Patents by Inventor Mitsuru Watanuki

Mitsuru Watanuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Sulfamoylbenzoic acid derivatives
    Publication number: 20020049228
    Abstract: 2-Sulfamoylbenzoic acid derivatives of general formula (I): 1
    Type: Application
    Filed: April 27, 2001
    Publication date: April 25, 2002
    Applicant: Kaken Pharmaceuticals
    Inventors: Yoshihiro Ichikawa, Tokiko Nishida, Jun Nakano, Mitsuru Watanuki, Masahiro Suda, Tsutomu Nakamura
  • 2-sulfamoylbenzoic acid derivatives
    Patent number: 6376671
    Abstract: 2-Sulfamoylbenzoic acid derivatives of general formula (I): which have both an antagonistic effect on the leukotriene D4 receptor and an antagonistic effect on the thromboxane A2 receptor and salts thereof, pharmaceuticals, anti-allergic agents and leukotriene-thromboxane A2 antagonistic agents containing them as an active ingredient.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: April 23, 2002
    Assignee: Kaken Pharmaceutical Co., Ltd.
    Inventors: Yoshihiro Ichikawa, Tokiko Nishida, Jun Nakano, Mitsuru Watanuki, Masahiro Suda, Tsutomu Nakamura
  • 2-sulfamoylbenzoic acid derivatives
    Patent number: 6255321
    Abstract: 2-Sulfamoylbenzoic acid derivatives of general formula (I): which have both an antagonistic effect on the leukotriene D4 receptor and an antagonistic effect on the thromboxane A2 receptor and salts thereof, pharmaceuticals, anti-allergic agents and leukotrienethromboxane A2 antagonistic agents containing them as an active ingredient.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: July 3, 2001
    Assignee: Kaken Pharmaceutical Co., Ltd.
    Inventors: Yoshihiro Ichikawa, Tokiko Nishida, Jun Nakano, Mitsuru Watanuki, Masahiro Suda, Tsutomu Nakamura
  • Therapy of respiratory tract diseases using basic fibroblast growth factor
    Patent number: 5514652
    Abstract: The present invention relates to a preparation for the therapy of respiratory tract diseases which contains a basic fibroblast growth factor and/or a homologue thereof as an active ingredient, a preparation for the therapy of respiratory tract diseases which contains a human basic fibroblast growth factor and/or a homologue thereof, produced by microorganisms or cultured cells prepared by genetic recombination, as an active ingredient, and a method for the therapy of respiratory tract diseases by administering any one of these preparations.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: May 7, 1996
    Assignee: Kaken Pharmaceutical Co., Ltd.
    Inventors: Mitsuru Watanuki, Tsutomu Nakamura, Masaru Ogawa
  • Piperidine compounds which have useful pharmaceutical activity
    Patent number: 5190959
    Abstract: A piperidine derivative having the formula (I): ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different from each other, are (i) a not-substituted phenyl group or a phenyl group substituted by a halogen atom, trifluoromethyl group, a C.sub.1-5 alkyl group or a C.sub.1-5 alkoxyl group, (ii) a C.sub.3-7 cycloalkyl group, (iii) pyridyl group or (iv) thienyl group, R.sup.3 is (i) hydrogen atom, (ii) a halogen atom, (iii) a C.sub.1-4 alkyl group or (iv) a C.sub.1-4 alkoxyl group, R.sup.4 is (i) hydrogen atom or (ii) a C.sub.1-4 alkyl group. R.sup.5 is (i) a not-substituted C.sub.1-5 alkyl group or a C.sub.1-5 alkyl group substituted by a halogen atom, (ii) phenyl group or (iii) thienyl group and Z is (i) a C.sub.1-6 alkylene group, (ii) a C.sub.2-6 alkenylene group or (iii) a C.sub.3-6 alkynylene group or a pharmacologically acceptable salt thereof. According to the present invention, an anti-allergic agent and a therapeutic agent for ischemic heart disease without toxicity can be provided.
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: March 2, 1993
    Assignee: Kaken Pharmaceutical Co. Ltd.
    Inventors: Satoshi Murai, Masanao Shimano, Hiroshi Yamamoto, Toshihiro Koyama, Tsutomu Nakamura, Masaru Ogawa, Mitsuru Watanuki, Taira Okamoto, Toshimitsu Hori