Patents by Inventor Mingiang Zhang

Mingiang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-Mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block
    Patent number: 6670340
    Abstract: Disclosed is a 6-mercapto-cyclodextrin derivative having general formula (I) wherein m is 0-7 and n is 1-8 and m+n=7 or 8; R is (C1-6)alkylene, optionally substituated with 1-3 OH groups, or (CH2)o-phenylene-(CH2)p—; o and p are independently 0-4; X is COOH, CONHR1, NHCOR2, SO2OH, PO(OH)2, O(CH2—CH2—O)q—H, OH or tetrazol-5-yl; R1 is H or (C1-3)alkyl; R2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof. The 6-mercaptocyclodextrin derivative is highly suitable for use in the reversal of drug-induced neuromuscular block.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: December 30, 2003
    Assignee: Akzo Nobel
    Inventors: Mingiang Zhang, Ronald Palin, David Jonathan Bennett
  • 6-mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block
    Patent number: RE44733
    Abstract: Disclosed is a 6-mercapto-cyclodextrin derivative having general formula (I) wherein m is 0-7 and n is 1-8 and m+n=7 or 8; R is (C1-6)alkylene, optionally substituated with 1-3 OH groups, or (CH2)o-phenylene-(CH2)p—; o and p are independently 0-4; X is COOH, CONHR1, NHCOR2, SO2OH, PO(OH)2, O(CH2—CH2—O)q—H, OH or tetrazol-5-yl; R1 is H or (C1-3)alkyl; R2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof. The 6-mercaptocyclodextrin derivative is highly suitable for use in the reversal of drug-induced neuromuscular block.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: January 28, 2014
    Assignee: Merck Sharp & Dohme B.V.
    Inventors: Mingiang Zhang, Ronald Palin, Jonathan Bennett