Patents by Inventor Mohammed El-Sherbeini

Mohammed El-Sherbeini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Murd protein and gene of Pseudomonas aeruginosa
    Patent number: 6890910
    Abstract: This invention provides isolated polynucleotides that encode the MurD protein of Pseudomonas aeruginosa. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the of expression of murD and inhibitors of the activity of MurD, are also provided.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: May 10, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Mohammed El-Sherbeini, Barbara Azzolina
  • Murd protein and gene of Streptococcus pyogenes
    Patent number: 6746858
    Abstract: This invention provides the murD gene of Streptococcus pyogenes. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the expression of murD and inhibitors of the activity of MurD, are also provided.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: June 8, 2004
    Assignee: Merck & Co. Inc.
    Inventors: Mohammed El-Sherbeini, Kenny Kin Wong
  • MurD protein and gene of Staphylococcus aureus
    Patent number: 6534284
    Abstract: This invention provides the murD gene of Staphylococcus aureas. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the expression of murD and inhibitors of the activity of MurD, are also provided.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: March 18, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Mohammed El-Sherbeini, Kenny Kin Wong, Wayne M. Geissler
  • DNA encoding GLS1
    Patent number: 5955337
    Abstract: The DNA encoding glucan synthesis gene 1 (GLS1) is cloned and used in an in vitro assay to screen for compounds that modulate 1,3 .beta.-D glucan synthase activity.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: September 21, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Mohammed El-Sherbeini, Joseph A. Clemas
  • DNA encoding 1,3 beta-D glucan synthase subunits
    Patent number: 5821353
    Abstract: DNA molecules encoding proteins involved in biosynthesis of 1,3-beta-D glucan are identified, cloned, expressed and used in in vitro assays to screen for antifungal compounds, including compounds that affect cell wall biosynthesis. The invention includes but is not limited to the purified DNA molecules, assays employing the DNA molecules, proteins encoded by the DNA molecules, cells expressing the DNA molecules and altered forms of the molecules.
    Type: Grant
    Filed: August 1, 1996
    Date of Patent: October 13, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Cameron M. Douglas, Gary L. Chrebet, Joseph Clemas, Mohammed El-Sherbeini, Forrest Foor, Jennifer Nielsen Kahn, Rosemarie Kelly, Jean A. Marrinan, Nancy R. Morin, Janet C. Onishi, Stephen Authur Parent, Naasa M. Ramadan, Elizabeth A. Register, Gan-Ju Shei