Patents by Inventor Mitchell Gross

Mitchell Gross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anticoagulant agents useful in treatment of thrombosis
    Publication number: 20070003553
    Abstract: Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
    Type: Application
    Filed: August 11, 2005
    Publication date: January 4, 2007
    Inventors: Michael Blackburn, William Church, Giora Feuerstein, Mitchell Gross, Andrew Nichols, Eduardo Padlan, Arunbhai Patel, Daniel Sylvester
  • Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
    Publication number: 20060263853
    Abstract: Chimeric and humanized IL4 A MAbs derived from affinity MAbs, pharmaceutical compositions containing same, and methods of treatment are provided.
    Type: Application
    Filed: July 26, 2006
    Publication date: November 23, 2006
    Inventors: Stephen Holmes, Mitchell Gross, Daniel Sylvester
  • Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
    Publication number: 20060029594
    Abstract: Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
    Type: Application
    Filed: October 20, 2005
    Publication date: February 9, 2006
    Inventors: Robert Ames, Edward Appelbaum, Irwin Chaiken, Richard Cook, Mitchell Gross, Stephen Holmes, Lynette McMillan, Timothy Theisen
  • Human monoclonal antibody
    Publication number: 20050175986
    Abstract: This invention relates to novel human monoclonal antibodies (mAbs) and to the genes encoding same. More specifically, this invention relates to human monoclonal antibodies specifically reactive with an epitope of the fusion (F) protein of Respiratory Syncytial Virus (RSV). Such antibodies are useful for the therapeutic and/or prophylactic treatment of RSV infection in human patients, particularly infants and young children.
    Type: Application
    Filed: June 13, 2003
    Publication date: August 11, 2005
    Inventors: Mitchell Gross, Raymond Sweet, Geraldine Taylor
  • Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
    Publication number: 20050002959
    Abstract: Chimeric and humanized IL4 MAbs derived from affinity MAbs, pharmaceutical compositions containing same, and methods of treatment are provided.
    Type: Application
    Filed: November 26, 2003
    Publication date: January 6, 2005
    Inventors: Stephen Holmes, Mitchell Gross, Daniel Sylvester
  • Human marco scavenger receptor
    Patent number: 6197931
    Abstract: Human Marco scavenger receptor polypeptides (HMarcoSR) and DNA (RNA) encoding such HMarcoSR and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such HMarcoSR for the treatment of various cardivascular disorders, gangrene, and loss of function in the extremeties. Antagonists against such HMarcoSR and their use as a therapeutic to treat of various cardivascular disorders, gangrene, and loss of function in the extremeties are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the HMarcoSR and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: March 6, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Nabil Elshourbagy, John Adamou, Mitchell Gross, Paul Lysko
  • Human marco scavenger receptor
    Patent number: 5916766
    Abstract: Human Marco scavenger receptor polypeptides (HMarcoSR) and DNA (RNA) encoding such HMarcoSR and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such HMarcoSR for the treatment of various cardivascular disorders, gangrene, and loss of fuunction in the extremeties. Antagonists against such HMarcoSR and their use as a therapeutic to treat various cardivascular disorders, gangrene, and loss of fuunction in the extremeties are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the HMarcoSR and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: February 4, 1997
    Date of Patent: June 29, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Nabil Elshourbagy, John Adamou, Mitchell Gross, Paul Lysko