Patents by Inventor Motohiro Yamazaki
Motohiro Yamazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20210293711Abstract: There is a phenomenon where a noise in a spike shape caused by, for example, impurities and a noise peak having a spectrum different from a wavelength spectrum of a labeled fluorescent substance are detected during a capillary electrophoresis. Therefore, the disclosure provides a technique to identify an intensity of the labeled fluorescent substance itself without an effect by a noise fluorescence peak caused by impurities. In the disclosure, a fluorescence intensity property (a fluorescence profile of a noise) common to the noise peaks is set, the noise peak is handled as a fluorescent substance different from the labeled fluorescent substance, and the fluorescent substance and the noise are separated by color converting with the labeled fluorescent substance+the noise fluorescent substance (see FIG. 5).Type: ApplicationFiled: August 2, 2018Publication date: September 23, 2021Applicant: Hitachi High-Tech CorporationInventors: Satoshi Takahashi, Michiru Fujioka, Mikihiro Kobayashi, Isao Haraura, Takeshi Ooura, Motohiro Yamazaki
-
Patent number: 11125720Abstract: A capillary electrophoresis apparatus is disclosed that does not discharge and achieves both compactness and performance even with a part configuration having insufficient spatial distance or creeping distance. This capillary electrophoresis apparatus is provided with a resistance heater for heating capillaries, an electrode holder that holds capillary electrodes and is connected to a high-voltage unit, and a conductive member that at least partially comprises metal and has been grounded to a low potential. The electrode holder and conductive member are in contact with heat-dissipating rubber disposed there between that composes a structure comprising an insulation member. As a result of this configuration, discharge risk is reduced through the reduction of the potential of parts near the high-voltage unit and the slow reduction of the high potential of the high-voltage unit.Type: GrantFiled: March 18, 2016Date of Patent: September 21, 2021Assignee: Hitachi High-Tech CorporationInventors: Taro Nakazawa, Motohiro Yamazaki, Kenko Uchida, Akira Fujii
-
Patent number: 11061243Abstract: A dichroic-mirror array in which a plurality of dichroic mirrors are arranged, and by satisfying a predetermined relationship between a width, a thickness, a material, a tilt, an interval, and a step difference of dichroic mirrors, the dichroic-mirror array is miniaturized, an optical path length is reduced, and at the same time, an aperture width is increased.Type: GrantFiled: February 22, 2016Date of Patent: July 13, 2021Assignee: Hitachi High-Tech CorporationInventors: Takashi Anazawa, Motohiro Yamazaki
-
Publication number: 20210190725Abstract: In order to provide a piston and a syringe with good sliding performance and pressure resistance performance, the piston contained in the syringe that pressurizes or decompresses an internal medium is configured such that a soft portion made of a soft material and a rigid portion made of a material having rigidity higher than rigidity of the soft portion, are connected in series, and arranged such that the soft portion is in contact with the medium and the rigid portion is not in contact with the medium. The soft portion includes a hollow on a surface in contact with the medium. The rigid portion has an end surface facing the soft portion, the end surface including at least an outer peripheral portion in contact with the soft portion. The outer diameter of the soft portion is larger than the outer diameter of the rigid portion, and the outer diameter of the rigid portion is slightly smaller than the inner diameter of an outer cylinder of the syringe.Type: ApplicationFiled: October 9, 2018Publication date: June 24, 2021Inventors: Takashi ANAZAWA, Kunio HARADA, Motohiro YAMAZAKI
-
Publication number: 20210190689Abstract: The invention is directed to a light-emission detection apparatus for individually condensing light emitted from each emission point of a emission-point array using each condensing lens of a condensing-lens array to form a light beam and detecting each light beam incident on a sensor in parallel, and the light-emission detection apparatus can be downsized and high sensitivity and low crosstalk can be simultaneously accomplished when a certain relation between the diameter of each emission point, a focal length of each condensing lens, an interval of condensing lenses, and an optical path length between each condensing lens and a sensor is satisfied.Type: ApplicationFiled: February 22, 2016Publication date: June 24, 2021Inventors: Takashi ANAZAWA, Motohiro YAMAZAKI
