Abstract: There is provided herein a flexible electronic circuit board for a tip section of a multi-camera endoscope, the circuit board comprising a front camera surface configured to carry a forward looking camera, a first side camera surface configured to carry a first side looking camera, a second side camera surface configured to carry a second side looking camera, one or more front illuminator surfaces a configured to carry one or more front illuminators to essentially illuminate the FOV of the forward looking camera, one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the first side looking camera and one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the second side looking camera.

Abstract: A mobile application development system includes a developer portal that receives an application from a developer and provides a routing library to the developer to augment the application. An offline analysis system analyzes the application to (i) determine a set of activities that a handler within the application is programmed to resume in response to respective resumption requests from a host operating system and (ii) determine parameters for each of the activities. The offline analysis system generates a set of links that each corresponds to a respective one of the activities. The routing library, installed as part of the augmented application onto a user device, receives a link, from the user device's operating system, that identifies a first activity. The routing library includes instructions for generating a first resumption request based on parameters corresponding to the first activity and transmitting the first resumption request to the augmented application's handler.

Abstract: There is provided herein a flexible electronic circuit board for a tip section of a multi-camera endoscope, the circuit board comprising a front camera surface configured to carry a forward looking camera, a first side camera surface configured to carry a first side looking camera, a second side camera surface configured to carry a second side looking camera, one or more front illuminator surfaces a configured to carry one or more front illuminators to essentially illuminate the FOV of the forward looking camera, one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the first side looking camera and one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the second side looking camera.

Abstract: Methods of inhibiting release of one or more cytokines, or inhibiting a cytokine storm, or preventing cytokine release syndrome or a cytokines storm, in a subject infected with severe acquired respiratory syndrome coronavirus 2. The method involves administering to the subject an effective amount of one or more NAD+ precursors, one or more inhibitors of stimulator of interferon genes (STING), one or more famesoid X receptor (FXR) agonists, or a combination thereof. In addition, treatment regimens involving the use of one or more NAD+ precursors, one or more STING inhibitors, one or more FXR agonists, or a combination thereof; and kits comprising pharmaceutical compositions of one or more NAD+ precursors, one or more inhibitors of stimulator of interferon genes, one or more farnesoid X receptor agonists, or combinations thereof.

Abstract: There is provided herein an optical system for a tip section of a multi-sensor endoscope, the system comprising: a front-pointing camera sensor; a front objective lens system; a side-pointing camera sensor; and a side objective lens system, wherein at least one of said front and side objective lens systems comprises a front and a rear sub-systems separated by a stop diaphragm, said front sub-system comprises, in order from the object side, a first front negative lens and a second front positive lens, said rear sub-system comprises, in order from the object side, a first rear positive lens, an achromatic sub-assembly comprising a second rear positive lens and a third rear negative lens, wherein the following condition is satisfied: f(first rear positive lens)?1.8f, where f is the composite focal length of the total lens system and f(first rear positive lens) is the focal length of said first rear positive lens.

Abstract: There is provided herein a flexible electronic circuit board for a tip section of a multi-camera endoscope, the circuit board comprising a front camera surface configured to carry a forward looking camera, a first side camera surface configured to carry a first side looking camera, a second side camera surface configured to carry a second side looking camera, one or more front illuminator surfaces a configured to carry one or more front illuminators to essentially illuminate the FOV of the forward looking camera, one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the first side looking camera and one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the second side looking camera.

Abstract: There is provided herein an optical system for a tip section of a multi-sensor endoscope, the system comprising: a front-pointing camera sensor; a front objective lens system; a side-pointing camera sensor; and a side objective lens system, wherein at least one of said front and side objective lens systems comprises a front and a rear sub-systems separated by a stop diaphragm, said front sub-system comprises, in order from the object side, a first front negative lens and a second front positive lens, said rear sub-system comprises, in order from the object side, a first rear positive lens, an achromatic sub-assembly comprising a second rear positive lens and a third rear negative lens, wherein the following condition is satisfied: f(first rear positive lens)?1.8f, where f is the composite focal length of the total lens system and f(first rear positive lens) is the focal length of said first rear positive lens.

Abstract: There is provided herein a flexible electronic circuit board for a tip section of a multi-camera endoscope, the circuit board comprising a front camera surface configured to carry a forward looking camera, a first side camera surface configured to carry a first side looking camera, a second side camera surface configured to carry a second side looking camera, one or more front illuminator surfaces a configured to carry one or more front illuminators to essentially illuminate the FOV of the forward looking camera, one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the first side looking camera and one or more side illuminator surfaces configured to carry one or more side illuminators to essentially illuminate the FOV of the second side looking camera.

Abstract: Aspects of the technology described herein relate to a method of treating a malignancy in a subject. This method involves selecting a subject having a malignancy and administering dimethyl-3-beta-hydroxy-cholenamide (DMHCA) or derivative thereof to the subject in an amount effective to treat the malignancy. Methods of reducing malignancy-associated fibrosis in a subject and pharmaceutical combinations comprising (i) DMHCA or derivative thereof and (ii) one or more immune checkpoint inhibitors are also disclosed.

