Patents by Inventor Moon-Hi Han

Moon-Hi Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bio-Chip of Pattern-Arranged in Line, Method for Manufacturing the Same, and Method for Detecting an Analyte Bound in the Same
    Publication number: 20100159616
    Abstract: A bio-chip has a base plate, and a fluid resin layer positioned on the base plate and having a plurality of convexo-concave structures that are uniformly arranged in line. Side walls of the structures form reflecting films to form a Fabry-Perot interferometer structure. The bio-chip is used to detect an analyte provided to the bio-chip, so that it is possible to rapidly analyze the small amount of samples and to realize the detection sensitivity relatively higher than the conventional method.
    Type: Application
    Filed: April 16, 2007
    Publication date: June 24, 2010
    Applicant: KOREA TECHNOLOGY INDUSTRY CO., LTD.
    Inventors: Kwan Han Park, Kang Hoon Lee, Byong Chon Jon, Moon Hi Han, Yoon Suk Lee
  • High-throughput screening method for intergrin antagonist and new peptide screened therefrom
    Patent number: 7604982
    Abstract: The present invention relates to the screening method of antagonistic material of integrin using the protein chip and useful peptides screened thereby. The protein chip used in the present invention is unique substrate coated with new material, calixarene derivative, which can keep uniform and high activities of proteins. Integrin receptor protein is arrayed high densely on the chip, and materials (protein, peptide, small molecules and so on) specifically inhibiting the binding of ligand can be screened therewith. The integrins used in the present invention are integrin av f3 3 and integrin a1, b j3 3, and new antagonistic peptides screened from peptide library have high binding affinity.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: October 20, 2009
    Assignee: Proteogen Inc.
    Inventors: Moon-Hi Han, In-Cheol Kang, Yoon-Suk Lee, Soo-Ik Chang
  • High-Throughput Screening Method for Intergrin Antagonist and New Peptide Screened Therefrom
    Publication number: 20070249061
    Abstract: The present invention relates to the screening method of antagonistic material of integrin using the protein chip and useful peptides screened thereby. The protein chip used in the present invention is unique substrate coated with new material, calixarene derivative, which can keep uniform and high activities of proteins. Integrin receptor protein is arrayed high densely on the chip, and materials (protein, peptide, small molecules and so on) specifically inhibiting the binding of ligand can be screened therewith. The integrins used in the present invention are integrin av f3 3 and integrin a1, b j3 3, and new antagonistic peptides screened from peptide library have high binding affinity.
    Type: Application
    Filed: November 26, 2004
    Publication date: October 25, 2007
    Applicant: Proteogen, Inc.
    Inventors: Moon-Hi Han, In-Cheol Kang, Yoon-Suk Lee, Soo-Ik Chang
  • cDNAs encoding murine antibody against human plasma apolipoprotein B-100
    Patent number: 6096516
    Abstract: The present invention relates to cDNAs encoding murine antibodies against apolipoprotein B-100, the protein moiety of low density lipoprotein(LDL) in human plasma. In addition, the present invention relates to the method of preparation of recombinant antibodies specific for human plasma apolipoprotein B-100 of LDL, and use thereof, for diagnosis and treatment of cardiovascular diseases.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: August 1, 2000
    Assignee: Korea Institute of Science & Technology
    Inventors: Ju-Won Kwak, Moon-Hi Han, Byung-Kwon Choi
  • Vectors expressing ice nucleation protein fusions for cell surface anchoring of foreign proteins
    Patent number: 6071725
    Abstract: The present invention relates to surface anchoring vectors, a method for preparation of foreign proteins onto a cell surface and use thereof, which uses outer cell membrane protein, ice nucleation protein (NIP) derived from Pseudomonas syringae, a gram-negative bacterium.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: June 6, 2000
    Assignee: Korea Institute of Science and Technology
    Inventors: Jae Gu Pan, Heung Chae Jung, Seung Hwan Park, Moon Hi Han, Young Hoon Park
  • Method for controlling bleeding and microbial infections by administering thrombin, casein kinase II, and sphingosine
    Patent number: 5897860
    Abstract: The present invention relates to a hemostatic composition comprising at least 0.1 NIH U/ml of thrombin, about 0.01 mU/ml of casein kinase II, and from 10 ng/ml to 100 ng/ml of sphingosine or a sphingosine derivative. The composition is effective in treating patients suffering from hemophilia, ulcers, or microbial infections. In addition, the composition is effective in reducing clotting time during the surgical procedure of suturing blood vessels.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: April 27, 1999
    Assignee: Korea Institute of Science Technology
    Inventors: Seung-Ho Kim, Jin Young Lee, Moon Hi Han
  • CDNAS encoding murine antibody against human plasma apolipoprotein B-100
    Patent number: 5861276
    Abstract: The present invention relates to cDNAs encoding murine antibodies against apolipoprotein B-100. In addition, the present invention relates to methods of preparation of recombinant antibodies specific for human plasma apolipoprotein B-100 of LDL, and use thereof, for diagnosis and treatment of cardiovascular diseases.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: January 19, 1999
    Assignee: Korea Institute of Science & Technology
    Inventors: Ju-Won Kwak, Moon-Hi Han, Byung-Kwon Choi