Patents by Inventor Mohamad SABBAH

Mohamad SABBAH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230391725
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, R4, R4a, R4b, R4c, R4d, R4e, R4f, R5, R6 have the meaning as indicated in the description and claims The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating or preventing of one or more diseases or disorders associated with integrated stress response.
    Type: Application
    Filed: October 21, 2021
    Publication date: December 7, 2023
    Applicant: Evotec International GmbH
    Inventors: Holly Victoria Atton, Christopher John Brown, James Lindsay Carr, Gert-Jan Hofman, Mohamad Sabbah, Daryl Simon Walter
  • MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230391763
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R3, R4a, R4b, R4c, R4d, R4f, X1, X2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating or preventing of one or more diseases or disorders associated with integrated stress response.
    Type: Application
    Filed: October 21, 2021
    Publication date: December 7, 2023
    Applicant: Evotec International GmbH
    Inventors: Holly Victoria ATTON, Christopher John Brown, Serge Convers-Reignier, Christopher Francis Palmer, Mohamad Sabbah, Daryl Simon Walter
  • MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230382905
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, R4, R4a, R4b, R4c, R4d, R4e, R5, R6 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating or preventing of one or more diseases or disorders associated with integrated stress response.
    Type: Application
    Filed: October 21, 2021
    Publication date: November 30, 2023
    Applicant: Evotec International GmbH
    Inventors: Holly Victoria ATTON, Mohamad Sabbah
  • MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20230125481
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra1, Ra2, Ra4, Ra5, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.
    Type: Application
    Filed: January 26, 2021
    Publication date: April 27, 2023
    Inventors: Christopher John BROWN, James Lindsay CARR, Mohamad SABBAH, Jeffrey Michael SCHKERYANTZ, Daryl Simon WALTER
  • MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20220227747
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra2, Ra4, Ra5, Ra6, Ra7, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.
    Type: Application
    Filed: April 22, 2020
    Publication date: July 21, 2022
    Inventors: Holly ATTON, Christopher John BROWN, James Lindsay CARR, Serge CONVERS-REIGNIER, Michael CORR, Marissa FLOWER, Christopher Francis PALMER, Irena REBOULE, Mohamad SABBAH, Scott SADLER, Jonathan SHINE, Daryl Simon WALTER
  • MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY
    Publication number: 20220213078
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1 to R3, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing one or more diseases or disorders associated with integrated stress response.
    Type: Application
    Filed: April 22, 2020
    Publication date: July 7, 2022
    Inventors: Christopher John BROWN, Irena Doly REBOULE, York RUDHARD, Mohamad SABBAH, Daryl Simon WALTER