Abstract: A method of injecting a stream of treatment fluid into an earth formation in the course of drilling a borehole into the earth formation, using an assembly having a drill string provided with at least one sealing means arranged to selectively isolate a selected part of the borehole from the remainder of the borehole, the drill string further being provided with a fluid passage for the stream of treatment fluid into the selected part of the borehole, the method involving: operating the drill string, and stopping the drilling operation when a zone for which treatment is desired is arranged adjacent to the part of the selected part of the borehole; isolating the selected part of the borehole using the sealing means so as to seal the drill string relative to the borehole wall; and, pumping the stream of treatment fluid via the fluid passage into the selected part of the borehole and from there into the treatment zone.