Patents by Inventor Motoyuki Esaki

Motoyuki Esaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230372474
    Abstract: The present invention relates to recombinant herpes viruses comprising recombinant nucleotide sequences encoding at least two different antigens. The invention is particularly suited for producing vaccines to immunize avian species against avian pathogen(s).
    Type: Application
    Filed: October 14, 2021
    Publication date: November 23, 2023
    Inventors: Motoyuki Esaki, Vilmos Palya, Timea Tatar, Zoltan Penzes
  • Patent number: 10655146
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: May 19, 2020
    Assignee: BIOMUNE COMPANY
    Inventors: Motoyuki Esaki, Lauren Elizabeth Jensen, Kristi M. Dorsey
  • Patent number: 10246685
    Abstract: The present invention relates to recombinant MDV1 viruses and the uses thereof. The invention is particularly suited to vaccinate poultry against avian pathogens.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: April 2, 2019
    Assignee: CEVA SANTE ANIMALE
    Inventors: Yukari Ishihara, Motoyuki Esaki, Shuji Saitoh
  • Patent number: 10188720
    Abstract: The present invention relates recombinant viruses and the uses thereof. More particularly, the invention relates to novel recombinant Marek's disease viruses encoding polypeptide(s) of interest, and their use to express or deliver such polypeptides to animals, particularly poultry. The invention is particularly suited to vaccinate poultry against avian pathogens.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: January 29, 2019
    Assignee: CEVA SANTE ANIMALE
    Inventors: Motoyuki Esaki, Shuji Saitoh, Takanori Sato
  • Publication number: 20180363006
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Application
    Filed: August 28, 2018
    Publication date: December 20, 2018
    Inventors: MOTOYUKI ESAKI, LAUREN ELIZABETH JENSEN, KRISTI M. DORSEY
  • Patent number: 10072272
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: September 11, 2018
    Assignee: BIOMUNE COMPANY
    Inventors: Motoyuki Esaki, Lauren Elizabeth Jensen, Kristi M. Dorsey
  • Publication number: 20180016559
    Abstract: The present invention relates to recombinant MDV1 viruses and the uses thereof. The invention is particularly suited to vaccinate poultry against avian pathogens.
    Type: Application
    Filed: January 29, 2016
    Publication date: January 18, 2018
    Inventors: Yukari Ishihara, Motoyuki Esaki, Shuji Saitoh
  • Publication number: 20170298386
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Application
    Filed: November 24, 2014
    Publication date: October 19, 2017
    Inventors: Motoyuki ESAKI, Lauren Elizabeth Jensen, Kristi M. Dorsey
  • Publication number: 20160220657
    Abstract: The present invention relates recombinant viruses and the uses thereof. More particularly, the invention relates to novel recombinant Marek's disease viruses encoding polypeptide(s) of interest, and their use to express or deliver such polypeptides to animals, particularly poultry. The invention is particularly suited to vaccinate poultry against avian pathogens.
    Type: Application
    Filed: September 5, 2014
    Publication date: August 4, 2016
    Inventors: Motoyuki Esaki, Shuji Saitoh, Takanori Sato
  • Publication number: 20150110835
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Application
    Filed: November 24, 2014
    Publication date: April 23, 2015
    Inventors: Motoyuki ESAKI, Lauren Elizabeth Jensen, Kristi M. Dorsey
  • Patent number: 8927270
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: January 6, 2015
    Assignee: Zeon Corporation
    Inventors: Motoyuki Esaki, Lauren Elizabeth Jensen, Kristi M. Dorsey
  • Publication number: 20110311994
    Abstract: The present invention provides a poultry vaccine containing a positive marker gene. More specifically, recombinant turkey herpesvirus modified by the presence of an extraneous antigen gene that may be used as a positive marker to identify and track vaccinated animals is provided. When inoculated into host animals, a poultry vaccine comprising the recombinant turkey herpesvirus provided in the present invention can elicit serological immune responses to the marker gene product that may be detected by serological assays such as enzyme-linked immunosorbent assay and serum agglutination test, thus enabling easy identification and tracking of vaccinated animals.
