Patents by Inventor Modassir Choudhry

Modassir Choudhry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS
    Publication number: 20240101976
    Abstract: This disclosure provides genetically engineered organisms with genetic modifications that are useful for producing desirable alkaloids. This disclosure also provides methods of making genetically engineered organisms that can produce desirable alkaloids. The organisms described herein produce alkaloids in amounts beyond that produced from comparable wild-type organisms. In certain embodiments, the genetically engineered organisms are fungi from the Basidiomycota division.
    Type: Application
    Filed: September 26, 2023
    Publication date: March 28, 2024
    Inventors: Thomas HENLEY, Modassir CHOUDHRY, Jose FERNANDEZ-GOMEZ, Antoine LARRIEU, Beata ORMAN-LIGEZA, Umar MOHAMMED, Emma MCKECHNIE-WELSH
  • Intracellular genomic transplant and methods of therapy
    Patent number: 11925664
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: March 12, 2024
    Assignees: INTIMA BIOSCIENCE, INC., REGENTS OF THE UNIVERSITY OF MINNESOTA, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Branden Moriarity, Beau Webber, David Largaespada, Modassir Choudhry, Steven A. Rosenberg
  • Genetic engineering of fungi to modulate tryptamine expression
    Patent number: 11905535
    Abstract: Provided herein are methods for modulating the psilocybin biosynthesis pathway in fungi or other organisms. Also provided are genetically modified fungi and organisms with induced and/or increased expression of psilocybin and psilocin and psilocybin and/or psilocin compositions generated by the provided methods.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: February 20, 2024
    Assignee: Empyrean Nueroscience, Inc.
    Inventors: Thomas Henley, Modassir Choudhry, Jose Fernandez-Gomez
  • Intracellular genomic transplant and methods of therapy
    Patent number: 11903966
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: February 20, 2024
    Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA, INTIMA BIOSCIENCE, INC., The U.S.A., as represented by the Secretary, Department f Health and Human Services
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • CELLULAR VACCINE PLATFORM AND METHODS OF USE
    Publication number: 20230293692
    Abstract: Cellular vaccine platforms, such as vaccine immune viral opsonization platforms, for eliciting host immune responses are disclosed. Also disclosed are the methods of making and using the cellular vaccine platforms in stimulating host immune responses.
    Type: Application
    Filed: October 20, 2022
    Publication date: September 21, 2023
    Inventors: Thomas HENLEY, Modassir CHOUDHRY
  • COMPOSITIONS AND METHODS OF GENERATING AN IMMUNE RESPONSE
    Publication number: 20230227778
    Abstract: Provided herein are compositions and methods for use in generating an immune response against a target peptide antigen. Also included, are methods for stabilizing, treating, and eliminating various diseases and conditions associated with target peptide expression.
    Type: Application
    Filed: October 20, 2022
    Publication date: July 20, 2023
    Inventors: Thomas HENLEY, Modassir CHOUDHRY
  • Intracellular genomic transplant and methods of therapy
    Patent number: 11642375
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: May 9, 2023
    Assignees: INTIMA BIOSCIENCE, INC., REGENTS OF THE UNIVERSITY OF MINNESOTA, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • Intracellular genomic transplant and methods of therapy
    Patent number: 11642374
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: May 9, 2023
    Assignees: INTIMA BIOSCIENCE, INC., REGENTS OF THE UNIVERSITY OF MINNESOTA, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • Modified cells and methods of therapy
    Patent number: 11583556
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: February 21, 2023
    Assignees: Regents of the University of Minnesota, Intima Bioscience, Inc., The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, R. Scott McIvor, David Largaespada, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
    Publication number: 20230015722
    Abstract: Genetically modified compositions, such as adeno-associated viral vectors and primary cells, for treating various conditions and diseases. Disclosed are also modified adeno-associated viruses for the treatment of cancer. Also disclosed are the methods of making and using the genetically modified compositions in treating various diseases, conditions, and cancer.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 19, 2023
    Inventors: Thomas HENLEY, Mavis AGBANDJE-MCKENNA, Tilmann BUERCKSTUEMMER, Lydia VINEY, Modassir CHOUDHRY
  • ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
    Publication number: 20230018860
    Abstract: Genetically modified compositions, such as adeno-associated viral vectors and primary cells, for treating various conditions and diseases. Disclosed are also modified adeno-associated viruses for the treatment of cancer. Also disclosed are the methods of making and using the genetically modified compositions in treating various diseases, conditions, and cancer.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 19, 2023
    Inventors: Thomas HENLEY, Mavis AGBANDJE-MCKENNA, Tilmann BUERCKSTUEMMER, Lydia VINEY, Modassir CHOUDHRY
  • GENETIC ENGINEERING OF FUNGI TO MODULATE TRYPTAMINE EXPRESSION
    Publication number: 20220396780
    Abstract: Provided herein are methods for modulating the psilocybin biosynthesis pathway in fungi or other organisms. Also provided are genetically modified fungi and organisms with induced and/or increased expression of psilocybin and psilocin and psilocybin and/or psilocin compositions generated by the provided methods.
