Abstract: To provide a thermoplastic elastomer composition which is excellent in light resistance and flexibility and has high tear strength. [MEANS FOR SOLVING PROBLEMS] A thermoplastic elastomer composition comprising 100 parts by mass of acrylic multi-layer polymer particles (A) which each comprise at least two layers, i.e., at least one inner rubber layer (I) and at least one outermost thermoplastic resin layer (II), 5 to 300 parts by mass of an ethylene/vinyl ester copolymer (B), and 0.5 to 150 parts by mass of a graft copolymer (C) composed of an ethylene/vinyl ester copolymer backbone and a graft bonded to the backbone which consists of units derived from a monomer having a polarity higher than that of the backbone.

Abstract: An object of the present invention is to provide a cell culture chamber with which the survival rate of cells to be cultured can be increased, and a method of producing the same. A cell culture chamber according to the present invention includes a mass of projections formed of a plurality of microprojections 1 formed on a surface on which cells are cultured. The width or diameter of each of the microprojections 1 is in a range of 20 nm to 3 ?m, and the aspect ratio of each of the microprojections is in a range of 0.2 to 3.0. Thus, there can be provided a cell culture chamber most suitable for the adhesion and differentiation/proliferation of cells to be cultured.

Abstract: A microchannel array, a method of manufacturing the same, and a blood test method. The microchannel array is formed by joining first and second substrates, each including a fluid inlet and outlet on their surfaces. An internal space structure connects the fluid inlet and outlet, and includes an upstream flow channel connected with the fluid inlet, a downstream flow channel connected with the fluid outlet with a gap therebetween, and a micro flow channel connecting the upstream and downstream flow channels. A minimum distance from a center of a sectional surface of the micro flow channel to a side wall of the micro flow channel is smaller than that of the upstream and downstream flow channels. Each surface of the first and second substrates includes grooves for creating the upstream and downstream flow channels, and the surface of the second substrate has grooves for creating the micro flow channel.

Abstract: It is intended to provide a cell culture chamber in a shape suitable for cell culture. It is also intended to provide a cell culture chamber which is inexpensive and facilitates observation. A cell culture chamber (100) includes a cover (10), a chamber body (20) and a plate-shaped base (30). The cover (10) covers an opening (21) of the chamber body (20). The chamber body (20) contains a culture such as cells. The plate base (30) covers a through hole (24) formed at the bottom (23) of the chamber body (20). Moreover, the plate base (30) has fine pits and projections formed thereon for culturing the culture.

Abstract: To provide a cell culture chamber capable of reproducing a cell function in vivo, and a method of producing the same. The cell culture chamber according to the present invention has a concave-convex pattern formed on the surface on which cells are cultured. A concave portion of the concave-convex pattern includes cell culture portions and micro flow channels communicating with the cell culture portions. The bottom surface of each of the cell culture portions has a width 1.0 to 20 times an equivalent diameter of each of the cultured cells. A cell adhesion-inducing substance is formed only on the bottom surface and the side walls of the concave portion.

Abstract: [Problems]Relating to a bioassay method with the use of cultured cells and cell culture for a therapeutic purpose in the case of determining the efficacy of a drug or the like or examining the toxicity thereof, it is intended to provide a method of culturing cells under regulation in the extension direction and a cell culture plate. [Means for Solving Problems]A cell culture plate having a plural number of side walls (1) and a plural number of space structures (3) for providing cultured cells which are formed by the side walls (1), wherein the side walls (1) are provided with openings (2) so that the space structures (3) are linked together. By using this cell culture plate, a method of culturing cells under regulation in the extension direction can be provided.

Abstract: A microchannel array according to the present invention includes a first substrate 1, and a second substrate 11 bonded to the first substrate 1. Two sets, that is, a set of a first through-hole 9, a first recess 7, and a first groove 8 and a set of a second through-hole 4, a second recess 2, and a second groove 3 are formed on the first substrate 1. The different sets are separated by a partition 5. A cell differentation/proliferation speed after micro-injection can be increased by using such microchannel array.

Abstract: A thermoplastic polymer composition having good flexibility and excellent barrier properties with respect to gases and organic liquids, which can be adhesively bonded to a polyolefin resin, this composition comprising an ethylene-vinyl alcohol copolymer (A), a polymer mixture (B) composed of a block copolymer (I) mainly comprising a vinyl aromatic polymer block and a conjugated diene polymer block which may be hydrogenated, and a rubber softener (II), and a polyolefin resin (C), wherein at least part of the block copolymer (I) is modified at a modification ratio of 0.05 wt. % or higher so as to have a functional group capable of reacting with the ethylene-vinyl alcohol copolymer (A), wherein the ISO type A hardness of the thermoplastic polymer composition is not less than 30 and not higher than 90, and the oxygen permeation coefficient is 20,000 mL·20 ?m/m2·day·atm or less.

Abstract: An object of the present invention is to provide a process for producing microspheres that are solid microparticles or liquid microparticles for use as an emulsion employed in the food industry, production of medicine and cosmetic etc. or an emulsion for DDS (drug delivery system). The object is attained by a process for producing a microsphere including: separating a disperse phase from a continuous phase by a substrate 1 having a through-hole 7; and extruding the disperse phase into the continuous phase through the through-hole 7, in which the substrate having the through-hole 7 with a width of 0.5 to 500 ?m, a depth of 10 ?m to 6000 ?m and a ratio of the width to the depth of the through-hole 7 of 1 to 1/30 is a metal substrate.