    Type: Application
    Filed: March 16, 2009
    Publication date: December 22, 2011
    Inventors: Motoyuki Esaki, Takanori Sato, Kristi M. Dorsey
  • Publication number: 20090246226
    Abstract: The present invention provides a poultry vaccine containing a positive marker gene. More specifically, recombinant turkey herpesvirus modified by the presence of an extraneous antigen gene that may be used as a positive marker to identify and track vaccinated animals is provided. When inoculated into host animals, a poultry vaccine comprising the recombinant turkey herpesvirus provided in the present invention can elicit serological immune responses to the marker gene product that may be detected by serological assays such as enzyme-linked immunosorbent assay and serum agglutination test, thus enabling easy identification and tracking of vaccinated animals.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 1, 2009
    Applicant: ZEON CORPORATION
    Inventors: Motoyuki Esaki, Takanori Sato, Kristi M. Dorsey
  • Publication number: 20080241188
    Abstract: The present invention provides a recombinant turkey herpesvirus modified by the presence of the cDNA encoding the hemagglutinin protein of avian influenza virus under a promoter. A poultry vaccine comprising the recombinant turkey herpesvirus described in the present invention can induce serological responses that may be easily detected by the hemagglutination inhibition assay but not by commercially available diagnostic ELISA kits; thus enabling easy differentiation between vaccination and field infection.
    Type: Application
    Filed: March 30, 2007
    Publication date: October 2, 2008
    Applicant: ZEON CORPORATION
    Inventors: Motoyuki Esaki, Lauren Elizabeth Jensen, Kristi M. Dorsey
  • Patent number: 7153511
    Abstract: The present invention provides an avian recombinant herpesvirus modified by the presence of the cDNA encoding, the VP2 of the Delaware Variant E strain of IBDV, a subtype of IBDV serotype 1 strains. The present invention further provides an avian recombinant herpesvirus comprised of the VP2 gene of which the backbone virus is a Marek's disease vaccine strain, such as herpesvirus of turkeys. A poultry vaccine including the avian herpes recombinant virus described in the present invention can induce in chickens protective immunity against a variety of different subtypes of IBDV.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: December 26, 2006
    Assignee: Zeon Corporation
    Inventors: Takanori Sato, Yoshinari Tsuzaki, Motoyuki Esaki, Kristi M. Dorsey
  • Publication number: 20040197351
    Abstract: The present invention provides an avian recombinant herpesvirus modified by the presence of the cDNA encoding, the VP2 of the Delaware Variant E strain of IBDV, a subtype of IBDV serotype 1 strains. The present invention further provides an avian recombinant herpesvirus comprised of the VP2 gene of which the backbone virus is a Marek's disease vaccine strain, such as herpesvirus of turkeys. A poultry vaccine including the avian herpes recombinant virus described in the present invention can induce in chickens protective immunity against a variety of different subtypes of IBDV.
    Type: Application
    Filed: April 27, 2004
    Publication date: October 7, 2004
    Applicant: ZEON CORPORATION
    Inventors: Takanori Sato, Yoshinari Tsuzaki, Motoyuki Esaki, Kristi M. Dorsey
  • Patent number: 6375603
    Abstract: A bag for packing powder, permeable for gases and comprising a plurality of inwards protrudent hole-forming portions. Preferably, the bag comprises a film having holes (B) of predetermined thickness (d) furnished with protrudent hole-forming portions of predetermined height (h), the height (h) of the protrudent hole-forming portions being in the range of 2 to 200, still preferably 5 to 100, times the thickness (d) of the film having holes (B). By virtue of this structure, the soaring of powder at the time of powder filling can be prevented to thereby facilitate the filling operation. Furthermore, not only is the sticking of powder to seal portion reduced at the time of sealing the mouth of the bag to thereby ensure obtaining satisfactory seal strength but also the environmental pollution by the soaring of powder can be avoided.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: April 23, 2002
    Assignees: Mitsui Chemicals, Inc., Tokiwa Sangyo Co.
    Inventors: Haruo Yuasa, Isao Hata, Motoyuki Esaki, Hiroshi Suizu, Tatsuo Yamazaki