Patents by Inventor N. Adeyinka Williams

N. Adeyinka Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lyophilized imaging agent formulation comprising a chemotactic peptide
    Patent number: 6024938
    Abstract: A lyophilized imaging agent formulation and methods for making same are disclosed, such formulations comprise a targeting molecule such as antibody or chemotactic peptide, a linker such as diethylenetriaminepentaacetic acid (DTPA) or succinimidyl 6-hydrazinium nicotinate hydrochloride (SHNH), drying protectant such as mannitol, maltose or tricine, and excipient such as polysorbate 80, in citrate buffer. The formulations of the invention are lyophilized and may be stored stably for extended periods of time. Following reconstitution with diluent, the formulations are administered to a subject for scintigraphic imaging or therapeutic use. Also contemplated is a kit comprising a two-vial system wherein a first vial comprises a lyophilized formulation of imaging agent in the form of a lyophilized cake, and a second vial comprises a pharmaceutically acceptable carrier or diluent.
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: February 15, 2000
    Assignees: Ortho Pharmaceutical Corporation, Johnson-Matthey Inc.
    Inventors: Diane C. Corbo, Mary Jean M. Link, N. Adeyinka Williams, Michelle L. Tomsho, Michael Bornstein, Howard F. Solomon, Scott K. Larsen, Robert L. Suddith
  • Lyophilized pulmonary surfactant peptide compositions
    Patent number: 5952303
    Abstract: An improved solid pharmaceutical composition comprising a lyophilized liposomal KL4 pulmonary surfactant composition comprising:(a) about 1 to about 10 percent weight KL4 polypeptide; and(b) 50 to about 100 weight percent phospholipid comprised of about 3 parts DPPC to about 1 part POPG.A facile process for the production of the lyophilized solid composition is also provided.
    Type: Grant
    Filed: March 29, 1997
    Date of Patent: September 14, 1999
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Michael Bornstein, N. Adeyinka Williams
  • Injectable formulation for lipophilic drugs
    Patent number: 5085864
    Abstract: An injectable drug composition including a therapeutically effective amount of a lipophilic drug and a bile salt.
    Type: Grant
    Filed: May 20, 1991
    Date of Patent: February 4, 1992
    Assignee: Abbott Laboratories
    Inventors: John B. Cannon, Chung-Chiang Hsu, Karen J. Papp, N. Adeyinka Williams