Patents by Inventor Mohammad K. Salajegheh

Mohammad K. Salajegheh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detecting inclusion body myositis
    Patent number: 9778250
    Abstract: Methods, devices, kits and systems for diagnosing inclusion body myositis (IBM) are provided. Methods, devices, kits and systems involves detecting the presence and/or level of autoantibodies that are reactive against at least a ˜43 kilodalton (kDa) protein or ˜43 kDa protein band from a muscle lysate or a mammalian cell lysate, or autoantibodies that are reactive against a cytosolic 5?-nucleotidase 1A protein (NT5C1A), or a cytosolic 5?-nucleotidase 1B protein (NT5C1B), or a NT5C1B isoform thereof, or a peptide fragment thereof, an isolated peptide thereof or a fusion protein comprising an isolated peptide of NT5C1A or NT5C1B. Such autoantibodies are only found in IBM patients and not in patients with other myopathies.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: October 3, 2017
    Assignees: The Brigham and Women's Hospital, Inc., Children's Medical Center Corporation
    Inventors: Steven A. Greenberg, Mohammad K. Salajegheh
  • DETECTING INCLUSION BODY MYOSITIS
    Publication number: 20140370526
    Abstract: Methods, devices, kits and systems for diagnosing inclusion body myositis (IBM) are provided. Methods, devices, kits and systems involves detecting the presence and/or level of autoantibodies that are reactive against at least a ˜43 kilodalton (kDa) protein or ˜43 kDa protein band from a muscle lysate or a mammalian cell lysate, or autoantibodies that are reactive against a cytosolic 5?-nucleotidase 1A protein (NT5C1A), or a cytosolic 5?-nucleotidase 1B protein (NT5C1B), or a NT5C1B isoform thereof, or a peptide fragment thereof, an isolated peptide thereof or a fusion protein comprising an isolated peptide of NT5C1A or NT5C1B. Such autoantibodies are only found in IBM patients and not in patients with other myopathies.
    Type: Application
    Filed: May 10, 2012
    Publication date: December 18, 2014
    Applicants: CHILDREN'S MEDICAL CENTER CORPORATION, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Steven A. Greenberg, Mohammad K. Salajegheh