Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.

Abstract: A swimming pool skimmer comprises a buoyant skimmer body. The swimming pool skimmer further comprises an electrical power supply including a solar cell mounted to a topside of the skimmer body. A set of proximity sensors are operatively connected to the electrical power supply, and are mounted at a forward end of the skimmer body. The set of proximity sensors are configured to generate a signal in response to detecting an obstruction. A set of pump jets are operatively connected to both the electrical power supply and the set of proximity sensors. The set of pump jets are configured to activate in response to the signal from the set of proximity sensors, thereby rotating the swimming pool skimmer away from the obstruction.

Abstract: A modular pipe and a method of installing the pipe uses a first pipe section positioned in end to end relation with a second pipe section, the first and second pipe sections being precast from a cement-based material, wherein each pipe section has an outer surface, a flow passage, a first end, and a second end. Each end has a connection profile, an axis, and an end face that is perpendicular to the axis. A collar surrounds and secures the connection between adjacent ends. The collar is constructed from a plurality of collar elements. Each collar element overlaps the pipe connection and engages the connection profile along a portion of the perimeter of each of the first end of the second pipe section and the second end of the first pipe section.

Abstract: A tooth adapter defining top and bottom walls and side walls, an adapter recess in one side, a retention means in the adapter recess, a bolt with a fastening inserted in the recess, a collar formed on the bolt of predetermined diameter, a tooth having side walls and defining a hollow chamber fitting over the adaptor, a through tooth bolt opening formed in a tooth side wall of predetermined diameter, the tooth bolt opening being located to register with the adaptor recess, when the tooth is positioned on the adapter. In one version the diameter of the collar is slightly greater than the diameter of the tooth bolt opening, to create a locking effect.

Abstract: There is provided a compound of formula I: or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

Abstract: An application configured to be a text-to-speech (“TTS”) application wherein the application is capable of reading a document aloud to a reviewer via a device, such as a smartphone, an mp3 device, or a tablet, while the reviewer is able to make amendments to the document in real-time is presented.

Abstract: The present invention relates to the recognition that inhibition of the base excision repair pathway is selectively lethal in cells which are deficient in HR dependent DNA DSB repair. Methods and means relating to the treatment of cancers which are deficient in HR dependent DNA DSB repair using inhibitors which target base excision repair components, such as PARP, is provided herein.

Abstract: With a view to providing such an apparatus, the invention comprises a tooth adapter defining top and bottom walls and side walls, an adapter recess in one side, a retention means in the adapter recess, a bolt with a fastening inserted in the recess, a collar formed on the bolt of predetermined diameter, a tooth having side walls and defining a hollow chamber fitting over said adapter, a through tooth bolt opening formed in a tooth side wall of predetermined diameter, said tooth bolt opening being located to register with said adapter recess, when the tooth is positioned on the adapter. In one version the diameter of the collar is slightly greater than the diameter of the tooth bolt opening, to create a locking effect.

Abstract: There is provided a compound of formula I: or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

Abstract: There is provided a compound of formula I: or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

Abstract: A method of producing a pasta filata cheese product, such as a Mozzarella-type cheese, in a continuous process without emulsifier or pH regulator additives requires preparing a typical pasta filata-type cheese curd and supplying the curd in cut pieces to one end of a processing chamber. The chamber has an agitator which rotates to work, knead, stretch and move the curd through the chamber. At the same time, steam is injected into the curd in the chamber through a plurality of injection nozzles spaced along the length of the chamber to heat and cook the cheese while it is mechanically worked. The cooked product exiting from the chamber is molded to a desired shape.

Abstract: A water turbine includes a base and an axle extending upwardly relative to the base. A body is provided having an axle receiving bore positioned along a longitudinal rotational axis. The axle is positioned in the axle receiving bore, such that the body rotates about the longitudinal rotational axis. A weight bearing roller assembly is positioned between a lower end of the body and the base to facilitate the body rotating relative to the base. Vanes extend radially from the body, such that flowing water striking the vanes imparts a rotational force to the body.

Abstract: A method for reducing loudspeaker magnitude and/or phase distortion, in which one or more filters pertaining to one or more drive units is automatically generated or modified based on the response of each specific drive unit. The drive unit response may be determined by electromechanical modelling of the drive unit. Drive unit models may be enhanced by electromechanical and/or acoustic measurement such that the resulting filter becomes specific to each specific drive unit.

Abstract: A ripper tip includes a front end, a rear end, and a mounting cavity extending into the rear end. The ripper tip further includes an upper surface extending between the front end and the rear end, wherein a portion of the upper surface at the rear end of the ripper tip includes an upwardly projecting ridge having ridge sides and a ridge top that extend rearwardly on the ripper tip.

Abstract: There is provided a compound of formula I: or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

Abstract: A method of building a structure in the presence of water includes providing two or more three-sided elongated triangular bodies that has a first end, a second end, and an internal flow passage that extends between the first end and the second end. Each of the triangular bodies has an apex with a base opposed to the apex. Each of the triangular bodies is positioned in side by side relation, with the flow passage of one or more of the triangular bodies serving as a flow path for water. A road, a bridge or a dock is positioned transversely across the triangular bodies.

Abstract: There is provided a compound of formula I: or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

Abstract: A system and method for rapidly responding to and regaining control of uncontrolled flow from offshore hydrocarbon wells, that includes a subsea containment assembly, optionally including a capture caisson assembly installed around the assembly, riser systems for production of hydrocarbons to capture vessels on the surface of the sea, and modularized subsystems facilitating communication between and fluid flow from the subsea containment assembly through the riser to the capture vessel.

Abstract: A ripper tip includes a front end, a rear end, and a mounting cavity extending into the rear end. The ripper tip further includes an upper surface extending between the front end and the rear end, wherein a portion of the upper surface at the rear end of the ripper tip includes an upwardly projecting ridge having ridge sides and a ridge top that extend rearwardly on the ripper tip.