Abstract: A composition for improved oral care includes fibrillated material and friction elements for removal of plaque biofilm, and additional ingredients useful in oral care compositions. The composition also may include particulate SuperAbsorbent Polymer, which may be surface cross-linked. Certain ingredients may be minimized or avoided to reduce the lubricity of the composition. The composition may be a viscoelastic fluid having a desired viscosity, yield stress and elastic modulus. The efficacy can be characterized by its removal of biofilm due to flow inside tubes. Also useful are standard rheological and tribological measurements. Also disclosed are apparatus for administering the composition, and methods.

Abstract: In an embodiment, there is provided a catheter extender-lengthener comprising end connectors and tubing that comprises a polymer and a substance such as an antibiotic that is safe for exposure to bodily fluids. The catheter extender-lengthener is suitable to connect to a catheter extension set. Antibiotic can be eluted to fluid on both sides of a clamp and can diffuse toward the patient's body. Similar tubing can be used in a catheter extension set and optionally in a cap. The catheter extender-lengthener can be added on to existing catheter assemblies. Drugs can be combined at high concentration with polymer, and the device can elute effective amounts of minocycline and rifampin for more than a month. Use of the devices can provide adjustable antibiotic or dose and can be adjusted in response to a patient's condition. This can lessen the possibility of Catheter Related Blood Stream Infection.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: A drug-releasing polymer composition is disclosed. It may include a major component, which may be ethylene vinyl acetate, and may further include at least one or two release-modifying materials, and may further include at least one or two drugs. The release-modifying materials may be polyethylene glycol and polycaprolactone. The drugs may be minocycline and rifampin. There may be an interaction such that in the presence of two different release-modifying materials, drug release may be greater than with either release-modifying material alone. There may be an interaction such that in the presence of two drugs, drug release may be greater than with either drug alone, and antibacterial performance may be enhanced. Release durations as long as two months are possible. In addition, the composition can be provided on a medical device that is configured for implanting in body tissue for an extended time period.

Abstract: Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: An oral hygiene composition includes a mixture of: (i) a carrier liquid; and (ii) a water-insoluble hydratable polymer fibers forming an entangled three-dimensional network of said water-insoluble hydratable polymer fibers in said carrier; wherein: said carrier liquid comprises one or more humectant in a concentration of total humectant in excess of 5 wt. % based on the weight of the composition; said composition has an elastic modulus G? and a loss modulus G?, and said elastic modulus G? is larger that said loss modulus G?; and said water-insoluble hydratable polymer fibers have a diameter of about 10 to about 20,000 nm and a length of at least 100 nm.

Abstract: Methods of preventing and treating an ear infection comprising insertion of a tympanostomy tube comprised of a least one anti-biotic agent

Abstract: Methods of preventing and treating an ear infection comprising insertion of a tympanostomy tube comprised of a least one anti-biotic agent.

Abstract: A composition for improved oral care includes fibrillated material and friction elements for removal of plaque biofilm, and additional ingredients useful in oral care compositions. The composition also may include particulate SuperAbsorbent Polymer, which may be surface cross-linked. Certain ingredients may be minimized or avoided to reduce the lubricity of the composition. The composition may be a viscoelastic fluid having a desired viscosity, yield stress and elastic modulus. The efficacy can be characterized by its removal of biofilm due to flow inside tubes. Also useful are standard rheological and tribological measurements. Also disclosed are apparatus for administering the composition, and methods.

Abstract: Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Abstract: A method and a composition of cleaning and reprocessing a hemodialysis filtration membrane assembly that employs polyvinylpyrrolidone-containing membranes, the method comprising the step of treating the assembly with an aqueous mixture or a gas-liquid mixture comprising an inorganic base and from 100 to 1,000 ppm of a hypochlorite salt, wherein the mixture has a pH between about 12.0 and about 12.5, an oxidation reduction potential of less than 0.5 volts, a temperature of 40° to 55° C. and wherein the mole % of hypochlorous acid, HOCl, relative to the sum of hypochlorous acid plus hypochlorite anion, —OCl, is less than 0.004%.

Abstract: A method for cleaning an internal surface of a narrow diameter channel includes steps of: flowing a liquid cleaning medium and a gas through the narrow diameter channel under a flow regime that creates surface flow entities in contact with and sliding along the internal surface of the narrow diameter channel, the surface flow entities having three-phase contact lines and associated menisci, the surface flow entities detaching contaminants with which they come in contact from the internal surface of the narrow diameter internal surface of the narrow diameter channel; and rinsing the internal surface of the narrow diameter channel to remove residual liquid cleaning medium and detached contaminants from the channel.

Abstract: Methods of preventing and treating an ear infection comprising insertion of a tympanostomy tube comprised of a least one anti-biotic agent.