    Type: Application
    Filed: July 15, 2022
    Publication date: December 15, 2022
    Inventors: Thomas HENLEY, Modassir CHOUDHRY, Jose FERNANDEZ-GOMEZ
  • GENETICALLY MODIFIED PLANTS AND METHODS OF MAKING THE SAME
    Publication number: 20220307043
    Abstract: Provided herein are methods for modulating the cannabinoid biosynthesis pathway in plants. Also provided are cannabinoid compositions comprising rare cannabinoids, new cannabinoids, and variant cannabinoids generated by the provided methods.
    Type: Application
    Filed: April 1, 2022
    Publication date: September 29, 2022
    Inventors: Thomas HENLEY, Modassir CHOUDHRY, Jose FERNANDEZ-GOMEZ
  • GENETIC ENGINEERING OF FUNGI TO MODULATE TRYPTAMINE EXPRESSION
    Publication number: 20220306997
    Abstract: Provided herein are methods for modulating the psilocybin biosynthesis pathway in fungi or other organisms. Also provided are genetically modified fungi and organisms with induced and/or increased expression of psilocybin and psilocin and psilocybin and/or psilocin compositions generated by the provided methods.
    Type: Application
    Filed: April 1, 2022
    Publication date: September 29, 2022
    Inventors: Thomas HENLEY, Modassir CHOUDHRY, Jose FERNANDEZ-GOMEZ
  • GENETICALLY MODIFIED PLANTS AND METHODS OF MAKING THE SAME
    Publication number: 20220298523
    Abstract: Provided herein are compositions comprising genetically modified cells, organisms, or plants described herein or extracts and products thereof and methods for making and using the same. Also provided are therapeutics derived from genetically modified cells, organisms, or plants described herein or extracts and products thereof for use in preventing, treating, or stabilizing disease and conditions.
    Type: Application
    Filed: April 1, 2022
    Publication date: September 22, 2022
    Inventors: Thomas HENLEY, Modassir CHOUDHRY, Jose FERNANDEZ-GOMEZ
  • MODIFIED CELLS AND METHODS OF THERAPY
    Publication number: 20220125843
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Application
    Filed: September 17, 2021
    Publication date: April 28, 2022
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, R. Scott McIvor, David Largaespada, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • TUMOR INFILTRATING LYMPHOCYTES AND METHODS OF THERAPY
    Publication number: 20220105133
    Abstract: Genetically modified compositions, such as non-viral vectors and tumor infiltrating lymphocytes, for the treatment of gastrointestinal cancer are disclosed. Disclosed are methods of utilizing a CRISPR system to generate genetically modified compositions. Also disclosed are the methods of making and using the genetically modified compositions for the treatment of gastrointestinal cancer.
    Type: Application
    Filed: September 22, 2021
    Publication date: April 7, 2022
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • MESOPHILIC ARGONAUTE SYSTEMS AND USES THEREOF
    Publication number: 20220089659
    Abstract: Constructs comprising Argonautes and neighboring genes are disclosed for use in gene editing. Disclosed are also compositions and methods utilizing these Argonautes and neighboring genes. Also disclosed are the methods of making and using the Argonautes and neighboring genes in treating various diseases, conditions, and cancer.
    Type: Application
    Filed: September 1, 2021
    Publication date: March 24, 2022
    Applicants: The Board of Trustees of the Leland Stanford Junior University, Intima Bioscience, Inc.
    Inventors: Lei S. Qi, Modassir Choudhry, Xueqiu Lin, Trevor N. Collingwood, Thomas Henley, Benjamin Klapholz, Tilmann Buerckstuemmer, Sejla Salic
  • Intracellular genomic transplant and methods of therapy
    Patent number: 11266692
    Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: March 8, 2022
    Assignees: Regents of the University of Minnesota, Intima Bioscience, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Branden Moriarity, Beau Webber, Modassir Choudhry, Steven A. Rosenberg, Douglas C. Palmer, Nicholas P. Restifo
  • MODIFIED ADENO-ASSOCIATED VIRAL VECTORS FOR USE IN GENETIC ENGINEERING
    Publication number: 20220064668
    Abstract: Adeno-associated virus has numerous advantages for its use in gene therapy. The present disclosures provide genetically modified adeno-associated viral vectors, and the methods of making the genetically modified adeno-associated viral vectors and compositions in treating cancer, other conditions, diseases, and disorders.
    Type: Application
    Filed: July 1, 2021
    Publication date: March 3, 2022
    Inventors: Modassir CHOUDHRY, Mavis AGBANDJE-MCKENNA, Tilmann BUERCKSTUEMMER, Thomas HENLEY, Lydia VINEY