Patents by Inventor Muh-Lan Chen

Muh-Lan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8425931
    Abstract: The description provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C?O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: April 23, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Jui-Hsiang Chen, Bin-Hong Tsai, Hsuen-Tseng Chang, Muh-Lan Chen, Yu-Hua Chen, Shu-Hua Jan, Mei-Jung Liu
  • Patent number: 8313765
    Abstract: The invention provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C?O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: November 20, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Jui-Hsiang Chen, Bin-Hong Tsai, Hsuen-Tseng Chang, Muh-Lan Chen, Yu-Hua Chen, Shu-Hua Jan, Mei-Jung Liu
  • Publication number: 20120283429
    Abstract: The description provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C?O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
    Type: Application
    Filed: July 13, 2012
    Publication date: November 8, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jui-Hsiang Chen, Bin-Hong Tsai, Hsuen-Tseng Chang, Muh-Lan Chen, Yu-Hua Chen, Shu-Hua Jan, Mei-Jung Liu
  • Publication number: 20100316682
    Abstract: The invention provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C?O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group, and p is an integer of 1 to 4.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jui-Hsiang Chen, Bin-Hong Tsai, Hsuen-Tseng Chang, Muh-Lan Chen, Yu-Hua Chen, Shu-Hua Jan, Mei-Jung Liu
  • Patent number: 7780982
    Abstract: A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C?O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: August 24, 2010
    Assignee: Industrial Technology Research Instittute
    Inventors: Jui-Hsiang Chen, Bin-Hong Tsai, Hsuen-Tseng Chang, Muh-Lan Chen, Yu-Hua Chen, Shu-Hua Jan, Mei-Jung Liu
  • Patent number: 7655258
    Abstract: A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: February 2, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Bin-Hong Tsai, Jui-Hsiang Chen, Muh-Lan Chen, Yu-Hua Chen, Mei-Jung Liu
  • Publication number: 20050123505
    Abstract: A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C?O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.
    Type: Application
    Filed: November 18, 2004
    Publication date: June 9, 2005
    Inventors: Jui-Hsiang Chen, Bin-Hong Tsai, Hsuen-Tseng Chang, Muh-Lan Chen, Yu-Hua Chen, Shu-Hua Jan, Mei-Jung Liu
  • Publication number: 20050019303
    Abstract: A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.
    Type: Application
    Filed: December 29, 2003
    Publication date: January 27, 2005
    Inventors: Bin-Hong Tsai, Jui-Hsiang Chen, Muh-Lan Chen, Yu-Hua Chen, Mei-Jung Liu
  • Publication number: 20040099979
    Abstract: The present invention provides a process for preparing a porous material having interconnected pores. One or more kinds of bioresorbable polymers and a low molecular weight oligomer are dissolved in an organic solvent to form a bioresorbable polymer solution. The bioresorbable polymer solution is then exposed to a coagulant to form a porous material. The low molecular weight oligomer is soluble in the coagulant, and the bioresorbable polymer is insoluble in the coagulant.
    Type: Application
    Filed: November 14, 2003
    Publication date: May 27, 2004
    Inventors: Jui-Hsiang Chen, Jean-Dean Yang, Muh-Lan Chen, Kei-Hung Wu, Bin-Hong Tsai, Mei-Jun Liu, Yu-Lin Hsieh
  • Patent number: 5462704
    Abstract: A porous polyurethane tube suitable for use as a vascular graft prosthesis is prepared by placing solvent type polyurethane resin coated mandrel in a static coagulant consisting of water, ethanol and optionally aprotic solvent within 30 seconds immediately after the coating step, separating the tube by placing the mandrel in a swelling agent containing at least 90 percent by weight of ethanol and rinsing with a solution containing at least 80 percent by weight ethanol.
    Type: Grant
    Filed: April 26, 1994
    Date of Patent: October 31, 1995
    Assignee: Industrial Technology Research Institute
    Inventors: Jui-Hsiang Chen, Jeng Wei, Andrew T. Hu, Yu-Der Lee, Ru-Fong Laiw, Muh-Lan Chen, Chung-Yi Chang, Fan-Yen Lee, Shu-Fang Jiang
  • Patent number: 5308897
    Abstract: A composition of matter including a polymeric material which is either a plastic having carbon to carbon linkages or a binary blend of the plastic and starch, in which the plastic is at least 25% by weight of the binary blend; and an organic peracid compound dispersed in the polymeric material, the quantity of the peracid compound being 0.1 to 10% by weight of the polymeric material.
    Type: Grant
    Filed: January 14, 1993
    Date of Patent: May 3, 1994
    Assignee: Industrial Technology Research Institute
    Inventors: Hung-Yuan Hsu, Shu-Chieh Liuo, Shu-Fang Jiang, Jian-Hong Chen, Ho-May Lin, Herng-Dar Hwu, Muh-Lan Chen, Mao-Song Lee, Teh Hu