the WAN side. The present document also discloses a corresponding apparatus.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: January 1, 2019
    Assignee: XI'AN ZHONGXING NEW SOFTWARE CO., LTD
    Inventor: Mingda Bi
  • HETEROCYCLIC COMPOUNDS AND THEIR USES
    Publication number: 20180273479
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Application
    Filed: March 20, 2018
    Publication date: September 27, 2018
    Inventors: Mingda Bi, Robert Kuehl
  • Heterocyclic compounds and their uses
    Patent number: 9951015
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 24, 2018
    Assignee: AMGEN INC.
    Inventors: Mingda Bi, Robert Kuehl
  • PEDIATRIC FORMULATION
    Publication number: 20180098940
    Abstract: The present invention is directed to pediatric formulation of (R)-N-[-1-(1-naphthyl)-ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride (hereinafter referred to as Cinacalcet HC1) and method of administering the same.
    Type: Application
    Filed: May 24, 2017
    Publication date: April 12, 2018
    Inventors: MINGDA BI, FERNANDO ALVAREZ-NUNEZ, FRANCISCO JAVIER ALVAREZ
  • Method And Apparatus For Accessing Demilitarized Zone Host On Local Area Network
    Publication number: 20150319134
    Abstract: A method for accessing a demilitarized zone (DMZ) host in a local access network (LAN) includes: configuring a mapping relationship between public IP addresses obtained from a wide area network (WAN) side and private IP addresses of demilitarized zone hosts at a LAN side; after receiving an access request sent by a client at the WAN side, modifying a destination IP address in the access request to the private IP address of a corresponding demilitarized zone host at the LAN side according to the configured mapping relationship, and sending the modified access request to the demilitarized zone host; receiving a reply message returned by the demilitarized zone host, modifying a source IP address contained in the reply message to a public IP address of a client at the WAN side, and sending the modified reply message to the WAN side. The present document also discloses a corresponding apparatus.
    Type: Application
    Filed: September 17, 2013
    Publication date: November 5, 2015
    Applicant: ZTE CORPORATION
    Inventor: Mingda BI
  • HETEROCYCLIC COMPOUNDS AND THEIR USES
    Publication number: 20140309235
    Abstract: Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 16, 2014
    Applicants: CYTOKINETICS, INC., AMGEN INC.
    Inventors: Mingda Bi, Robert Kuehl
  • PEDIATRIC FORMULATION
    Publication number: 20140147497
    Abstract: The present invention is directed to pediatric formulation of (R)-N-[-1-(1-naphthyl)-ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride (hereinafter referred to as Cinacalcet HCl) and method of administering the same.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 29, 2014
    Applicant: AMGEN INC.
    Inventors: Mingda Bi, Fernando Alvarez-Nunez, Francisco Javier Alvarez