Patents by Inventor Mohsen Amir Alipour

Mohsen Amir Alipour has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lysosomal degradation of lipids and proteins and method of use thereof
    Patent number: 11298402
    Abstract: Methods for modulating lysosome-mediated microautophagy of a lipid or protein substrate in a cell are provided herein. In certain embodiments, said methods may comprise increasing lysosome-mediated microautophagy by treating the cell with a microautophagy-enhancing agent which increases lysosomal association-dissociation events between lysosomes and the cellular lipid or protein substrate and/or increases lysosomal degradation capacity; or decreasing lysosome-mediated microautophagy by treating the cell with a microautophagy-reducing agent which reduces lysosomal association-dissociation events between lysosomes and the cellular lipid or protein substrate and/or decreases lysosomal degradation capacity; thereby modulating lysosome-mediated microautophagy of the lipid or protein substrate.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: April 12, 2022
    Assignee: University of Ottawa
    Inventors: Mohsen Amir Alipour, Zemin Yao
  • LYSOSOMAL DEGRADATION OF LIPIDS AND PROTEINS AND METHOD OF USE THEREOF
    Publication number: 20190125827
    Abstract: Methods for modulating lysosome-mediated microautophagy of a lipid or protein substrate in a cell are provided herein. In certain embodiments, said methods may comprise increasing lysosome-mediated microautophagy by treating the cell with a microautophagy-enhancing agent which increases lysosomal association-dissociation events between lysosomes and the cellular lipid or protein substrate and/or increases lysosomal degradation capacity; or decreasing lysosome-mediated microautophagy by treating the cell with a microautophagy-reducing agent which reduces lysosomal association-dissociation events between lysosomes and the cellular lipid or protein substrate and/or decreases lysosomal degradation capacity; thereby modulating lysosome-mediated microautophagy of the lipid or protein substrate.
    Type: Application
    Filed: July 8, 2016
    Publication date: May 2, 2019
    Applicant: University of Ottawa
    Inventors: Mohsen Amir Alipour, Zemin Yao