Patents by Inventor Momoka Matsunami

Momoka Matsunami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying ligands to sour-taste receptors comprising PKD1L3 and PKDPKD2L1
    Patent number: 8512965
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: August 20, 2013
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • CELL LINES COMPRISING SOUR-TASTE RECEPTORS
    Publication number: 20120322084
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Application
    Filed: August 21, 2012
    Publication date: December 20, 2012
    Applicant: DUKE UNIVERSITY
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • CELL LINES COMPRISING SOUR-TASTE RECEPTORS
    Publication number: 20110311986
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Application
    Filed: August 22, 2011
    Publication date: December 22, 2011
    Applicant: DUKE UNIVERSITY
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • Cell lines comprising sour-taste receptors
    Patent number: 8003384
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: August 23, 2011
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • Modulators that promote cell surface expression of odorant receptors
    Patent number: 7879565
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: February 1, 2011
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • Modulators of odorant receptors
    Patent number: 7838288
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: November 23, 2010
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • MODULATORS OF ODORANT RECEPTORS
    Publication number: 20100222561
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Application
    Filed: April 26, 2010
    Publication date: September 2, 2010
    Applicant: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • SOUR TASTE RECEPTOR COMPOSITIONS AND METHODS
    Publication number: 20100136602
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Application
    Filed: December 7, 2009
    Publication date: June 3, 2010
    Applicant: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • Modulators of odorant receptors
    Patent number: 7691592
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: April 6, 2010
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • Sour taste receptor compositions and methods
    Patent number: 7629134
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: December 8, 2009
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • Modulators of odorant receptors
    Patent number: 7625714
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: December 1, 2009
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • MODULATORS OF ODORANT RECEPTORS
    Publication number: 20090123997
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Application
    Filed: October 30, 2008
    Publication date: May 14, 2009
    Inventors: HIROAKI MATSUNAMI, MOMOKA MATSUNAMI, HARUMI SAITO, HANYI ZHUANG
  • MODULATORS OF ODORANT RECEPTORS
    Publication number: 20090124003
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Application
    Filed: October 30, 2008
    Publication date: May 14, 2009
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • MODULATORS THAT PROMOTE CELL SURFACE EXPRESSION OF ODORANT RECEPTORS
    Publication number: 20090092997
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Application
    Filed: September 9, 2008
    Publication date: April 9, 2009
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • Modulators that promote cell surface expression of odorant receptors
    Patent number: 7425445
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: September 16, 2008
    Assignee: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • Modulators of odorant receptors
    Publication number: 20080124742
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Application
    Filed: June 8, 2007
    Publication date: May 29, 2008
    Applicant: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang
  • Sour taste receptor compositions and methods
    Publication number: 20080081345
    Abstract: The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
    Type: Application
    Filed: July 10, 2007
    Publication date: April 3, 2008
    Applicant: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
  • Modulators of odorant receptors
    Publication number: 20060057640
    Abstract: The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
    Type: Application
    Filed: June 20, 2005
    Publication date: March 16, 2006
    Applicant: Duke University
    Inventors: Hiroaki Matsunami, Momoka Matsunami, Harumi Saito, Hanyi Zhuang