-
Patent number: 11029281Abstract: This drive screw device is provided with: a drive screw; a drive unit which causes the drive screw to rotate; a slider which moves along the drive screw by means of the rotation of the drive screw; and an external load which is provided on the drive screw and applies a rotational load to the drive screw. By this means it is possible to provide a drive screw device with which there is little pressure variation even if a frictional force varies.Type: GrantFiled: September 23, 2016Date of Patent: June 8, 2021Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Katsuhiro Aritome, Ryusuke Kimura, Motohiro Yamazaki, Go Nakajima, Naomichi Kawasaki
-
Publication number: 20210164937Abstract: A capillary cartridge achieves both improvement of attachability and improvement of heat dissipation performance for realizing short-time analysis. A heat dissipation body is provided between a capillary having a detection unit provided in a part thereof and a plate-like support body that supports the capillary, and temperature increase inside the capillary is suppressed by the heat dissipation body, and thereby, electrophoresis can be performed under a high voltage application condition where the amount of heat increases and analysis time is reduced. In addition, it is possible to redress complexity of an operation by reducing a fixing place at the time of attachment to only a detection unit and an electrode holder by using an integration structure in which the capillary, the supporting body, and the heat radiating body are integrated.Type: ApplicationFiled: February 5, 2021Publication date: June 3, 2021Inventors: Ayaka OKUNO, Motohiro YAMAZAKI, Taro NAKAZAWA, Mitsuhiro MIYAZAKI, Ryusuke KIMURA
-
Publication number: 20210156821Abstract: An electrophoresis device has: a sample tray (112) on which there are placed a positive-electrode-side buffer solution container (103) containing a buffer solution and a phoresis medium container (102) containing a phoresis medium, and which is driven in a vertical direction and a horizontal direction; a thermostat oven unit (113) that holds a capillary array having a capillary head in which a plurality of capillaries are bundled in a single unit at one end thereof in a state where the capillary array being held in a state in which the capillary head protrudes downward, and that keeps the interior temperature constant; a solution-delivering mechanism (106) for delivering the phoresis medium in the phoresis medium container to the capillary array from the capillary head; and a power source for applying a voltage to both ends of the capillary array. Holes for insertion of the capillary head are provided in upper sections of the positive-electrode-side buffer solution container and the phoresis medium container.Type: ApplicationFiled: July 31, 2017Publication date: May 27, 2021Inventors: Katsuhiro ARITOME, Ryusuke KIMURA, Motohiro YAMAZAKI
-
Patent number: 10942121Abstract: In order to avoid crosstalk between images by a simple method, an optical system through which lights emitted from a plurality of light emission points pass, and a measurement unit that measures lights imaged by the optical system are provided, and a midpoint of two arbitrary light emission points among the light emission points is shifted away from a center of the optical system. More specifically, the center of the optical system exists outside a light emission point group consisting of the plurality of the light emission points. With the above configuration, main images and ghost images are separated each other, and thus, it is possible to avoid crosstalk caused by ghosting and to correctly analyze emissions from the plurality of the light emission points.Type: GrantFiled: August 29, 2018Date of Patent: March 9, 2021Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Takashi Anazawa, Motohiro Yamazaki, Taro Nakazawa, Michiru Fujioka
-
