Patents by Inventor Mohosin Layek

Mohosin Layek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE
    Publication number: 20230220036
    Abstract: Improved process for the preparation of Semaglutide having the structural formula (I). His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys (C18 di acid mono-t-butyl-?-Glu(AEEA-AEEA)-OtBu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH?? Formula-I The present invention relates to the following fragments which are useful in the preparation of Semaglutide.
    Type: Application
    Filed: April 30, 2021
    Publication date: July 13, 2023
    Inventors: Khalid Anwer MOHAMMED, Rehana BEGUM, Shavali SHAIK, Kalesha SHAIK, Sunil Kumar GANDAVADI, Mohammed Sharif SHAIK, Mohosin LAYEK, Mahender Rao SIRIPRAGADA, Pavan Kumar JUJJURI, Hema Sundara Rao TELAKALA
  • Process for the manufacture of Degarelix and its intermediates
    Patent number: 9260480
    Abstract: The present invention relates to a liquid (or solution)-phase manufacturing process for preparing the decapeptide Degareiix, its amino-protected precursor, and other useful intermediates. The invention further relates to polypeptides useful in the solution-phase manufacturing process and to the purification of Degareiix itself. The manufacturing process comprises the step of cleaving the ?-amino protecting group P? from a Degareiix precursor according to formula {P4)(P?)Ac-AA1-AA10-NH2 in an organic solvent comprising the precursor and a cleaving agent dissolved therein: wherein P4 is a hydroxyl-protecting group or hydrogen, preferably hydrogen.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: February 16, 2016
    Assignee: Ferring B.V.
    Inventors: Dipak Kalita, Mohosin Layek, Atmakuri Venkata Dhanunjaya Rao, Venkat Aravinda Potula, Vikas Gajare, Kesavan Balakumaran, Anders Nilsson, Guangcheng Jiang
  • PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES
    Publication number: 20130281662
    Abstract: The present invention relates to a liquid (or solution)-phase manufacturing process for preparing the decapeptide Degareiix, its amino-protected precursor, and other useful intermediates. The invention further relates to polypeptides useful in the solution-phase manufacturing process and to the purification of Degareiix itself. The manufacturing process comprises the step of cleaving the ?-amino protecting group P? from a Degareiix precursor according to formula {P4)(P?)Ac-AA1-AA10-NH2 in an organic solvent comprising the precursor and a cleaving agent dissolved therein: wherein P4 is a hydroxyl-protecting group or hydrogen, preferably hydrogen.
    Type: Application
    Filed: October 26, 2011
    Publication date: October 24, 2013
    Applicant: Ferring B.V.
    Inventors: Dipak Kalita, Mohosin Layek, Atmakuri Venkata Dhanunjaya Rao, Venkat Aravinda Potula, Vikas Gajare, Kesavan Balakumaran, Anders Nilsson, Guangcheng Jiang