Patents by Inventor Mitchell S. Albert
Mitchell S. Albert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 6845262Abstract: A method of imaging using magnetic resonance includes administering hyperpolarized noble gas to a subject in a region to be imaged, applying a magnetic field of a magnitude between about 0.0001 Tesla and about 0.1 Tesla to the subject at least in the region of the subject to be imaged, detecting a spatial distribution of magnetic resonance signals of the hyperpolarized noble gas in the subject, and producing a representation of the spatial distribution.Type: GrantFiled: March 27, 2001Date of Patent: January 18, 2005Assignee: The Brigham and Women's Hospital, Inc.Inventors: Mitchell S. Albert, Dilip Balamore, Arvind K. Venkatesh
-
Patent number: 6593144Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: December 19, 2000Date of Patent: July 15, 2003Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
-
Patent number: 6471747Abstract: The present invention is directed to a procedure for recycling used gasses and to devices that can be use to accomplish this recycling.Type: GrantFiled: June 20, 2000Date of Patent: October 29, 2002Assignees: The Brigham and Women's Hospital, Inc., Trustees of Boston UniversityInventors: Arvind Venkatesh, Mitchell S. Albert, Jeffrey J. Spiegelman
-
Patent number: 6467479Abstract: The present invention uses a ventilator and a series of valves to deliver a special gas into a patient. The present invention finds use in the field of MRI imaging. Attached to the tube extending from the ventilator to the patient is attached a first valve. This valve alternately connects the patient to the ventilator then to a supply of the special gas. Between the first valve and the supply of gas is a second valve, which controls the pressure between the first valve and the second valve caused by the special gas. The supply of special gas is connected to the second valve. A flow regulator controls the rate at which the special gas enters the patient. A computer is also attached to the ventilator and valves to synchronize the opening and closing of the valves and the operation of the ventilator with the patient's respiratory cycles.Type: GrantFiled: October 7, 1999Date of Patent: October 22, 2002Assignee: The Brigham and Women's Hospital, Inc.Inventors: Mitchell S. Albert, Arvind K. Venkatesh, Charles F. Ward, III
-
Publication number: 20010037063Abstract: A method of imaging using magnetic resonance includes administering hyperpolarized noble gas to a subject in a region to be imaged, applying a magnetic field of a magnitude between about 0.0001 Tesla and about 0.1 Tesla to the subject at least in the region of the subject to be imaged, detecting a spatial distribution of magnetic resonance signals of the hyperpolarized noble gas in the subject, and producing a representation of the spatial distribution.Type: ApplicationFiled: March 27, 2001Publication date: November 1, 2001Inventors: Mitchell S. Albert, Dilip Balamore, Arvind K. Venkatesh
-
Patent number: 6241966Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: March 18, 1998Date of Patent: June 5, 2001Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
-
Publication number: 20010000726Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: ApplicationFiled: December 19, 2000Publication date: May 3, 2001Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
-
Patent number: 6123919Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: June 24, 1999Date of Patent: September 26, 2000Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
-
Patent number: 5789921Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: June 7, 1995Date of Patent: August 4, 1998Assignees: The Research Foundation of State University of New York, The Trustees of Princeton UniversityInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
-
Patent number: 5785953Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: June 17, 1996Date of Patent: July 28, 1998Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
-
Patent number: 5545396Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: April 8, 1994Date of Patent: August 13, 1996Assignees: The Research Foundation of State University of New York, The Trustees of Princeton University Office of Research and Project AdministrationInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia