Patents by Inventor Mitsuhiro Ebara

Mitsuhiro Ebara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained drug release sheet for treating nerve injury
    Patent number: 11324704
    Abstract: Provided is a sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet comprising a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: May 10, 2022
    Assignees: OSAKA UNIVERSITY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Hiroyuki Tanaka, Kiyoshi Okada, Hideki Yoshikawa, Koji Suzuki, Mitsuhiro Ebara
  • SUSTAINED DRUG RELEASE SHEET FOR TREATING NERVE INJURY
    Publication number: 20210205234
    Abstract: A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
    Type: Application
    Filed: February 1, 2021
    Publication date: July 8, 2021
    Applicants: OSAKA UNIVERSITY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Hiroyuki TANAKA, Kiyoshi OKADA, Hideki YOSHIKAWA, Koji SUZUKI, Mitsuhiro EBARA
  • NONWOVEN FABRIC, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ELECTROSPINNING
    Publication number: 20210140081
    Abstract: A non-woven fabric including fibers including an aliphatic polyester that has at least two maximum values in a molecular weight distribution thereof, wherein the fibers have a fiber diameter falling within the range of 100 to 3000 nm. The non-woven fabric of the present invention has excellent biodegradability.
    Type: Application
    Filed: July 9, 2019
    Publication date: May 13, 2021
    Applicants: NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Koichiro UTO, Mitsuhiro EBARA, Mitsuru NAIKI, Takafumi KONISHI, Hitoshi YAMAMOTO
  • SUSTAINED DRUG RELEASE SHEET FOR TREATING NERVE INJURY
    Publication number: 20190083415
    Abstract: Provided is a sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet comprising a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
    Type: Application
    Filed: March 6, 2017
    Publication date: March 21, 2019
    Applicants: OSAKA UNIVERSITY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Hiroyuki TANAKA, Kiyoshi OKADA, Hideki YOSHIKAWA, Koji SUZUKI, Mitsuhiro EBARA
  • Blood purification membrane, method for manufacturing blood purification membrane, and dialysis device
    Patent number: 10232321
    Abstract: A blood purification membrane capable of adsorbing creatinine which is a uremic toxin in the blood and purifying the blood, the blood purification membrane including fibers and particles adhered to the aforementioned fibers, wherein the aforementioned fibers are composed of a polymer insoluble in water, the aforementioned particles contain SiO2 and Al2O3, and pores capable of incorporating at least a portion of the aforementioned uremic toxin are provided in the aforementioned particles.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: March 19, 2019
    Assignee: NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Mitsuhiro Ebara, Koki Namekawa, Takao Aoyagi
  • BLOOD PURIFICATION MEMBRANE, METHOD FOR MANUFACTURING BLOOD PURIFICATION MEMBRANE, AND DIALYSIS DEVICE
    Publication number: 20160199789
    Abstract: A blood purification membrane capable of adsorbing creatinine which is a uremic toxin in the blood and purifying the blood, the blood purification membrane including fibers and particles adhered to the aforementioned fibers, wherein the aforementioned fibers are composed of a polymer insoluble in water, the aforementioned particles contain SiO2 and Al2O3, and pores capable of incorporating at least a portion of the aforementioned uremic toxin are provided in the aforementioned particles.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 14, 2016
    Applicant: National Institute of Materials Science
    Inventors: Mitsuhiro EBARA, Koki NAMEKAWA, Takao AOYAGI
  • NANOFIBER HAVING SELF-HEATING PROPERTIES AND BIOLOGICALLY ACTIVE SUBSTANCE RELEASE PROPERTIES, PRODUCTION METHOD FOR SAME, AND NONWOVEN FABRIC HAVING SELF-HEATING PROPERTIES AND BIOLOGICALLY ACTIVE SUBSTANCE RELEASE CAPABILITIES
    Publication number: 20150352209
    Abstract: The invention aims to provide a nanofiber having self-heating properties and biologically active substance release properties, which can release a drug at the same time as self-heating, and can be safely used on a human body without diffusing self-heating nanoparticles, a production method for the same, and a nonwoven fabric having self-heating properties and biologically active substance release capabilities.
    Type: Application
    Filed: January 10, 2014
    Publication date: December 10, 2015
    Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Mitsuhiro EBARA, Takao AOYAGI, Koichiro UTO
  • Stimuli-responsive magnetic nanoparticles and related methods
    Patent number: 8507283
    Abstract: Stimuli-responsive magnetic nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: August 13, 2013
    Assignee: University of Washington
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Jr-iuan Lai, John Hoffman, Mitsuhiro Ebara
  • STIMULI-RESPONSIVE MAGNETIC NANOPARTICLES AND RELATED METHODS
    Publication number: 20110266492
    Abstract: Stimuli-responsive magnetic nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles.
    Type: Application
    Filed: June 15, 2011
    Publication date: November 3, 2011
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Jr-iuan Lai, John Hoffman, Mitsuhiro Ebara
  • Stimuli-responsive magnetic nanoparticles and related methods
    Patent number: 7981688
    Abstract: Stimuli-responsive magnetic nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: July 19, 2011
    Assignee: University of Washington
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Jr-iuan Lai, John Hoffman, Mitsuhiro Ebara
  • STIMULI-RESPONSIVE MAGNETIC NANOPARTICLES AND RELATED METHODS
    Publication number: 20080220531
    Abstract: Stimuli-responsive magnetic nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles.
    Type: Application
    Filed: March 8, 2007
    Publication date: September 11, 2008
    Applicant: Washington, University of
    Inventors: Patrick S. Stayton, Allan S. Hoffman, Jr-iuan Lai, John Hoffman, Mitsuhiro Ebara