Abstract: Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.

Abstract: Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.

Abstract: This invention belongs to the nanotechnology field, and discloses a nano drug delivery system with polyethyleneglycol-poly(lactic-co-glycolic acid)-poly-L-lysine (PEG-PLGA-PLL) polymer as the skeleton. The carrier can have the function of passive targeting through control of the carrier particle size. The polymer skeleton is modified through introducing side chains and specific targeting groups, so as to adjust and improve the carrier performance, and enable the carrier to have the function of active targeting. Such carrier material also has the functions of transporting active substances, tumor treatment and diagnosis, ultrasonic contrast, reversing or reducing drug resistance and so on.

Abstract: A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help rank the objects in a search result to improve search performance. The method may be used in vertical search of objects such as published articles, products and images that lack explicit URLs and anchor text information.

Abstract: A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help rank the objects in a search result to improve search performance. The method may be used in vertical search of objects such as published articles, products and images that lack explicit URLs and anchor text information.

Abstract: A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help ranking the objects in a search result to improve search performance. Method may be used in vertical search of objects such as published articles, products and images that lack explicit URL and anchor text information.

Abstract: A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help ranking the objects in a search result to improve search performance. Method may be used in vertical search of objects such as published articles, products and images that lack explicit URL and anchor text information.

Abstract: Disclosed herein are processes for detecting the location of an interface between phases. In one embodiment, the process comprises: introducing a reaction mixture into a vessel wherein the reaction mixture is the product of an at least two phase interfacial reaction, and a difference in densities between at least two of the phases is less than or equal to about 1 g/cc, separating the reaction mixture into the phases with an interface located therebetween, measuring electrical inductance of the reaction mixture at different latitudinal locations; and determining the location of the interface.

Abstract: Disclosed herein are processes for detecting the location of an interface between phases. In one embodiment, the process comprises: introducing a reaction mixture into a vessel wherein the reaction mixture is the product of an at least two phase interfacial reaction, and a difference in densities between at least two of the phases is less than or equal to about 1 g/cc, separating the reaction mixture into the phases with an interface located therebetween, measuring electrical inductance of the reaction mixture at different latitudinal locations; and determining the location of the interface.

Abstract: This invention relates to an economical and efficient process for purifying a reaction mixture obtained in a two-phase interfacial reaction for the preparation of polycarbonate. More particularly, the method of the invention provides for separating the reaction mixture into an organic phase, which includes the desired polycarbonate and undesirable impurities, and an aqueous phase. The organic phase is further purified by using a plate decanter in combination with coalescence and centrifugation.

Abstract: This invention relates to a method for purifying a polycarbonate resin solution resulting from an interfacial polymerization process. More particularly, this invention provides for the use of at least one static mixer to facilitate separation of the catalyst used to prepare the polycarbonate from the polycarbonate resin solution.