Abstract: The present invention relates to a composition for preventing, improving, or treating diseases related to advanced glycation end products, comprising an indole derivative or a pharmaceutically acceptable salt thereof. Specifically, the composition of the present invention possesses the effect of trapping methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.

Abstract: The present invention relates to a novel indole derivative and a use thereof. The novel indole derivative according to the present invention traps methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.

Abstract: The present invention related to a functional agent for decomposing nicotine and a method of preparing the same. The agent includes natural plant extracts such as green tea leaves, mulberry leaves, ginkgo nuts, celery, lemon, apple, dried orange peel, and licorice root. The functional agent of the present invention facilitates the decomposition of nicotine and inhibits the generation of carcinogen. In addition, the functional agent shows an anti-oxidant effect, inhibits mutation and remarkably reduces the generation rate of lung cancer.

Abstract: The present invention related to a functional agent for decomposing nicotine and a method of preparing the same. The agent includes natural plant extracts such as green tea leaves, mulberry leaves, ginkgo nuts, celery, lemon, apple, dried orange peel, and licorice root. The functional agent of the present invention facilitates the decomposition of nicotine and inhibits the generation of carcinogen. In addition, the functional agent shows an anti-oxidant effect, inhibits mutation and remarkably reduces the generation rate of lung cancer.

Abstract: Koji is produced from soybean hypocotyl as a koji substrate by: (a) soaking the soybean hypocotyl in water for a period ranging from 1 min to 30 hrs; (b) steaming the soaked soybean hypocotyl at a temperature ranging from 90 to 140° C.; (c) inoculating Bacillus sp., Aspergilllus sp or a mixture thereof to the steamed soybean hypocotyl in an amount ranging from 0.01 to 10 wt % based on the total weight of the soybean hypocotyl; and (d) culturing the inoculated soybean hypocotyl at a temperature ranging from 15 to 55° C., a relative humidity ranging from 40 to 100% and at a pH ranging from 3 to 10 for a period ranging from 1 to 8 days.