Patents by Inventor Muthukrishnan Murugan

Muthukrishnan Murugan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 3-aryl-2-hydroxy propanoic acid compounds
    Patent number: 9550719
    Abstract: The present disclosure provides a process for synthesis of 3-aryl-2-hydroxy propanoic acid derivatives of formula (S)-1. wherein R1 represents H or (C1-C5) alkyl groups and R2 represents (C1-C5) alkyl groups.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: January 24, 2017
    Assignee: Council of Scientific and Industrial Research
    Inventors: Muthukrishnan Murugan, Mujahid Mohammad
  • Process for the preparation of an anticonvulsant agent pregabalin hydrochloride
    Patent number: 9422230
    Abstract: An efficient synthesis of the anticonvulsant drug, Pregabalin hydrochloride is described using simple transformations in high enantiopurity (>99% ee) and overall yield of 44 to 50%.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: August 23, 2016
    Assignee: Council of Scientific and Industrial Research
    Inventors: Muthukrishnan Murugan, Mujahid Mohammad
  • PROCESS FOR THE PREPARATION OF AN ANTICONVULSANT AGENT PREGABALIN HYDROCHLORIDE
    Publication number: 20160122289
    Abstract: An efficient synthesis of the anticonvulsant drug, Pregabalin hydrochloride is described using simple transformations in high enantiopurity (>99% ee) and overall yield of 44 to 50%.
    Type: Application
    Filed: May 9, 2014
    Publication date: May 5, 2016
    Inventors: Muthukrishnan MURUGAN, Mujahid MOHAMMAD
  • A PROCESS FOR THE PREPARATION OF 3-ARYL-2-HYDROXY PROPANOIC ACID COMPOUNDS
    Publication number: 20160102042
    Abstract: The present disclosure provides a process for synthesis of 3-aryl-2-hydroxy propanoic acid derivatives of formula (S)-1. wherein R1 represents H or (C1-C5) alkyl groups and R2 represents (C1-C5) alkyl groups.
    Type: Application
    Filed: May 9, 2014
    Publication date: April 14, 2016
    Inventors: Muthukrishnan Murugan, Mujahid Mohammad
  • Process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline
    Patent number: 9199930
    Abstract: Disclosed herein a novel, process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline [(S)-1]. Particularly, the invention relates to the synthesis of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline with excellent selectivity starting from commercially available enantiopure (R)-epichlorohydrin [(R)-2] via formation of aziridine intermediate [(S)-4].
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: December 1, 2015
    Assignee: Council of Scientific and Industrial Research
    Inventors: Muthukrishnan Murugan, Prashant Pramod Mujumdar
  • PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE
    Publication number: 20150225340
    Abstract: Disclosed herein a novel, process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline [(S)-1]. Particularly, the invention relates to the synthesis of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline with excellent selectivity starting from commercially available enantiopure (R)-epichlorohydrin [(R)-2] via formation of aziridine intermediate [(S)-4].
    Type: Application
    Filed: September 6, 2013
    Publication date: August 13, 2015
    Inventors: Muthukrishnan Murugan, Prashant Pramod Mujumdar
  • Process for the synthesis of antiepileptic drug lacosamide
    Patent number: 8748660
    Abstract: The present invention relates to the improved and efficient process for the synthesis of antiepileptic drug Lacosamide in high enantiopurity (>98% ee) and better yield. More particularly, the present invention relates to improved and efficient, cost effective process for synthesis of desired (R) isomer of Lacosamide starting from commercially available (S)-benzyl glycidyl ether.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: June 10, 2014
    Assignee: Council of Scientific & Industrial Research
    Inventors: Muthukrishnan Murugan, Mohammad Mujahid, Prashant Pramod Majumdar
  • PROCESS FOR THE SYNTHESIS OF ANTIEPILEPTIC DRUG LACOSAMIDE
    Publication number: 20140012044
    Abstract: The present invention relates to the improved and efficient process for the synthesis of antiepileptic drug Lacosamide in high enantiopurity (>98% ee) and better yield. More particularly, the present invention relates to improved and efficient, cost effective process for synthesis of desired (R) isomer of Lacosamide starting from commercially available (S)-benzyl glycidyl ether.
    Type: Application
    Filed: August 20, 2012
    Publication date: January 9, 2014
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Muthukrishnan MURUGAN, Mohammad MUJAHID, Prashant Pramod MUJUMDAR
  • RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol
    Patent number: 7227039
    Abstract: The present invention relates to RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol of the formula (1), process for preparation thereof by selective allylation of p-hydroxy phenyl ethanol and use thereof in a preparation of RS betaxolol of formula (2)
    Type: Grant
    Filed: November 1, 2004
    Date of Patent: June 5, 2007
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ramesh Anna Joshi, Muthukrishnan Murugan, Dinesh Ramesh Garud, Sanjay Pandurang Borikar, Mukund Keshav Gurjar
  • RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol
    Publication number: 20060094903
    Abstract: The present invention relates to RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol of the formula (1), process for preparation thereof by selective allylation of p-hydroxy phenyl ethanol and use thereof in a preparation of RS betaxolol of formula (2)
    Type: Application
    Filed: November 1, 2004
    Publication date: May 4, 2006
    Inventors: Ramesh Joshi, Muthukrishnan Murugan, Dinesh Garud, Sanjay Borikar, Mukund Gurjar
  • Process for preparation of S-(-)-betaxolol and salts thereof
    Patent number: 7019172
    Abstract: The present invention relates to an improved process for preparation of S-(?)-betaxolol salts.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: March 28, 2006
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ramesh Anna Joshi, Muthukrishnan Murugan, Dinesh Ramesh Garud, Sanjay Pandurang Borikar, Mukund Keshav Gurjar
  • S-(?)-1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of S-(?)betaxolo
    Patent number: 6989465
    Abstract: The present invention relates to a novel compound S-(?)-1-{4-[2-(allyloxy)-ethyl] phenoxy}-3-isopropylamino propan-2-ol of formula 1 and to a process for the preparation thereof. More particularly the present invention relates to a process for preparing S-(?)-1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol of formula 1 by selective allylation of p-hydroxy phenyl ethanol.
    Type: Grant
    Filed: November 1, 2004
    Date of Patent: January 24, 2006
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ramesh Anna Joshi, Muthukrishnan Murugan, Dinesh Rämesh Garud, Sanjay Pandurang Borikar, Mukund Keshav Gurjar
  • PROCESS FOR PREPARATION OF S-(-)-BETAXOLOL AND SALTS THEREOF
    Publication number: 20060004109
    Abstract: The present invention relates to an improved process for preparation of S-(?)-betaxolol salts. More particularly the present invention relates to the preparation of hydrochloride salt of S-(?)-betaxolol of formula (1).
    Type: Application
    Filed: June 30, 2004
    Publication date: January 5, 2006
    Applicant: Council of Scientific and Industrial Research
    Inventors: Ramesh Joshi, Muthukrishnan Murugan, Dinesh Garud, Sanjay Borikar, Mukund Gurjar