Patents by Inventor Myles Lindsay

Myles Lindsay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR OBTAINING A COMPOSITION COMPRISING HUMAN PLASMA-DERIVED IMMUNOGLOBULIN M
    Publication number: 20240010710
    Abstract: A method for preparing a composition of human plasma-derived immunoglobulin M (IgM) includes PEG precipitation of the IgM, resuspension of the precipitated IgM; (c) performing an adsorption chromatography, removing isoagglutinins A/B, nanofiltration, and ultrafiltration/diafiltration. The precipitation can be performed at a pH between 4.5 and 6.5, and the PEG can be at a concentration between 5 (w/v) and 11% (w/v).
    Type: Application
    Filed: July 8, 2021
    Publication date: January 11, 2024
    Inventors: Myles LINDSAY, Thomas P. ZIMMERMAN, Michelle WOZNICHAK, Deepa SINGH, Erin ROMES, Natalia ORLOVA, Rebecca SILVERSTEIN
  • HYPERIMMUNE IGG AND/OR IGM COMPOSITIONS AND METHOD FOR PREPARING THEREOF AND METHOD FOR OBTAINING HYPERIMMUNE HUMAN PLASMA FROM A DONOR
    Publication number: 20230218744
    Abstract: Hyperimmune IgG and/or IgM compositions and method for preparing thereof and method for obtaining hyperimmune human plasma from a donor. A liquid therapeutic hyperimmune globulin composition including human plasma-derived immunoglobulin G (IgG) having antibody titre between 250 and 2,500 per mg/mL of IgG and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titer) between 1.5 and 15 per mg/mL of IgG for use in the treatment of coronavirus disease 2019 (COVID-19) in a patient in need thereof. A liquid therapeutic or prophylactic hyperimmune immunoglobulin composition including human plasma-derived immunoglobulin M (IgM) having a SARS-CoV-2 titre between 2,000 and 17,000 and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titre) between 200 and 70,000, methods for preparing thereof, and the use thereof for the treatment or prophylaxis of COVID-19. A method for obtaining hyperimmune human plasma from a donor for use in the treatment of COVID-19.
    Type: Application
    Filed: May 26, 2021
    Publication date: July 13, 2023
    Inventors: Peter VANDEBERG, Andrea WELLHOUSE, Marta JOSE, Marilyn ROSA-BRAY, Charles AUGER, Rodrigo GAJARDO RODRÍGUEZ, Myles LINDSAY, Natalia ORLOVA, Erin ROMES
  • Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom
    Patent number: 9206410
    Abstract: Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: December 8, 2015
    Assignee: GRIFOLS THERAPEUTICS INC.
    Inventors: Edward Koepf, Myles Lindsay, Rebecca Silverstein, Jennifer Hunt, James Rebbeor, Thomas Zimmerman, Charles Miller, Anthony Caronna, Kenya Stokes
  • COMPOSITIONS, METHODS, AND KITS FOR PREPARING PLASMINOGEN; AND PLASMIN PREPARED THEREFROM
    Publication number: 20150329845
    Abstract: Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 19, 2015
    Inventors: Edward Koepf, Myles Lindsay, Rebecca Silverstein, Jennifer Hunt, James Rebbeor, Thomas Zimmerman, Charles Miller, Anthony Caronna, Kenya Stokes