Abstract: A microchannel array according to the present invention includes a first substrate 1, and a second substrate 11 bonded to the first substrate 1. Two sets, that is, a set of a first through-hole 9, a first recess 7, and a first groove 8 and a set of a second through-hole 4, a second recess 2, and a second groove 3 are formed on the first substrate 1. The different sets are separated by a partition 5. A cell differentation/proliferation speed after micro-injection can be increased by using such microchannel array.

Abstract: To provide a thermoplastic elastomer composition which is excellent in light resistance and flexibility and has high tear strength. [MEANS FOR SOLVING PROBLEMS] A thermoplastic elastomer composition comprising 100 parts by mass of acrylic multi-layer polymer particles (A) which each comprise at least two layers, i.e., at least one inner rubber layer (I) and at least one outermost thermoplastic resin layer (II), 5 to 300 parts by mass of an ethylene/vinyl ester copolymer (B), and 0.5 to 150 parts by mass of a graft copolymer (C) composed of an ethylene/vinyl ester copolymer backbone and a graft bonded to the backbone which consists of units derived from a monomer having a polarity higher than that of the backbone.

Abstract: A resin microchannel array includes a first substrate having a plurality of depressions, each depression having an inlet port at one end and an outlet port at another end, and walls sectioning the depressions, each wall having a micro groove connecting the depressions, and a second substrate having a flat surface bonded or pressure-contacted to a surface of the first substrate. Spaces created by the depressions and the grooves in a bonded or pressure contacted part between the first substrate and the second substrate serve as flow channels. Each of a width and a depth of the flow channel is within a range of 1 to 50 ?m, and a ratio of the width and the depth of the flow channel is within a range of 1:10 to 10:1.

Abstract: A cell culture plate has a plurality of flow channels, uneven pattern areas and through holes. The flow channels are formed between the uneven pattern areas, and culture solution flows from the flow channels into the uneven pattern areas or from the uneven pattern areas into the flow channels. The uneven pattern area has uneven patterns that create a cell culture space.

Abstract: A method for the production of a tubular article resulting from joining by insertion a tubular body possessed of a layer having of a thermoplastic resin composition containing a styrene type elastomer and a polyolefin type resin and a tubular body having of a thermoplastic resin composition containing a polyolefin, having the ratio of the outside diameter of a thin tube and the inner diameter of a thick tube (outside diameter of thin tube/inside diameter of thick tube=X) in the range of 1<X<1.25, interposing an absorbent having an absorption wavelength of 700-2,500 nm in the connected part of the tubular body and/or the tubular body, and irradiating the tubular bodies with a laser beam. By connecting tubular bodies using specific resin compositions and having specific inside diameter and outside diameter, the connected parts can be made to adhere strongly.

Abstract: A laminate comprising at least a surface layer (I) and an adjacent layer (II) thereto, characterized in that the surface layer (I) comprises a cross-linked copolymer formed by cross-linking a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound, and the adjacent layer (II) comprises a hydrogenated copolymer formed by hydrogenating a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound; a multilayer tube comprising the laminate; and a medical device comprising the laminate, and/or the multilayer tube.

Abstract: A multi-layered tube composed of at least two layers, each formed from a different resin, e.g. resin (I) or resin (II). Resin (I) contains 5 to 40 mass % of a polypropylene resin and 95 to 60 mass % of at least one hydrogenated copolymer. Resin (II) contains 45 to 100 mass % of a polypropylene resin and 55 to 0 mass % of a hydrogenated copolymer. The multi-layered tubes may be used in the field of medicine and provide tubing which is excellent in transparency, flexibility and anti-kinking properties, and which is durable during sterilization procedures with high-pressure steam. The multilayer tubing may also be safely disposed of as it generates no toxic gases, such as dioxin, when incinerated. The multilayered tubing has excellent connectability and may be bonded to other tubing using hot solvent bonding or solvent adhesion. The multilayered tubing which is free from generation of any toxic gas when incinerated, and which is excellent in hot solvent bonding or solvent adhesion to other tube.

Abstract: The resin microchannel substrate has a surface where a recess leading to a fluid supply port and a bank adjacent to the recess and having many micro grooves on a surface are formed. The grooves form microchannels connecting the inside of the recess and the outside of the recess when the surface of the substrate is firmly attached to a flat plate serving as a cover. The width and height of the microchannel are within a range of 1 to 300 ?m, and the width/height ratio of the channel is within a range of 1:20 to 20:1.

Abstract: A laminate comprising at least a surface layer (I) and an adjacent layer (II) thereto, characterized in that the surface layer (I) comprises a cross-linked copolymer formed by cross-linking a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound, and the adjacent layer (II) comprises a hydrogenated copolymer formed by hydrogenating a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound; a multilayer tube comprising the laminate; and a medical device comprising the laminate, and/or the multilayer tube.

Abstract: A thermoplastic polymer composition having good flexibility and excellent barrier properties with respect to gases and organic liquids, which can be adhesively bonded to a polyolefin resin, this composition comprising an ethylene-vinyl alcohol copolymer (A), a polymer mixture (B) composed of a block copolymer (I) mainly comprising a vinyl aromatic polymer block and a conjugated diene polymer block which may be hydrogenated, and a rubber softener (II), and a polyolefin resin (C).

Abstract: A resin molded product production process has a resist pattern formation step including formation of the first resist layer on s substrate, positioning of the substrate and a mask A, exposure of the first resist layer using the mask A, heat-treatment of the first resist layer, formation of the second resist layer on the first resist layer, positioning of the substrate and a mask B, exposure of the second resist layer using the mask B, heat-treatment of the second resist layer, and development of the resist layers, thereby creating a given resist pattern. The production process further has a metal structure formation step of depositing a metal on the substrate in accordance with the resist pattern by plating, and a molded product formation step of forming a resin molded product by using the metal structure as a mold. A resin molded product is thereby produced.