Patents by Inventor Munetaka Tokumasu

Munetaka Tokumasu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted benzenesulfonamides as inhibitors of alpha-4 beta-7 integrin activity
    Patent number: 10562898
    Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: February 18, 2020
    Assignee: EA PHARMA CO., LTD.
    Inventors: Munetaka Tokumasu, Masatsugu Noguchi, Mizuki Kawahira, Kana Iwasaki, Nobuhiko Hayakawa, Wataru Miyanaga, Yuki Saitou, Yui Yamaura, Ayatoshi Ando, Atsushi Tsuruta, Misato Noguchi
  • SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
    Publication number: 20190040059
    Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.
    Type: Application
    Filed: February 6, 2017
    Publication date: February 7, 2019
    Applicant: EA PHARMA CO., LTD.
    Inventors: Munetaka TOKUMASU, Masatsugu NOGUCHI, Mizuki KAWAHIRA, Kana IWASAKI, Nobuhiko HAYAKAWA, Wataru MIYANAGA, Yuki SAITOU, Yui YAMAURA, Ayatoshi ANDO, Atsushi TSURUTA, Misto NOGUCHI
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9655879
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: May 23, 2017
    Assignee: EA Pharma Co., Ltd.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • Heterocyclic carboxylic acid ester derivative
    Patent number: 9346821
    Abstract: The present invention provides a blood glucose elevation inhibitor having a serine protease inhibitory action, which is a novel therapeutic or prophylactic agent for obesity. A compound represented by the following formula (I) wherein each symbol is as described in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: May 24, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Tamotsu Suzuki, Takahiro Koshiba, Munetaka Tokumasu, Koji Ohsumi
  • PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES
    Publication number: 20160137633
    Abstract: Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. In the formula, Ar is an aromatic carbocyclic ring or a heterocyclic ring; and Ar2 is represented by any one of the following rings and the like.
    Type: Application
    Filed: January 29, 2016
    Publication date: May 19, 2016
    Applicant: Ajinomoto Co., Inc.
    Inventors: Tadakiyo NAKAGAWA, Kayo Matsumoto, Sen Takeshita, Tomomi Yoshida, Munetaka Tokumasu, Hiroki Inoue, Kaori Kobayashi
  • Pharmaceutical composition for treating diabetes
    Patent number: 9290487
    Abstract: Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. In the formula, Ar is an aromatic carbocyclic ring or a heterocyclic ring; and Ar2 is represented by any one of the following rings and the like.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: March 22, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Tadakiyo Nakagawa, Kayo Matsumoto, Sen Takeshita, Tomomi Yoshida, Munetaka Tokumasu, Hiroki Inoue, Kaori Kobayashi
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20160058734
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takahiro KOSHIBA, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9227949
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: January 5, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • NOVEL TETRAHYDROPYRIDOPYRIMIDINONE DERIVATIVE
    Publication number: 20150368242
    Abstract: An object is to provide a novel compound having a higher MGAT2 inhibitory activity than conventional compounds. A compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof is provided.
    Type: Application
    Filed: August 28, 2015
    Publication date: December 24, 2015
    Applicant: Ajinomoto Co., Inc.
    Inventors: Tamotsu Suzuki, Hiroki Inoue, Kayo Matsumoto, Takahiro Koshiba, Koji Ohsumi, Hiroki Ozawa, Munetaka Tokumasu, Masatsugu Noguchi
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150313889
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: July 14, 2015
    Publication date: November 5, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka TOKUMASU, Tamotsu SUZUKI, Takahiro KOSHIBA, Koji OHSUMI, Osamu IKEHARA, Yuko KODAMA
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9115107
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 25, 2015
    Assignee: AJINOMOTO CO., INC.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9024044
    Abstract: Compounds represented by the following formula (I), are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: May 5, 2015
    Assignee: Ajinomoto Co., Inc.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150099733
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: December 11, 2014
    Publication date: April 9, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takahiro KOSHIBA, Munetaka TOKUMASU, Taisuke ICHIMARU, Koji OHSUMI, Tadakiyo NAKAGAWA, Tatsuhiro YAMADA, Kayo MATSUMOTO, Tamotsu SUZUKI
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150011511
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: September 25, 2014
    Publication date: January 8, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka TOKUMASU, Tamotsu SUZUKI, Takahiro KOSHIBA, Koji OHSUMI, OSAMU IKEHARA, Yuko KODAMA
  • PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES
    Publication number: 20140336376
    Abstract: Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. In the formula, Ar is an aromatic carbocyclic ring or a heterocyclic ring; and Ar2 is represented by any one of the following rings and the like.
    Type: Application
    Filed: May 2, 2014
    Publication date: November 13, 2014
    Applicant: Ajinomoto Co., Inc.
    Inventors: Tadakiyo NAKAGAWA, Kayo Matsumoto, Sen Takeshita, Tomomi Yoshida, Munetaka Tokumasu, Hiroki Inoue, Kaori Kobayashi
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 8877805
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: November 4, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROCYCLIC CARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20140094489
    Abstract: The present invention provides a blood glucose elevation inhibitor having a serine protease inhibitory action, which is a novel therapeutic or prophylactic agent for obesity. A compound represented by the following formula (I) wherein each symbol is as described in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 6, 2013
    Publication date: April 3, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tamotsu SUZUKI, Takahiro KOSHIBA, Munetaka TOKUMASU, Koji OHSUMI
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20140080790
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20130338132
    Abstract: Compounds represented by the following formula (I), are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: June 14, 2012
    Publication date: December 19, 2013
    Applicant: Ajinomoto Co., Inc.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 8609715
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: December 17, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama