Abstract: The present invention is directed to a method for treating and/or preventing skin, mucosal and systemic conditions resulting from microbial overgrowth, imbalance or infections comprising administering a composition to a mammalian subject, wherein said composition comprises oil obtained from Nigella sativa seeds, and wherein said oil comprises thymoquinone at a concentration of at least 2.5% w/w and one or more free fatty acids (FFAs) at a concentration of 2.5% w/w or less. The present invention is also directed to dosage forms comprising the aforementioned composition.

Abstract: The present invention is directed to composition comprising Nigella sativa (NS) oil, wherein said oil comprises thymoquinone (TQ) at a concentration of at least 2% (w/w). The composition is further characterized by having a much lower free fatty acid concentration than prior art compositions. The composition, which has anti-inflammatory activity, may be formulated for oral administration to a mammalian subject, for the purpose of preventing or treating inflammatory conditions and other disorders.

Abstract: The present invention provides a composition comprising a synergistic combination of thymoquinone and one or more omega-3 fatty acids, wherein the molar ratio between said thymoquinone and said one or more omega-3 fatty acids is at least 1:7. The present invention also provides a method of using said composition to treat or prevent inflammatory conditions.

Abstract: The present invention is directed to a process for the preparation of liquid or sludge slow-release compositions suitable for agricultural use, comprising one or more active ingredients selected from the group consisting of fertilizers, pesticides, lipophilic and/or hydrophilic compounds, and mixtures of non-pathogenic bacteria together with lipophilic and/or hydrophilic compounds, wherein these actives become encapsulated in an alginate matrix. The direction also encompasses compositions prepared by this process and methods for using said compositions for the delivery and slow release of agrochemicals and other actives in close proximity to the roots of plants.

Abstract: The present invention provides a composition comprising a synergistic combination of thymoquinone and one or more omega-3 fatty acids, wherein the molar ratio between said thymoquinone and said one or more omega-3 fatty acids is at least 1:7. The present invention also provides a method of using said composition to treat or prevent inflammatory conditions.

Abstract: The present invention is directed to a composition comprising a combination of thymoquinone (TQ) and one or more additional biologically active agents, wherein said biologically active agents are selected from the group consisting of carotenoids, Cannabis-related compounds and pycnogenol. In one preferred embodiment, the TQ is contained in cold-pressed Nigella sativa oil, wherein said oil is characterized by a TQ concentration of at least 1.5% (w/w) and a free fatty acid (FFA) content of 3.5% (w/w) or less. The present invention is also directed to methods for treating or preventing inflammatory conditions by means of administering these compositions.

Abstract: The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, Ginkgo biloba, and ?-phenylethylamine (PEA) or its salt. The invention is also directed to oral dosage forms containing said composition, and to a method of treatment of a psychological, psychiatric, behavioral and/or neurodevelopmental disorder comprising the administration of said compositions and dosage forms to a patient in need thereof.

Abstract: The invention provides a composition comprising oil obtained from Nigella sativa seeds and one or more surface-active agents. Preferably, the concentration of thymoquinone in the composition is at least 2% (w/w), wherein the concentration of the surface-active agent(s) is at least 0.2% (w/w), and wherein the one or more surface-active agents are selected from the group consisting of D-?-Tocopherol polyethylene glycol succinate (TPGS), lecithin and isolecithin. The invention also provides a method for preventing and/or treating pathological states and disorders associated with obesity, comprising the steps of administering a composition of the invention to a human subject.

Abstract: The present invention provides a method for supplying the nitrogen requirements of a plant comprising administering to said plant a combination of non-pathogenic, atmospheric nitrogen-fixing bacteria and one or more activating agents. Many of these activating agents possess potent anti-inflammatory and anti-microbial activity. The method is particularly suitable for use in enabling nitrogen fixation in plant species such as wheat, maize and other cereal crops, in which nitrogen fixation is normally not possible. The invention also provides compositions comprising nitrogen-fixing bacteria and suitable activating agents. In one preferred embodiment, the nitrogen fixing bacteria are of the Rhizobium genus.

Abstract: The present invention is directed to composition comprising Nigella sativa (NS) oil, wherein said oil comprises thymoquinone (TQ) at a concentration of at least 2% (w/w). The composition is further characterized by having a much lower free fatty acid concentration than prior art compositions. The composition, which has anti-inflammatory activity, may be formulated for oral administration to a mammalian subject, for the purpose of preventing or treating inflammatory conditions and other disorders.

Abstract: The present invention provides a composition comprising a synergistic combination of melatonin, valerenic acid and carnosic acid. The composition may be used in the treatment and prevention of several different disorders including inflammatory conditions, sleep disorders and anxiety. The invention also relates to several dosage forms which are suitable for the delivery of the claimed composition to subjects in need of treatment therewith.

Abstract: The present invention provides a composition comprising a synergistic combination of thymoquinone and one or more omega-3 fatty acids, wherein the molar ratio between said thymoquinone and said one or more omega-3 fatty acids is at least 1:7. The present invention also provides a method of using said composition to treat or prevent inflammatory conditions.

Abstract: The present invention is directed to a method for preventing and/or treating infection of plant or animal host species by fungal, bacterial and/or viral pathogens, wherein said method comprises the steps of providing a mixture of one or more non-pathogenic bacteria and one or more activating agents; and administering said mixture to said host species. The invention also encompasses compositions comprising a mixture of non-pathogenic bacteria and one or more activating agents.

Abstract: The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, ginkgo biloba, and ?-phenylethylamine (PEA) or its salt. The invention is also directed to oral dosage forms containing said composition, and to a method of treatment of a psychological, psychiatric, behavioral and/or neurodevelopmental disorder comprising the administration of said compositions and dosage forms to a patient in need thereof.

Abstract: The present invention provides a composition comprising a synergistic combination of melatonin, valerenic acid and carnosic acid. The composition may be used in the treatment and prevention of several different disorders including inflammatory conditions, sleep disorders and anxiety. The invention also relates to several dosage forms which are suitable for the delivery of the claimed composition to subjects in need of treatment therewith.

Abstract: The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, ginkgo biloba, and ?-phenylethylamine (PEA) or its salt. The invention is also directed to oral dosage forms containing said composition, and to a method of treatment of a psychological, psychiatric, behavioral and/or neurodevelopmental disorder comprising the administration of said compositions and dosage forms to a patient in need thereof.

Abstract: The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, ginkgo biloba, and ?-phenylethylamine (PEA) or its salt. The invention is also directed to oral dosage forms containing said composition, and to a method of treatment of a psychological, psychiatric, behavioral and/or neurodevelopmental disorder comprising the administration of said compositions and dosage forms to a patient in need thereof.