Abstract: The method for robotic localization is a color-based method for determining the coordinates of a mobile robot. The mobile robot is initially positioned in one colored block of a colored grid imprinted on a surface, which is divided into a plurality of colored blocks extending along rows in a first direction and columns in a second direction. A degree of contrast of a first color respectively varies in each colored block in the rows extending in the first direction, and a degree of contrast of the second color respectively varies in each colored block in the rows extending in the second direction. A color sensor measures the degrees of contrast of the first color and the second color, and a localization system translates the measured degrees of contrast of the first color and the second color into respective positional coordinates in the first and second directions.

Abstract: Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Abstract: Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Abstract: The invention relates to compositions, medicaments, methods for treating individuals with high plasma lipid levels, and methods for screening drug candidates useful in, for example, the treatment of hypercholesterolemia. Specifically, the invention relates to the discovery that MTP inhibition leads to increased accumulation in cellular free-cholesterol and is useful in the development of compositions, medicaments, methods of treatment and drug screening methods to treat high plasma lipid levels.

Abstract: A parts rack for holding automotive parts for shipping and storing parts in the course of assembling of automobiles including a three dimensional framework which is assembled from elongated members detachably connected together using steel connectors to allow shipping of the racks disassembled and to allow quicker deliveries and also readily allow reconfiguration, repairs, and salvage of components.

Abstract: A dunnage bar system 10 that includes an bar 12 with a generally rectangular cross section. In one embodiment, the bar has four external faces 14, 16, 18, 20 that are joined by arcuate corners 22. The four faces 14, 16, 18, 20 include an impact-absorbing face 14 that has two arms of a C-section 30, 32; a basal face 16 opposing the impact-absorbing face 14; and a pair of side faces 18, 20 that are oriented between the impact-absorbing and basal faces 14 and 16. Preferably, a pair of channels 36 extend at least partially along and within the bar 12. Each channel 36 has a pair of opposing internal major walls 40, 40? and opposing internal minor walls 44, 44?. In alternative embodiments, one or more spacer members 70, 70? are insertable into the channels 36 for torsional rigidity and added support. Each wall terminates in an internal corner having a radius. The invention also includes a process for making the disclosed composite bar system.

Abstract: The present invention provides a windshield frame utilizing composite technology. More particularly, the windshield frame preferably comprises a fiber reinforced plastic molded upper frame section bonded with a structural grade adhesive to a fiber reinforced plastic molded lower frame section. According to the invention, steel reinforcements and tapping plates are bonded on or molded into the frame sections to stabilize the structure and provide hardware attachment points. Continuous carbon fibers may also be molded in the frame sections in critical high stress areas. The strength of the bonding between the frame sections is enhanced by a tongue and groove geometry along the interface. In addition, dowel pins and bushings are used to mechanically tie the frame sections together near body side attachment points.