Patents by Inventor Morris F. White

Morris F. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IRS MODULATORS
    Publication number: 20200405817
    Abstract: This invention is directed to a general method for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating IRS2 activity in cells and tissues in the body. IRS1 and IRS2 are part of the insulin or insulin-like growth factor signaling pathway. By upregulating the levels or functional activity of IRS2, insuling is used more efficiently by the body to control nutrient levels. By upregulating IRS2 levels or functional activity in pancreatic ?-cells, glucose sensing and insulin secretion are enhanced.
    Type: Application
    Filed: May 18, 2020
    Publication date: December 31, 2020
    Inventors: Gerard M. Housey, Morris F. White
  • IRS MODULATORS
    Publication number: 20190046615
    Abstract: This invention is directed to a general method for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating IRS2 activity in cells and tissues in the body. IRS1 and IRS2 are part of the insulin or insulin-like growth factor signaling pathway. By upregulating the levels or functional activity of IRS2, insulin is used more efficiently by the body to control nutrient levels. By upregulating IRS2 levels or functional activity in pancreatic ?-cells, glucose sensing and insulin secretion are enhanced.
    Type: Application
    Filed: October 16, 2018
    Publication date: February 14, 2019
    Inventors: Gerard M. Housey, Morris F. White
  • METHODS OF UPREGULATING IRS FUNCTION
    Publication number: 20170035857
    Abstract: This invention is directed to a general method for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating IRS2 activity in cells and tissues in the body. IRS1 and IRS2 are part of the insulin or insulin-like growth factor signaling pathway. By upregulating the levels or functional activity of IRS2, insulin is used more efficiently by the body to control nutrient levels. By upregulating IRS2 levels or functional activity in pancreatic ?-cells, glucose sensing and insulin secretion are enhanced.
    Type: Application
    Filed: October 24, 2016
    Publication date: February 9, 2017
    Inventors: Gerard M. Housey, Morris F. White
  • IRS MODULATORS
    Publication number: 20140243398
    Abstract: This invention is directed to a general method for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating IRS2 activity in cells and tissues in the body. IRS1 and IRS2 are part of the insulin or insulin-like growth factor signaling pathway. By upregulating the levels or functional activity of IRS2, insulin is used more efficiently by the body to control nutrient levels. By upregulating IRS2 levels or functional activity in pancreatic ?-cells, glucose sensing and insulin secretion are enhanced.
    Type: Application
    Filed: September 27, 2013
    Publication date: August 28, 2014
    Applicant: HMI MEDICAL INNOVATIONS, LLC
    Inventors: Gerard M. Housey, Morris F. White
  • Method of screening activators and/or inhibitors of insulin receptor substrate 2
    Patent number: 8557512
    Abstract: This invention is directed to a general method for the chronic treatment, potential cure, or prevention of various metabolic and related diseases in people, including diabetes, by modulating IRS2 activity in cells and tissues in the body. IRS1 and IRS2 are part of the insulin or insulin-like growth factor signaling pathway. By upregulating the levels or functional activity of IRS2, insulin is used more efficiently by the body to control nutrient levels. By upregulating IRS2 levels or functional activity in pancreatic ?-cells, glucose sensing and insulin secretion are enhanced.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: October 15, 2013
    Assignee: HMI Medical Innovations, LLC
    Inventors: Gerard M. Housey, Morris F. White
  • DNA encoding an insulin receptor substrate
    Patent number: 5858701
    Abstract: A substantially pure nucleic acid comprising a sequence encoding an IRS-2 polypeptide, a substantially pure preparation of an IRS-2 polypeptide, and related methods.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: January 12, 1999
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Morris F. White, Xiao Jian Sun, Jacalyn H. Pierce
  • Concentric smoking filter having discrete tow and web filter media
    Patent number: 5746230
    Abstract: A concentric smoking filter in which one of the filter media is a fibrous tow, such as fibrous cellulose acetate tow, and one of the filter media is a web material, such as paper, is provided. The filter improves the taste, particularly, of "ultra-light" cigarettes.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 5, 1998
    Assignee: Philip Morris Incorporated
    Inventors: Cynthia W. Arterbery, W. Timothy Callaham, Gus D. Keritsis, Morris F. White, Jr.
  • Nucleic acid encoding pp60.sup.PIK and the methods of making pp60.sup.PIK
    Patent number: 5650293
    Abstract: A substantially pure nucleic acid comprising a sequence encoding a pp60.sup.PIK peptide and methods of using nucleic acid encoding pp60.sup.PIK to make pp60.sup.PIK polypeptide.
    Type: Grant
    Filed: June 10, 1994
    Date of Patent: July 22, 1997
    Assignee: Joslin Diabetes Center, Inc.
    Inventor: Morris F. White
  • Concentric smoking filter having cellulose acetate tow periphery and carbon-particle-loaded web filter core
    Patent number: 5622190
    Abstract: A concentric smoking filter in which the peripheral filter medium is a fibrous tow, such as fibrous cellulose acetate tow, and the core filter medium is a web material, such as paper, loaded with carbon particles, is provided. The filter improves the taste, particularly, of "ultra-light" cigarettes.
    Type: Grant
    Filed: November 15, 1994
    Date of Patent: April 22, 1997
    Assignee: Philip Morris Incorporated
    Inventors: Cynthia W. Arterbery, W. Timothy Callaham, Gus D. Keritsis, Donald E. Laslie, Kenneth A. Newman, Roger S. Slagle, Morris F. White, Jr.
  • Insulin receptor substrate
    Patent number: 5621075
    Abstract: A purified protein that is identified herein as insulin receptor substrate 1 (IRS-1) is disclosed, as well as a method of purifying IRS-1 and a recombinant nucleic acid encoding it.
    Type: Grant
    Filed: July 21, 1993
    Date of Patent: April 15, 1997
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: C. Ronald Kahn, Morris F. White, Paul L. Rothenberg
  • Concentric smoking filter having cellulose acetate tow periphery and carbon-particle-loaded web filter core
    Patent number: 5365951
    Abstract: A concentric smoking filter in which the peripheral filter medium is a fibrous tow, such as fibrous cellulose acetate tow, and the core filter medium is a web material, such as paper, loaded with carbon particles, is provided. The filter improves the taste, particularly, of "ultra-light" cigarettes.
    Type: Grant
    Filed: January 19, 1993
    Date of Patent: November 22, 1994
    Assignee: Philip Morris Incorporated
    Inventors: Cynthia W. Arterbery, W. Timothy Callaham, Gus D. Keritsis, Donald E. Laslie, Kenneth A. Newman, Roger S. Slagle, Morris F. White, Jr.
  • Isolated DNA encoding an insulin receptor substrate
    Patent number: 5260200
    Abstract: A purified nucleic acid consisting essentially of nucleic acid encoding insulin receptor substrate 1.
    Type: Grant
    Filed: October 15, 1992
    Date of Patent: November 9, 1993
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: C. Ronald Kahn, Morris F. White, Paul L. Rothenberg