Patents by Inventor Monique Nicoll

Monique Nicoll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) WITH MOSUNETUZUMAB
    Publication number: 20230287133
    Abstract: Disclosed herein are compositions and methods for the treatment of systemic lupus erythematosus using anti-CD20/anti-CD3 bispecific antibodies, such as mosunetuzumab.
    Type: Application
    Filed: November 15, 2022
    Publication date: September 14, 2023
    Applicant: Genentech, Inc.
    Inventors: Susan Lee LIMB, Matthew Dominic CASCINO, Monique NICOLL, Jay Prakash GARG, Michael Zecong LIAO
  • TAOJIKs as modifiers of the beta-catenin pathway and methods of use
    Patent number: 8003315
    Abstract: Human TAOJIK genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of TAOJIK are provided.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: August 23, 2011
    Assignee: Exelixis, Inc.
    Inventors: Michael A. Costa, Steven Brian Gendreau, Emery G. Dora, III, Monique Nicoll, Lenore Urbani, Jeffrey S. Larson
  • KIFS as Modifiers of the RHO Pathway and Methods of Use
    Publication number: 20110111402
    Abstract: Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.
    Type: Application
    Filed: September 24, 2010
    Publication date: May 12, 2011
    Applicant: EXELIXIS INC.
    Inventors: Joanne ADAMKEWICZ, Craig D. AMUNDSEN, Lynn Margaret BJERKE, George Ross FRANCIS, Timothy S. HEUER, Kim LICKTEIG, Monique NICOLL
  • VIPR1S as Modifiers of the E2F/RB Pathway and Methods of Use
    Publication number: 20100112566
    Abstract: Human VIPR1 genes are identified as modulators of the E2F/RB pathway, and thus are therapeutic targets for disorders associated with defective E2F/RB function. Methods for identifying modulators of E2F/RB, comprising screening for agents that modulate the activity of VIPR1 are provided.
    Type: Application
    Filed: September 24, 2007
    Publication date: May 6, 2010
    Inventors: Kyle A. Edgar, Kimberly Carr Ferguson, Monique Nicoll, Christopher G. Winter
  • Kifs as Modifiers of the Rho Pathway and Methods of Use
    Publication number: 20090004180
    Abstract: Human KIF23 genes are identified as modulators of the RHO pathway, and thus are therapeutic targets for disorders associated with defective RHO function. Methods for identifying modulators of RHO, comprising screening for agents that modulate the activity of KIF23 are provided.
    Type: Application
    Filed: November 9, 2006
    Publication date: January 1, 2009
    Applicant: Exelixis Inc.
    Inventors: Joanne Adamkewicz, Craig D. Amundsen, Lynn Margaret Bjerke, George Ross Francis, Timothy S. Heuer, Kim Lickteig, Monique Nicoll
  • Mbms as Modifiers of Branching Morphogenesis and Methods of Use
    Publication number: 20080213247
    Abstract: Human MBM genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MBM are provided.
    Type: Application
    Filed: October 22, 2003
    Publication date: September 4, 2008
    Inventors: Gregory D. Plowman, Felix D. Karim, Candace Swimmer, Hinrich Alexander Habeck, Thomas I. Koblizek, Stefan Schulte-Merker, Ulrike Langheinrich, Gordon Mark Stott, Torsten Trowe, Andreas Michael Vogel, Joerg Heinrich Odenthal, Jochen Konrad Scheel, Torsten Tilmann Will, Yisheng Jin, Lynn Margaret Bjerke, Bing Hai, Joanne I. Adamkewicz, Kim Licketeig, R. Glenn R. Hammonds, Craig D. Amundsen, Haiguang Zhang, Monique Nicoll
  • Sppls as Modifiers of the P53 Pathway and Methods of Use
    Publication number: 20070286852
    Abstract: Human SPPL genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SPPL are provided.
    Type: Application
    Filed: June 18, 2004
    Publication date: December 13, 2007
    Applicant: Exelixis, Inc.
    Inventors: Marcia Belvin, Helen Francis-Lang, Lori Friedman, Gregory Plowman, Monique Nicoll, Timothy Heuer
  • Presenilin enhancers assays
    Patent number: 7125687
    Abstract: The invention provides methods and compositions relating to pen polypeptides having pen-specific structure and activity, related polynucleotides and modulators of pen function. The invention provides isolated pen hybridization probes and primers capable of specifically hybridizing with natural pen genes, pen-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis (e.g. genetic hybridization screens for pen transcripts), therapy (e.g. pen inhibitors to modulate APP processing) and in the biopharmaceutical industry (e.g. as immunogens, reagents for screening chemical libraries for lead pharmacological agents, etc.).
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: October 24, 2006
    Assignee: Exelixis, Inc.
    Inventors: Daniel Tim Curtis, George Ross Francis, Michael Christopher Ellis, David Andrew Ruddy, Sharmon Monique Nicoll, Garth Joseph McGrath
  • MBCATs as modifiers of the beta-catenin pathway and methods of use
    Publication number: 20030224406
    Abstract: Human MBCAT genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of MBCAT are provided.
    Type: Application
    Filed: February 28, 2003
    Publication date: December 4, 2003
    Inventors: Michael A. Costa, Steven Brian Gendreau, Emery G. Dora, Monique Nicoll, Timothy S. Heuer
  • LGALS as modifiers of the CHK pathway and methods of use
    Publication number: 20030165965
    Abstract: Human LGALS genes are identified as modulators of the CHK pathway, and thus are therapeutic targets for disorders associated with defective CHK function. Methods for identifying modulators of CHK, comprising screening for agents that modulate the activity of LGALS are provided.
    Type: Application
    Filed: February 28, 2003
    Publication date: September 4, 2003
    Inventors: Helen Francis-Lang, Monique Nicoll, Timothy S. Heuer
  • TAOJIKs as modifiers of the beta-catenin pathway and methods of use
    Publication number: 20030157531
    Abstract: Human TAOJIK genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of TAOJIK are provided.
    Type: Application
    Filed: December 12, 2002
    Publication date: August 21, 2003
    Inventors: Michael A. Costa, Steven Brian Gendreau, Emery G. Dora, Monique Nicoll, Lenore Urbani, Jeffrey S. Larson