Abstract: Aspects herein are directed to a knit structure used to form a knit article where the knit structure can be adjusted to provide zoned cushioning, zoned insulation, zoned fit, zoned permeability/breathability features, and/or zoned tactile feedback features. The knit structure has a repeating pattern of a first number of knit courses having a first yarn knit with a first basic knit stitch and a second number of knit courses, where within each knit course of the second number of knit courses, the first yarn is knit in a repeating pattern having a first number of knit stitches knit with a second basic knit stitch and a second number of float stitches knit with a float stitch to form float areas.

Abstract: The present invention relates to cobicistat and its derivatives or prodrugs for use in the prophylaxis and/or treatment of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection, severe acute respiratory syndrome coronavirus (SARS-CoV) infection and/or Middle East respiratory syndrome coronavirus (MERS-CoV) infection. The present invention further relates to methods of prevention and/or treatment of SARS-CoV-2 infection.

Abstract: Aspects herein are directed to a knit structure used to form a knit article where the knit structure can be adjusted to provide zoned cushioning, zoned insulation, zoned fit, zoned permeability/breathability features, and/or zoned tactile feedback features. The knit structure has a repeating pattern of a first number of knit courses having a first yarn knit with a first basic knit stitch and a second number of knit courses, where within each knit course of the second number of knit courses, the first yarn is knit in a repeating pattern having a first number of knit stitches knit with a second basic knit stitch and a second number of float stitches knit with a float stitch to form float areas.

Abstract: A device for controlling a network gateway comprises at least one network interface configured to communicate in at least one computer network. The device further comprises a processing module configured to at least partially execute at least a first software module and a second software module. The first software module is configured to provide a gateway functionality of the network gateway via the at least one network interface. A functionality of the second software module is different from the gateway functionality of the first software module. The second software module is encapsulated from the first software module.

Abstract: Methods and devices for liquid-liquid extraction using digital microfluidic arrays are provided. A polar droplet is transported to a separation region containing a substantially non-polar solvent, where non-polar impurities may be extracted from the polar droplet while maintaining a distinct phase separation. In a preferred embodiment, biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in a separation step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with high precision and recovery.

Abstract: Methods and devices for liquid-liquid extraction using digital microfluidic arrays are provided. A polar droplet is transported to a separation region containing a substantially non-polar solvent, where non-polar impurities may be extracted from the polar droplet while maintaining a distinct phase separation. In a preferred embodiment, biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in a separation step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with high precision and recovery.

Abstract: A method of extracting hormones from a biological sample using digital microfluidic arrays is provided. Biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in an extraction step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with excellent precision and recovery.

Abstract: Methods and devices for liquid-liquid extraction using digital microfluidic arrays are provided. A polar droplet is transported to a separation region containing a substantially non-polar solvent, where non-polar impurities may be extracted from the polar droplet while maintaining a distinct phase separation. In a preferred embodiment, biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in a separation step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with high precision and recovery.

Abstract: A method of extracting hormones from a biological sample using digital microfluidic arrays is provided. Biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in an extraction step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with excellent precision and recovery.

Abstract: A system, method and computer program product for performing blind change detection audio segmentation that combines hypothesized boundaries from several segmentation algorithms to achieve the final segmentation of the audio stream. Automatic segmentation of the audio streams according to the system and method of the invention may be used for many applications like speech recognition, speaker recognition, audio data mining, online audio indexing, and information retrieval systems, where the actual boundaries of the audio segments are required.

Abstract: An abrasive article comprising an abrasive fabric comprising a fabric having discrete areas of electro-deposited metal extending on or therethrough and having abrasive material embedded in the metal, a layer of adhesive, and a backing substrate, the abrasive fabric being bonded to the backing substrate by the layer of adhesive, characterized in that either (i) the surface of the abrasive fabric bonded to the backing has been roughened and/or (ii) the layer of adhesive comprises an epoxy-acrylate thermosetting adhesive.