Patents by Inventor Moo Je Sung

Moo Je Sung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
    Publication number: 20140135312
    Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Applicants: Astex Therapeutics Ltd., Novartis AG
    Inventors: Gilbert BESONG, Christopher Thomas Brain, Clinton A. Brooks, Miles Stuart Congreve, Claudio Dagostin, Guo He, Ying Huo, Steven Howard, Yue Ll, Yipin Lu, Paul Mortenston, Troy Smith, Moo Je Sung, Steven Woodhead, Wojciech Wrona, Bharat Lagu
  • Pyrrolopyrimidine compounds and their uses
    Patent number: 8685980
    Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: April 1, 2014
    Assignees: Novartis AG, Astex Therapeutics, Ltd.
    Inventors: Gilbert Ebai Besong, Christopher Thomas Brain, Clinton Alan Brooks, Miles Stuart Congreve, Claudio Dagostin, Guo He, Ying Hou, Steven Howard, Yue Li, Yipin Lu, Paul Neil Mortenson, Troy D. Smith, Moo Je Sung, Steven John Woodhead, Wojciech Wrona, Bharat Lagu
  • 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS
    Publication number: 20140051672
    Abstract: The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: August 7, 2013
    Publication date: February 20, 2014
    Inventors: Atwood Kim CHEUNG, Donovan Noel CHIN, Natalie DALES, Aleem FAZAL, Timothy Brian HURLEY, John KERRIGAN, Gary O'BRIEN, Lei SHU, Robert SUN, Moo Je SUNG
  • Pyrrolopyrimidine compounds and their uses
    Patent number: 8415355
    Abstract: The present invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and pharmaceutical compositions thereof. The present invention also relates to use of the compounds of formula (I) in modulating the activity of protein kinases and in the treatment of disease, particularly a disease, disorder or syndrome associated with CDK 4 inhibition.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: April 9, 2013
    Assignees: Novartis AG, Astex Therapeutics Ltd.
    Inventors: Christopher Thomas Brain, Moo Je Sung, Bharat Lagu
  • Pyrrolopyrimidine compounds and their uses
    Patent number: 8324225
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases, particularly pyrrolopyrimidine compounds and derivatives are described which inhibit protein kinases. The organic compounds are useful in treating proliferative disease.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: December 4, 2012
    Assignees: Novartis AG, Astex Therapeutics Limited
    Inventors: Christopher Thomas Brain, Moo Je Sung, Gebhard Thoma
  • PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
    Publication number: 20120207763
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases, particularly pyrrolopyrimidine compounds and derivatives are described which inhibit protein kinases. The organic compounds are useful in treating proliferative disease.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 16, 2012
    Applicants: ASTEX THERAPEUTICS LIMITED, NOVARTIS AG
    Inventors: Christopher Thomas BRAIN, Moo Je SUNG, Gebhard THOMA
  • Organic compounds
    Patent number: 8222248
    Abstract: The present invention provides compounds of the following structure; A-L1-B—C-D that are useful for treating or preventing conditions or disorders associated with DGAT1 activity in animals, particularly humans.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: July 17, 2012
    Assignee: Novartis AG
    Inventors: Moo Je Sung, Gary Mark Coppola, Taeyoung Yoon, Thomas A. Gilmore
  • ORGANIC COMPOUNDS
    Publication number: 20110046133
    Abstract: The present invention provides compounds of the following structure; A-L1-B-C-D that are useful for treating or preventing conditions or disorders associated with DGAT1 activity in animals, particularly humans.
    Type: Application
    Filed: October 17, 2007
    Publication date: February 24, 2011
    Inventors: Moo Je Sung, Gary Mark Coppola, Taeyoung Yoon, Thomas A. Gilmore
  • PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
    Publication number: 20100105653
    Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.
    Type: Application
    Filed: August 21, 2009
    Publication date: April 29, 2010
    Inventors: Gilbert Besong, Christopher Thomas Brain, Clinton A. Brooks, Miles Stuart Congreve, Claudio Dagostin, Guo He, Ying Huo, Steven Howard, Yue Li, Yipin Lu, Paul Mortenson, Troy Smith, Moo Je Sung, Steven Woodhead, Wojciech Wrona
  • Pyrrolopyrimidine Compounds and Their Uses
    Publication number: 20090318441
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases, particularly pyrrolopyrimidine compounds and derivatives are described which inhibit protein kinases. The organic compounds are useful in treating proliferative disease.
    Type: Application
    Filed: May 24, 2007
    Publication date: December 24, 2009
    Inventors: Christopher Thomas Brain, Moo Je Sung, Gebhard Thoma