Abstract: Proposed is a refrigerator. The refrigerator may include: main doors open and closed, while sealing a storage room of the refrigerator, and having accommodation spaces and a dispenser located therein; sub-doors open and closed, while sealing the accommodation spaces, and connected to the main doors; and an ice making room connected to one side main door to supply water or ice to the dispenser, while being connected to refrigerant pipe of the refrigerator.

Abstract: Proposed is a refrigerator. The refrigerator may include: one or more main doors open and closed, while sealing a storage room of the refrigerator, and having convenience space and a dispenser provided therein; sub-doors open and closed, while sealing the convenience space, and connected to the main doors; and an ice making room connected to one side main door to supply water or ice to the dispenser.

Abstract: Proposed is an ice maker disposed in a refrigerator to provide ice to an ice bucket. The ice maker may include a tray configured to be filled with water and positioned in the ice maker to freeze the water to make ice, the tray includes a high thermal conductive composite material configured to emit heat in response to an electric current supplied thereto; a tray cap connected to top of the tray to reduce an area of top of the tray so that the water filled in the tray is prevented from overflowing because of the inertia generated by the movement of the tray; a frame assembly connected to the tray; electrodes connected to both sides of the tray, respectively; and a motor connected to the tray to rotate the tray so that the ice is separated from the tray by gravity.

Abstract: The blood-brain barrier penetrant procaspase-3-activating drug, PAC-1, has been identified as an effective approach to inducing immune stimulatory destruction of cancer cells. PAC-1 induces cleavage of MLH1 in cancer cells, and studies show that inactivation of MLH1 leads to increased mutational burden and neoantigen presentation by major histocompatibility complex (MHC) products. Herein is described a mechanistic-based strategy to bring the power of immunotherapy in an effective fashion for treatment of cancer.

Abstract: The present invention relates to a production method of ?-methylene lactone which comprises the following steps: (A) a step of producing an enolate intermediate by making lactone react with alkyl formate under the presence of an alkoxide base; and (B) making the enolate intermediate react with paraformaldehyde. The production method of the present invention is capable of reducing the process time, improving yield, and minimizing the contamination of a reactor.

Abstract: A refrigeration-cycle apparatus is provided that includes a plurality of evaporators having various temperature bands, along with a refrigerator including a plurality of cooling compartments to enable stable and even cooling operations in various temperature bands using the plurality of evaporators. The refrigeration-cycle apparatus and the refrigerator enable individual operation of a portion of the plurality of evaporators, thereby reducing consumption of energy and enabling accurate control of an interior temperature of the refrigerator. The refrigeration-cycle apparatus includes a compressor that compresses and discharges a refrigerant, a condensing device including at least one condenser that condenses the refrigerant discharged from the compressor, a distributor that distributes the refrigerant condensed in the condensing device, and a cold air generator including a plurality of evaporators that evaporates the refrigerant distributed by the distributor.

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

Abstract: Disclosed is a dispenser of an icemaker in a refrigerator for maximizing an inner space when a total size is the same, and for minimizing the total size when the inner space is the same. The dispenser of the icemaker in the refrigerator includes an ice chute being a passage through which the ice produced from the icemaker is discharged; and a container supporter provided at an outer case and disposed to be perpendicular to an outer surface of the outer case when the ice is discharged outside through the ice chute, the contain supporter allowing a container seated thereon to receive the ice discharged from the ice chute. The ice chute is closed and not exposed outside when the ice-discharging process is finished, and the container supporter is not exposed to the outer surface of the outer case.

Abstract: The present invention relates to a pharmaceutical composition comprising compound for induction of apoptosis, a method for inducing cancer cell apoptosis, a method to suppress lymphocyte activation, a method to improve intracellular trafficking of misfolded mutants and a screening method to identify additional compounds useful for inducing apoptosis, and more specifically, it relates to pharmaceutical compositions comprising imidazole derivatives as active gradients for induction of apoptosis to treat various diseases including cancers and immune-related diseases, the method of inducing apoptosis by treating cancer cells with the pharmaceutical composition, the method of inactivating human lymphocytes by treating lymphocytes with the pharmaceutical composition, the method of improving intracellular trafficking of misfolded mutants by treating cells containing the mutants with the pharmaceutical composition, and the screening method for identifying additional compound useful for inducing apoptosis, wherein cel

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

Abstract: The present invention provides a refrigerator, in which cold-storage (1) and freezer rooms (2) are situated at upper and lower parts, respectively, in which ice made at the freezer room (2) of the lower part is dispensed at the cold-storage room (1) of the upper part, and by which a user can pick up the ice without bending over to enhance user's convenience. The present invention includes a body (B) having a cold-storage room (1) provided to an upper part and a freezer room (2) provided to a lower part, an ice maker (400) provided to the freezer room to make ice, an ice bank (600) receiving the ice made by the ice maker, and a transport mechanism sending the ice discharged from the ice bank (600) toward the cold-storage room (1) via an ice transport passage (200a, 300). Therefore, the present invention sufficiently secures the spaces of the cold-storage and freezer rooms to raise spatial efficiency.

Abstract: The present invention relates to 4,5-bis(4-methoxyphenyl)imidazole compound inducing differentiation of myoblasts or muscle fibers into neuron cells, a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation. More specifically, it relates to 2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole that induces differentiation of myoblasts or muscle fibers into neuron cells, all pharmaceutically acceptable isomers, salts, and a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation.

Abstract: A refrigerator includes a main body having cooling chambers for keeping food items therein, a base frame disposed to be movable in outward and inward directions in a lower cooling chamber disposed at a lower portion of the main body, and having a basket door at its front side, a lift frame disposed on the base frame, on which the basket is put, a fluid pressure cylinder mounted at the base frame and connected to the lift frame to lift the lift frame, and an fluid compressor connected to the fluid pressure cylinder by an fluid supply pipe and supplying compressed fluid to the fluid pressure cylinder. Accordingly, as the basket is lifted when being drawn out, a user can take out food items kept in the basket without bending his/her back, which enhances user's convenience.

Abstract: A refrigerator is disclosed in which cool air ducts guide cool air from a freezing chamber to an ice making chamber provided at a refrigerating chamber door. The cool air ducts are provided at a barrier sectioning the freezing chamber and the refrigerating chamber and at the refrigerating chamber door.

Abstract: A refrigerator includes a body; a compartment within the body; a container within the compartment, the container being moveable along a first direction; an electrical device, the electrical device moving along with the container in the first direction when the container moves along the first direction; and a conductor for providing an electrical signal to the electrical device, the conductor being extendable and retractable in the first direction when the electrical device moves along the first direction.

Abstract: Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.