Abstract: The subject matter discloses a medical imaging system and method for generating a video configuration from multiple cameras of a medical imaging endoscope. The system comprises a processing unit, operatively connected to the endoscope and to a monitor, the processing unit is instructed to receive multiple video data streams captured from the multiple cameras located at a distal tip of the endoscope; receive from the system a video mode defining a layout of the multiple video data streams; perform a video interpolation on the multiple video data streams according to the video mode; generate a video configuration for the multiple video data streams, the video configuration characters each video data stream of the multiple video data streams in different properties in accordance with the received video mode; send the video configuration to the monitor, and display the video configuration layout on the monitor.

Abstract: There is provided herein, an endoscope comprising an elongated shaft terminating with a tip section wherein said tip section comprises a permanent section connected to the elongated shaft and a removable section securely connectable to the permanent section, wherein the removable section comprises at least one capture device and at least one light source.

Abstract: There is provided herein a tip section of a multi-viewing element endoscope, the tip section comprising: two or more side-pointing viewing elements positioned at or in proximity to a distal end of said tip section, wherein each of said two or more side-pointing viewing elements having a discrete illuminator associated therewith, wherein the field of view provided by the two or more side-pointing viewing elements covers a front and side views; a working channel configured for insertion of a surgical tool; and a pathway fluid injector for inflating and/or cleaning a body cavity into which the endoscope is inserted.

Abstract: A system for maintaining a desired pressure difference between a first pressure within a chamber and a reference pressure at a reference space. The system may include a peristaltic pump located along a duct that connects the chamber with the reference space. The system may further include a pressure sensor for monitoring an actual pressure difference between the first pressure within the chamber and the reference pressure at the reference space. The system may also include a controller for receiving a signal from the pressure sensor for determining the actual pressure difference from the pressure sensor and for operating the peristaltic pump, in accordance with the actual pressure difference and the desired pressure difference, to increase, decrease or leave unchanged the pressure within the chamber so as to maintain the actual pressure difference within predetermined proximity to the desired pressure difference.

Abstract: There is provided herein, an endoscope comprising an elongated shaft terminating with a tip section wherein said tip section comprises a permanent section connected to the elongated shaft and a removable section securely connectable to the permanent section, wherein the removable section comprises at least one capture device and at least one light source.

Abstract: The subject matter disclosed in the present invention discloses a medical imaging device comprising at least two cameras. The medical imaging device comprises an elongated and narrow distal tip connected to a rigid elongated shaft member, wherein the distal tip can comprise a front camera and a first side camera. The cameras of the disclosed medical imaging device can be configured to provide variable cameras' magnifications, which in some cases may vary from one camera to another. The distal tip can comprise some optical gear required for the medical procedures. The optical gear located in the distal tip can comprise cameras, lenses and light sources required for the camera functioning. The cameras of the medical imaging device may be provided with dissimilarity in the cameras' magnification factors. Such dissimilarities are used to show the same object in the same size in a panoramic image captured simultaneously by multiple cameras, as the multiple cameras have multiple distances to the object.

Abstract: There is provided herein a tip section of a multi-viewing element endoscope, the tip section comprising: two or more side-pointing viewing elements positioned at or in proximity to a distal end of said tip section, wherein each of said two or more side-pointing viewing elements having a discrete illuminator associated therewith, wherein the field of view provided by the two or more side-pointing viewing elements covers a front and side views; a working channel configured for insertion of a surgical tool; and a pathway fluid injector for inflating and/or cleaning a body cavity into which the endoscope is inserted.

Abstract: A medical imaging device including at least two cameras. The medical imaging device includes an elongated and narrow distal tip connected to a rigid elongated shaft member, wherein the distal tip includes a front camera and a first side camera. The cameras of the disclosed medical imaging device can be configured to provide variable cameras' magnifications, which in some cases may vary from one camera to another. The cameras of the medical imaging device may be provided with dissimilarity in the cameras' magnification factors. Such dissimilarities are used to show the same object in the same size in a panoramic image captured simultaneously by the multiple cameras, as the multiple cameras have multiple distances to the object.

Abstract: A rotatable hanger device comprises: a mounting part comprising a front and back, the first side of the back fastenable to a first surface and the second side of the back positioned adjacent to the first side, and an arm positioned between the back and front, and connecting the back and front; and a housing part comprising a front and back, the first side of the back fastenable to a second surface and the second side of the back positioned adjacent to the first side, the front comprising a cut-out along an edge, and a wall connecting the housing back and front; wherein, the cut-out is sized and shaped relative to a size and shape of the arm, and wherein, the mounting and housing parts interlock such that the mounting front rests between the first side of the housing front and the second side of the housing back.

Abstract: A system and methods for solid freeform fabrication of an object is disclosed. The system comprises a solid freeform fabrication apparatus having a plurality of dispensing heads, a building material supply apparatus configured to supply a plurality of building materials to the fabrication apparatus, and a control unit configured for controlling the fabrication apparatus and the supply apparatus based on an operation mode selected from a plurality of predetermined operation modes.

Abstract: Apparatus for producing a three-dimensional model by sequentially forming layers of photopolymer material one on top of the other responsive to data defining the three-dimensional model is disclosed. The apparatus includes at least one printing head configured to dispense the photopolymer material, an array of LEDs controllable to provide radiation to polymerize the photopolymer material and a controller. The controller is configured to control the at least one printing head to dispense the photopolymer material to sequentially form the layers of material. The controller is also configured to turn on the array of LEDs to provide the radiation to cure the photopolymer material when situated above the model and to turn off the array of LEDs when not situated above the model.