Patent number: 10942147Abstract: A capillary cartridge achieves both improvement of attachability and improvement of heat dissipation performance for realizing short-time analysis. A heat dissipation body is provided between a capillary having a detection unit provided in a part thereof and a plate-like support body that supports the capillary, and temperature increase inside the capillary is suppressed by the heat dissipation body, and thereby, electrophoresis can be performed under a high voltage application condition where the amount of heat increases and analysis time is reduced. In addition, it is possible to redress complexity of an operation by reducing a fixing place at the time of attachment to only a detection unit and an electrode holder by using an integration structure in which the capillary, the supporting body, and the heat radiating body are integrated.Type: GrantFiled: July 1, 2015Date of Patent: March 9, 2021Assignee: Hitachi High-Tech CorporationInventors: Ayaka Okuno, Motohiro Yamazaki, Taro Nakazawa, Mitsuhiro Miyazaki, Ryusuke Kimura
-
Patent number: 10884008Abstract: Provided are: a device for storing biochemical reagents wherein an amount of a reagent can be hermetically stored and dropped from a storage site without coming into contact with the outside air; and a biochemical analyzer using the device. The device (10) is constituted by: sticking a top sheet (32) to a base sheet (31) provided with a convex-shaped hollow pocket (16) in which a reagent can be housed; a reagent container as a PTP packaging sheet (30) wherein an opening of the pocket in the base sheet (31), in which a reagent is preliminarily housed, is hermetically sealed with the top sheet (32); and sticking the film sheet surface as the top sheet (32) of the PTP packaging sheet (30), in which the reagent is hermetically packaged, to a cartridge surface of a device body (20) to thereby hermetically seal the inside of the device body too.Type: GrantFiled: April 27, 2015Date of Patent: January 5, 2021Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Taro Nakazawa, Motohiro Yamazaki, Tatsuya Yamashita, Yoshitaka Kodama
-
Publication number: 20200398275Abstract: Provided is a specimen-processing device configured so that a flow operation can be performed by deforming an elastic membrane. The present invention has an analysis chip that is a processing unit having a first flow path through which a liquid flows on a lower-surface side, a drive unit that controls air, a membrane that is an elastic membrane disposed between the processing unit and the drive unit, and an air pressure control unit that switches the elastic membrane between adhering to the processing-unit side and adhering to the drive-unit side. The processing unit has formed therein a circulation groove that is a second flow path through which air flows, the circulation groove being formed on the opposite side from the side where the drive unit is disposed, and an adhesion film that is a hermetic sealing film, the adhesion film being provided above the second flow path of the processing unit.Type: ApplicationFiled: January 23, 2019Publication date: December 24, 2020Inventors: Yoshihiro NAGAOKA, Motohiro YAMAZAKI
-
Publication number: 20200292493Abstract: Provided is an electrophoresis device that, by electrophoresis, feeds a sample into capillaries and optically detects the sample, the electrophoresis device being provided with capillaries, a capillary head provided at the distal end of the capillaries, a phoretic medium-filled container used for electrophoresis and filled with a phoretic medium, a guide member that covers the side surface of the phoretic medium-filled container, a seal member that seals from below the phoretic medium filled in the phoretic medium-filled container, and a plunger that presses the seal member.Type: ApplicationFiled: May 28, 2020Publication date: September 17, 2020Inventors: Ryusuke KIMURA, Motohiro YAMAZAKI, Hitoshi MIYATA, Hiroyuki HIGASHINO
-
Publication number: 20200271584Abstract: In order to avoid crosstalk between images by a simple method, an optical system through which lights emitted from a plurality of light emission points pass, and a measurement unit that measures lights imaged by the optical system are provided, and a midpoint of two arbitrary light emission points among the light emission points is shifted away from a center of the optical system. More specifically, the center of the optical system exists outside a light emission point group consisting of the plurality of the light emission points. With the above configuration, main images and ghost images are separated each other, and thus, it is possible to avoid crosstalk caused by ghosting and to correctly analyze emissions from the plurality of the light emission points.Type: ApplicationFiled: August 29, 2018Publication date: August 27, 2020Applicant: Hitachi High-Tech CorporationInventors: Takashi ANAZAWA, Motohiro YAMAZAKI, Taro NAKAZAWA, Michiru FUJIOKA
-
