Abstract: A signature handling system is provided to form and handle stacks of signatures. The signature handling system includes a stacker which receives signatures and forms stacks of signatures. A plurality of containers have side-by-side cells to hold the stacks of signatures. A conveyor is provided to sequentially move the containers to the stacker. The stacker includes a loader which loads the signatures into cells of the containers. The loader may be extendable through open sides of cells of the containers to move stacks of signatures downwardly into the cells of the containers through open upper end portions of the cells. The containers may be provided with doors which are movable between an open condition and a closed condition. When the doors are in the closed condition, they at least partially block open sides of the cells to retain stacks of signatures in the cells.