Patents by Inventor Moriya Blumkin

Moriya Blumkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mitochondrial augmentation therapy of muscle diseases
    Patent number: 11951135
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating muscle diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: April 9, 2024
    Assignee: Minovia Therapeutics Ltd.
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY
    Publication number: 20230338427
    Abstract: The present invention provides methods and compositions which cause the bone marrow to increase production of leukocyte cells. Specifically, the invention provides methods and compositions for increasing levels of CD45+ cells in a subject by providing mitochondrially-enriched cells. Further the present application provides methods for increasing bone marrow cellularity, engraftment of CD34+ cells and differentiation.
    Type: Application
    Filed: March 29, 2021
    Publication date: October 26, 2023
    Inventors: Natalie Yivgi-Ohana, Noa Sher, Moriya Blumkin
  • MITOCHONDRIA-ENRICHED GENETICALLY ENGINEERED CELLS AND USES THEREOF
    Publication number: 20230123731
    Abstract: The present invention is based on the discovery that cells enriched with mitochondria are useful for treating diseases and disorders. Disclosed are pharmaceutical compositions of mitochondrially-enriched genetically engineered T cells and methods of treatment using mitochondrially-enriched genetically engineered T cells.
    Type: Application
    Filed: March 30, 2021
    Publication date: April 20, 2023
    Inventors: Natalie Yivgi-Ohana, Noa Sher, Moriya Blumkin, Elad Jacoby
  • MITOCHONDRIAL AUGMENTATION THERAPY OF MUSCLE DISEASES
    Publication number: 20210290691
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating muscle diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 23, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY OF RENAL DISEASES
    Publication number: 20210275587
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating renal diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 9, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Moriya Blumkin, Noa Sher
  • MITOCHONDRIAL AUGMENTATION THERAPY OF OCULAR DISEASES
    Publication number: 20210275597
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating ocular diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 9, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY OF BRAIN DISEASES
    Publication number: 20210275599
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating brain diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: September 9, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY FOR PRIMARY MITOCHONDRIAL DISEASES
    Publication number: 20210260137
    Abstract: The present invention provides human stem cells enriched with functional mitochondria, wherein the healthy functional exogenous mitochondria constitute at least 3% and less than 33% of the total mitochondria in the mitochondrially-enriched human stem cells. Further disclosed are methods for the production of such cells, and uses thereof for the treatment of primary mitochondrial diseases.
    Type: Application
    Filed: July 22, 2019
    Publication date: August 26, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY OF LIVER DISEASES
    Publication number: 20210252075
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating liver diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: August 19, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY OF PANCREATIC DISEASES
    Publication number: 20210228642
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating pancreatic diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: July 22, 2019
    Publication date: July 29, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Noa Sher, Moriya Blumkin
  • MITOCHONDRIAL AUGMENTATION THERAPY OF RENAL DISEASES
    Publication number: 20210205368
    Abstract: The present invention provides stem cells enriched with healthy functional mitochondria, pharmaceutical compositions comprising these cells and methods of use thereof for treating renal diseases, disorders and symptoms thereof where the disease may or may not be associated with acquired mitochondrial dysfunction.
    Type: Application
    Filed: March 19, 2021
    Publication date: July 8, 2021
    Inventors: Natalie Yivgi Ohana, Uriel Halavee, Shmuel Bukshpan, Moriya Blumkin, Noa Sher