Abstract: The present invention establishes a molecular therapy for glycogen storage disease type Ia. The present invention provides an oligonucleotide of 15-30 bases comprising a nucleotide sequence complementary to die cDNA of G6PC gene with c.648G>T mutation, wherein the oligonucleotide comprises a sequence complementary to a region comprising any site between the 82nd to the 92nd nucleotide from the 5? end of exon 5 of the G6PC gene with c.648C>T mutation, a pharmacologically acceptable salt or solvate thereof. Also provided is a pharmaceutical drug comprising the oligonucleotide, a pharmacologically acceptable salt or solvate thereof (e.g., therapeutic drug for glycogen storage disease type Ia).

Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMD A receptor containing the NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I), wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

Abstract: The present invention provides an information providing apparatus including a determining unit configured to determine an added value to be provided to a user of a portable electric power supply device including a storage battery that stores electric power to be supplied to electrical equipment detachably connected, wherein in a case where a kind of the electrical equipment is a specified kind of electrical equipment, the determining unit determines the added value to be provided to the user in such a manner that the added value to be provided to the user is higher than an added value in a case where the kind of the electrical equipment is not the specified kind of electrical equipment.

Abstract: A load estimation device measures a voltage and a current supplied to a load connected to a portable power-supply, obtains a feature amount of the load from the voltage and the current. The device obtains a stored feature amount of each of loads, and related load information indicating a plurality of loads which are used in association with each other. The device estimates a load connected to the power-supply on the basis of the obtained feature amount and a stored feature amount, and predicts a load which is not connected to the power-supply and which is a load related to the estimated load on the basis of the related load information.

Abstract: The present invention provides an information providing apparatus including a determining unit configured to determine an added value to be provided to a user of a portable electric power supply device including a storage battery that stores electric power to be supplied to electrical equipment detachably connected, wherein in a case where a kind of the electrical equipment is a specified kind of electrical equipment, the determining unit determines the added value to be provided to the user in such a manner that the added value to be provided to the user is higher than an added value in a case where the kind of the electrical equipment is not the specified kind of electrical equipment.

Abstract: A power supply system comprises a portable first power supply device and second power supply device. The portable first power supply device has a handle to be gripped by a hand of a user. A supply unit of the portable first power supply comprises an inverter circuit which converts at least a portion of excess power into an alternating current, and supplies to the second power supply device via a second connection unit and a power line, power of the alternating current outputted from the inverter circuit.

Abstract: An information processing apparatus comprises an acquisition unit configured to acquire information according to the usage circumstances of the portable electric generator; an estimation unit configured to estimate a type of an electrical device that is connected, based on a measurement result with respect to a voltage and a current when the portable electric generator supplied electric power that is included in the information according to the usage circumstances; and a calculation unit configured to calculate a rental fee associated with an electric power amount supplied by the portable electric generator at the rental destination, using a billing coefficient corresponding to an electrical device estimated by the estimation unit, and the measurement result.

Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

Abstract: The present invention provides a heterocyclic compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and expected to be useful as an agent for the prophylaxis or treatment of major depression, bipolar disorder, migraine, pain, behavioral and psychological symptoms of dementia and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.

Abstract: In a recoil starter that starts an engine, the recoil starter rotating a drive shaft of the engine using rotation force of a reel through a recoil rope wound around the reel, by the recoil rope being pulled, a ratchet claw is provided on the reel, the ratchet claw pivoting in a radial direction of the reel with rotation of the reel by the recoil rope and then engaging with a pulley provided on the drive shaft, a guide member is provided around a reel shaft, the guide member covering the ratchet claw, the reel shaft being a rotation shaft of the reel, and a rib is provided on the guide member, the rib abutting on the ratchet claw.

Abstract: An information providing device includes: a reception unit configured to receive current location information on a transportable power supply device from the transportable power supply device that supplies power to an electric apparatus detachably connected thereto; an information generation unit configured to generate use place information indicating a place of use of the transportable power supply device based on the received current location information; and a transmission unit configured to transmit the use place information to a service provider's terminal. The reception unit receives information on the electric apparatus connected to the transportable power supply device from the transportable power supply device. The use place information includes information on a type of the electric apparatus connected to the transportable power supply device.

Abstract: An information providing apparatus provides information concerning a lendable electric power supply device. More specifically, the information providing apparatus for providing information via a network in response to a request from a terminal, performs the following processes. The apparatus receives, from the terminal via the network, an information request concerning a lendable electric power supply device configured to supply electric power, acquires information concerning electric power that can be provided by the electric power supply device and a lending price of the electric power supply device by communicating with the electric power supply device via the network. The apparatus further edits, based on the acquired information, information to be provided to the terminal that has issued the information request, and transmits the edited information to the terminal that has issued the information request via the network.

Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMD A receptor containing the NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I), wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

Abstract: A honeycomb structure includes a pillar-shaped honeycomb structure body having a porous partition wall defining a plurality of cells serving as fluid through channel extending from an inflow end face to an outflow end face; and a circumferential wall surrounding the partition wall, wherein in a plane orthogonal to cell extending direction, the honeycomb structure body has a circumferential cell structure, a center cell structure having a cell structure different from the circumferential cell structure, and a boundary wall, the honeycomb structure body has intersection parts of the partition wall, including basic intersection parts and thick intersection parts having a thickness larger than that of the basic intersection parts, the thick intersection parts include at least one of: first thick intersection parts and second thick intersection parts, and in the circumferential cell structure, the intersection parts at least include the circumferential basic intersection parts.

Abstract: A management device is connected to an AC power line provided with a plurality of connection ports, each of which can be connected to an electric device including a power storage unit. The management device includes a measurement unit configured to measure an electric signal on the AC power line, a determination unit configured to determine a type of the electric device connected to the AC power line via a connection port in the plurality of connection ports based on a measurement result of the measurement unit, and a first prediction unit configured to predict an amount of power supply on the AC power line due to discharge of the power storage unit based on a determination result of the determination unit.

Abstract: A load estimating device measures a voltage and a current supplied to a load connected with a generator, calculates a feature amount of the load, senses a remaining amount of fuel, outputs a time during which the load is continuously operable. The device estimates what the load connected with the generator is, based on the calculated feature amount and the feature amounts stored in a storage, and determines the time during which the estimated load is continuously operable, based on a power consumption of the estimated load, and the remaining amount of fuel. The device has a load registration mode for causing the storage to store therein a feature amount of a new load that is not stored in a storage.

Abstract: In a recoil starter that starts an engine, the recoil starter rotating a drive shaft of the engine using rotation force of a reel through a recoil rope wound around the reel, by the recoil rope being pulled, a ratchet claw is provided on the reel, the ratchet claw pivoting in a radial direction of the reel with rotation of the reel by the recoil rope and then engaging with a pulley provided on the drive shaft, a guide member is provided around a reel shaft, the guide member covering the ratchet claw, the reel shaft being a rotation shaft of the reel, and a rib is provided on the guide member, the rib abutting on the ratchet claw.

Abstract: A server acquires a reception amount which is an amount of power that a power supply device received from an engine-driven type generator, converts the reception amount into a virtual currency, transmits, to the power supply device, a money transfer instruction in order to instruct a money transfer, to the engine-driven type generator, of a virtual currency that the conversion unit converted the reception amount into. The power supply device generates a money transfer request in order to, in accordance with the money transfer instruction, performs a money transfer of virtual currency to a virtual currency wallet associated with the engine-driven type generator a virtual currency wallet associated with the server, and transmits the money transfer request to a virtual currency network.