Patent number: 10753873Abstract: A multicolor detection device includes: a condensing lens array 17 in which a plurality of condensing lenses 18, each of which turns light emitted from each of a plurality of light emitting points 1 individually into parallel light beams, are arranged, the light emitting points being arranged in a light emitting point array; at least one spectroscopic element on which the parallel light beams are incident in parallel, the at least one spectroscopic element being common; and at least one sensor on which light beams spectrally separated by the spectroscopic element are incident in parallel, the at least one sensor being common.Type: GrantFiled: November 30, 2018Date of Patent: August 25, 2020Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Takashi Anazawa, Satoshi Takahashi, Motohiro Yamazaki, Yoshitaka Kodama
-
Patent number: 10705046Abstract: Provided is an electrophoresis device that, by electrophoresis, feeds a sample into capillaries and optically detects the sample, the electrophoresis device being provided with capillaries, a capillary head provided at the distal end of the capillaries, a phoretic medium-filled container used for electrophoresis and filled with a phoretic medium, a guide member that covers the side surface of the phoretic medium-filled container, a seal member that seals from below the phoretic medium filled in the phoretic medium-filled container, and a plunger that presses the seal member.Type: GrantFiled: March 27, 2015Date of Patent: July 7, 2020Assignee: Hitachi High-Tech CorporationInventors: Ryusuke Kimura, Motohiro Yamazaki, Hitoshi Miyata, Hiroyuki Higashino
-
Publication number: 20200200705Abstract: The present invention addresses the problem of providing an electrophoretic medium container capable of stabilizing a liquid delivery pressure while ensuring sealing of an electrophoretic medium. In order to resolve this problem, this electrophoretic medium container is provided with a syringe part for holding an electrophoretic medium, and a sealing component for sealing one end of the syringe part, the electrophoretic medium container being characterized in that the sealing component has a sealing surface, a body part, and a groove provided between the sealing surface and the body part, wherein the sealing surface is in contact with the inner wall of the syringe part.Type: ApplicationFiled: June 28, 2017Publication date: June 25, 2020Inventors: Naomichi KAWASAKI, Ryusuke KIMURA, Katsuhiro ARITOME, Go NAKAJIMA, Takashi GOMI, Motohiro YAMAZAKI
-
Publication number: 20200057022Abstract: The capillary electrophoresis apparatus according to the present invention can maintain the temperature in the longitudinal direction of each of a plurality of capillaries uniformly, such that the separation performance of the capillary electrophoresis apparatus can be stabilized, and the analysis performance can be improved.Type: ApplicationFiled: March 8, 2018Publication date: February 20, 2020Inventors: Wataru SATO, Motohiro YAMAZAKI
-
Publication number: 20200047181Abstract: This sample processing device comprises: an analysis chip having a flow path on a lower surface side; a drive unit having a plurality of recesses on an upper surface side; an elastic film positioned between the analysis chip and the drive unit; and an air pressure control unit that switches whether the elastic film is adhered to the analysis chip side or adhered to the drive unit side. The analysis chip includes a quantitative flow path for quantifying liquid, and at least four branch flow paths branched from the quantitative flow path. The drive unit includes recesses below each of the ends of the four branch flow paths not on the quantitative flow path side, and each of the recesses communicates with the air pressure control unit.Type: ApplicationFiled: May 11, 2018Publication date: February 13, 2020Inventors: Yoshihiro NAGAOKA, Motohiro YAMAZAKI
-
Patent number: 10451553Abstract: During analysis of samples of unknown concentration, situations frequently occur in which the dynamic range is insufficient, necessitating reanalysis. Accordingly, a fluorescence spectrometer which splits a single object image into multiple images having different fluorescent intensity by means of image splitting elements, and simultaneously detects the plurality of images obtained thereby in different regions within the same detection plane, is proposed.Type: GrantFiled: March 18, 2015Date of Patent: October 22, 2019Assignee: Hitachi High-Technologies CorporationInventors: Motohiro Yamazaki, Yuichiro Ota, Satoshi Takahashi, Yoshitaka Kodama