Patents by Inventor Morten Thrane Nielsen

Morten Thrane Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF MACROCYCLIC DITERPENES IN RECOMBINANT HOSTS
    Publication number: 20180265897
    Abstract: The invention relates to recombinant microorganisms and methods for producing macrocyclic diterpene or oxidized macrocyclic diterpene.
    Type: Application
    Filed: December 30, 2015
    Publication date: September 20, 2018
    Inventors: Birger Lindberg Møller, Bjorn Hamberger, Roberta Callari, Dan Luo, Morten Thrane Nielsen
  • Methods for Producing Diterpenes
    Publication number: 20180037912
    Abstract: The present invention discloses that by combining different di TPS enzymes of class I and class II different diterpenes may be produced including diterpenes not identified in nature. Surprisingly it is revealed that a di TPS enzyme of class I of one species may be combined with a di TPS enzyme of class II from a different species, resulting in a high diversity of diterpenes, which can be produced.
    Type: Application
    Filed: January 30, 2015
    Publication date: February 8, 2018
    Inventors: Bjorn Hamberger, Birger Lindberg Moller, Johan Andersen-Ranberg, Carl Jorg Bohlmann, Philipp Zerbe, Morten Thrane Nielsen
  • STEREO-SPECIFIC SYNTHESIS OF (13R)-MANOYL OXIDE
    Publication number: 20160318893
    Abstract: The present invention relates to a method for manufacturing enantiomerically pure (13R)-manoyl oxide, said method comprising the steps of contacting geranylgeranyl diphosphate (GGPP) with a class II diterpene synthase to obtain labd-13-en-8,15-diol diphosphate (LPP), and then contacting the LPP with a class I diterpene synthase to obtain (13R)-manoyl oxide. The invention further relates to (13R)-manoyl oxide obtained by the method of the invention.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 3, 2016
    Inventors: Björn Hamberger, Eirini Pateraki, Birger Lindberg MØLLERø, Morten NØRHOLM, Morten Thrane Nielsen, Johan Andersen-Ranberg, Carl Jörg Bohlmann, Phillipp Zerbe
  • Biosynthetic engineering of glucosinolates
    Patent number: 9096863
    Abstract: The invention provides methods and materials, such as newly characterized genes, and novel processes, for converting a host from a phenotype whereby the host is unable to carry out glucosinolate (GSL) biosynthesis or chain elongation from an amino acid GSL-precursor to a phenotype whereby the host carries out said biosynthesis or elongation.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: August 4, 2015
    Assignee: University of Denmark
    Inventors: Fernando Geu Flores, Morten Thrane Nielsen, Michael Daigaard Mikkelsen, Barbara Ann Halkier, Morten Emil Møldrup
  • Biosynthetic Engineering of Glucosinolates
    Publication number: 20110016582
    Abstract: The invention provides methods and materials, such as newly characterised genes, and novel processes, for converting a host from a phenotype whereby the host is unable to carry out glucosinolate (GSL) biosynthesis or chain elongation from an amino acid GSL-precursor to a phenotype whereby the host carries out said biosynthesis or elongation.
    Type: Application
    Filed: February 27, 2009
    Publication date: January 20, 2011
    Applicant: University of Copenhagen
    Inventors: Fernando Geu-Flores, Morten Thrane Nielsen, Michael Daigaard Mikkelsen, Barbara Ann Halkier, Morten Emil Moldrup